| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.139075 |
| RPS6 | ribosomal protein S6 | 0.0896348 |
| MT2A | metallothionein 2A | 0.0740842 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0598233 |
| HSPA8 | heat shock 70kDa protein 8 | 0.056059 |
| CENPF | centromere protein F, 350/400kDa | 0.0547372 |
| RAD51B | RAD51 paralog B | 0.0512275 |
| PTMA | prothymosin, alpha | 0.0512271 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0501091 |
| TPI1 | triosephosphate isomerase 1 | 0.0496702 |
| EGR1 | early growth response 1 | 0.0478602 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0451761 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0437421 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0429626 |
| RPS12 | ribosomal protein S12 | 0.0420604 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0388336 |
| RPS8 | ribosomal protein S8 | 0.0385017 |
| MKI67 | marker of proliferation Ki-67 | 0.038303 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0373445 |
| RPS2 | ribosomal protein S2 | 0.0362042 |
| FTL | ferritin, light polypeptide | 0.0361518 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0360839 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0351377 |
| RPS19 | ribosomal protein S19 | 0.0334607 |
| RPS23 | ribosomal protein S23 | 0.0334341 |
| PLK2 | polo-like kinase 2 | 0.0333588 |
| BRD4 | bromodomain containing 4 | 0.0331927 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0328767 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0323267 |
| HLA-A | major histocompatibility complex, class I, A | 0.0312968 |
| RPS3 | ribosomal protein S3 | 0.0307611 |
| RPL18 | ribosomal protein L18 | 0.0298448 |
| RPL36 | ribosomal protein L36 | 0.0293858 |
| RPS17 | ribosomal protein S17 | 0.0278811 |
| SRPK2 | SRSF protein kinase 2 | 0.0278438 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.02768 |
| RCOR1 | REST corepressor 1 | 0.02694 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0268725 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264531 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0263508 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0260234 |
| RACK1 | receptor for activated C kinase 1 | 0.0256289 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0255901 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0252292 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.024786 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0246555 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0238323 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0236254 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0236146 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0234327 |
| HDGF | hepatoma-derived growth factor | 0.0232153 |
| RPL7A | ribosomal protein L7a | 0.0228027 |
| NHSL1 | NHS-like 1 | 0.0224831 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0221498 |
| CCNL1 | cyclin L1 | 0.0220651 |
| RNF213 | ring finger protein 213 | 0.0218913 |
| TMF1 | TATA element modulatory factor 1 | 0.0217274 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0216662 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0212136 |
| DIAPH3 | diaphanous-related formin 3 | 0.021135 |
| UPP1 | uridine phosphorylase 1 | 0.0209567 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.020861 |
| RPLP2 | ribosomal protein, large, P2 | 0.0208247 |
| RPS29 | ribosomal protein S29 | 0.0207346 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0204152 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0203368 |
| RPL27 | ribosomal protein L27 | 0.0201309 |
| PFN1 | profilin 1 | 0.0201169 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0196405 |
| WDR27 | WD repeat domain 27 | 0.0193224 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0191758 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0190009 |
| CCDC88A | coiled-coil domain containing 88A | 0.0188636 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0188465 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.018681 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0185866 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0184013 |
| RPL8 | ribosomal protein L8 | 0.0183665 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0182053 |
| RPL21 | ribosomal protein L21 | 0.0180633 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0180057 |
| STRBP | spermatid perinuclear RNA binding protein | 0.017954 |
| BRCA1 | breast cancer 1, early onset | 0.0179246 |
| B2M | beta-2-microglobulin | 0.0178176 |
| RPS27 | ribosomal protein S27 | 0.0178128 |
| DENND2B | DENN domain containing 2B | 0.0177767 |
| SSH2 | slingshot protein phosphatase 2 | 0.0177314 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0176274 |
| NXN | nucleoredoxin | 0.0176158 |
| EXOC4 | exocyst complex component 4 | 0.01752 |
| ATXN2 | ataxin 2 | 0.0175118 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0174382 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0172629 |
| CENPP | centromere protein P | 0.016925 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0168793 |
| RPL10A | ribosomal protein L10a | 0.0168405 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.01684 |
| PNN | pinin, desmosome associated protein | 0.016813 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0168024 |
| RPS14 | ribosomal protein S14 | 0.0168013 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.198907 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.189921 |
| VIM | vimentin | -0.18119 |
| TMSB4X | thymosin beta 4, X-linked | -0.169397 |
| DST | dystonin | -0.145986 |
| CD44 | CD44 molecule (Indian blood group) | -0.121865 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.11749 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.112414 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.10702 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0983536 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0951741 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0935078 |
| AHNAK | AHNAK nucleoprotein | -0.0854406 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0853864 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0777794 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.075159 |
| TP63 | tumor protein p63 | -0.0748022 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0739546 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0734827 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0712478 |
| SPAG9 | sperm associated antigen 9 | -0.0694642 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0691943 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0671404 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.061777 |
| EMP1 | epithelial membrane protein 1 | -0.0608328 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0585283 |
| APP | amyloid beta (A4) precursor protein | -0.0568777 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0554569 |
| EZR | ezrin | -0.055194 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0539045 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0527292 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0523452 |
| ANXA1 | annexin A1 | -0.051491 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0507581 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0505944 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0481171 |
| PYGB | phosphorylase, glycogen; brain | -0.0466359 |
| PGK1 | phosphoglycerate kinase 1 | -0.0465399 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0456459 |
| CANX | calnexin | -0.0448092 |
| KLF6 | Kruppel-like factor 6 | -0.0435249 |
| ANXA2 | annexin A2 | -0.0425925 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0423863 |
| TXNRD1 | thioredoxin reductase 1 | -0.0418425 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0418098 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0417304 |
| RTN4 | reticulon 4 | -0.0415818 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0411781 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0411042 |
| POTEF | POTE ankyrin domain family, member F | -0.040271 |
| CAPRIN2 | caprin family member 2 | -0.0400649 |
| LDHA | lactate dehydrogenase A | -0.0395135 |
| RPL35A | ribosomal protein L35a | -0.0392379 |
| EREG | epiregulin | -0.0390878 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0385536 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0375624 |
| RPS24 | ribosomal protein S24 | -0.0375604 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0370484 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0363367 |
| USP34 | ubiquitin specific peptidase 34 | -0.0359799 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0353748 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0348948 |
| OGA | O-GlcNAcase | -0.0341482 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0337781 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0337161 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0333577 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0333321 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0332901 |
| ACTG1 | actin gamma 1 | -0.0332595 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0325624 |
| RUNX1 | runt-related transcription factor 1 | -0.0321443 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.031993 |
| MATR3 | matrin 3 | -0.0316539 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0314115 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0313177 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0312596 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0308623 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0307265 |
| SBF2 | SET binding factor 2 | -0.0302827 |
| RGS4 | regulator of G-protein signaling 4 | -0.0296804 |
| MYOF | myoferlin | -0.0287048 |
| EHBP1 | EH domain binding protein 1 | -0.0286389 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0286329 |
| TNPO1 | transportin 1 | -0.0285448 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0280108 |
| PYGL | phosphorylase, glycogen, liver | -0.027804 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0277175 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0277054 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0273926 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.027344 |
| JMJD1C | jumonji domain containing 1C | -0.0271652 |
| TPM4 | tropomyosin 4 | -0.0270533 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0270103 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0269018 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0266119 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0263499 |
| TOP1 | topoisomerase (DNA) I | -0.0260573 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0256949 |
| ETNK1 | ethanolamine kinase 1 | -0.0256325 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0254731 |
