| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.107683 |
| RUNX1 | runt-related transcription factor 1 | 0.0793988 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0757017 |
| MT2A | metallothionein 2A | 0.0728025 |
| MKI67 | marker of proliferation Ki-67 | 0.072375 |
| CES1 | carboxylesterase 1 | 0.0595119 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0472577 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0469405 |
| RPL4 | ribosomal protein L4 | 0.0421488 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0408859 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0407912 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0392568 |
| RPS3 | ribosomal protein S3 | 0.0373828 |
| NGLY1 | N-glycanase 1 | 0.0367271 |
| LAMB3 | laminin, beta 3 | 0.0365925 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0365618 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0352661 |
| RNF145 | ring finger protein 145 | 0.0351397 |
| SLTM | SAFB-like, transcription modulator | 0.0329411 |
| NDE1 | nudE neurodevelopment protein 1 | 0.032226 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0321433 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0321118 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0301329 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0293749 |
| KIAA1328 | KIAA1328 | 0.0286161 |
| RPS2 | ribosomal protein S2 | 0.0285254 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0278655 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0265884 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0265756 |
| NPTN | neuroplastin | 0.0261342 |
| RPS6 | ribosomal protein S6 | 0.0259894 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0255094 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0254291 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0251701 |
| GPATCH2L | G patch domain containing 2-like | 0.0250913 |
| CENPF | centromere protein F, 350/400kDa | 0.024833 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0246415 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.024555 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0240335 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0238442 |
| ECT2 | epithelial cell transforming 2 | 0.0235247 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233851 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0232892 |
| SGO2 | shugoshin 2 | 0.022905 |
| DTNA | dystrobrevin, alpha | 0.0227699 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0226052 |
| OGA | O-GlcNAcase | 0.022316 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.021958 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0216527 |
| ZNF292 | zinc finger protein 292 | 0.0216258 |
| PRELID2 | PRELI domain containing 2 | 0.021567 |
| ATP13A3 | ATPase type 13A3 | 0.0215018 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.021378 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0211435 |
| KIAA1217 | KIAA1217 | 0.0211113 |
| HELZ | helicase with zinc finger | 0.0207157 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0204664 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203309 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0202206 |
| PER1 | period circadian clock 1 | 0.0201974 |
| MYO1B | myosin IB | 0.020059 |
| CYTH1 | cytohesin 1 | 0.0199186 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0197784 |
| RBM39 | RNA binding motif protein 39 | 0.0197718 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0196227 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0194765 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0194504 |
| UVRAG | UV radiation resistance associated | 0.0192614 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0192325 |
| ANO6 | anoctamin 6 | 0.0191836 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0190817 |
| RASA2 | RAS p21 protein activator 2 | 0.0188445 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0188377 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0187211 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0185213 |
| NEK7 | NIMA-related kinase 7 | 0.018321 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.018271 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0181156 |
| CDC73 | cell division cycle 73 | 0.0179616 |
| TFG | TRK-fused gene | 0.017727 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.017643 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0175644 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0175556 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.017522 |
| METTL15 | methyltransferase like 15 | 0.0175195 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0174339 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0173636 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.016915 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0168608 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0168206 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0168132 |
| CCNL1 | cyclin L1 | 0.016444 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0163349 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0162117 |
| KIF14 | kinesin family member 14 | 0.0162081 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0162014 |
| FRY | furry homolog (Drosophila) | 0.0161305 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0159932 |
| PAPOLA | poly(A) polymerase alpha | 0.0159336 |
| RPS8 | ribosomal protein S8 | 0.0158413 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.270721 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.252096 |
| TMSB10 | thymosin beta 10 | -0.136797 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.12593 |
| ASPH | aspartate beta-hydroxylase | -0.104046 |
| NDRG1 | N-myc downstream regulated 1 | -0.0967893 |
| LDHA | lactate dehydrogenase A | -0.0966493 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0955194 |
| PKM | pyruvate kinase, muscle | -0.0949286 |
| ACTG1 | actin gamma 1 | -0.090147 |
| LMO7 | LIM domain 7 | -0.0846206 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0838099 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0833272 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0744612 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0710785 |
| MYOF | myoferlin | -0.0705036 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0691679 |
| ANXA2 | annexin A2 | -0.0688086 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0673292 |
| S100A10 | S100 calcium binding protein A10 | -0.0657877 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0613828 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.060713 |
| KRT7 | keratin 7, type II | -0.0594322 |
| EGR1 | early growth response 1 | -0.0592411 |
| CST3 | cystatin C | -0.0589447 |
| GRAMD1B | GRAM domain containing 1B | -0.0587179 |
| INTS6 | integrator complex subunit 6 | -0.0559323 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0546116 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0540706 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0536916 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0527781 |
| POTEF | POTE ankyrin domain family, member F | -0.0497566 |
| RNF213 | ring finger protein 213 | -0.0490326 |
| SCEL | sciellin | -0.0488203 |
| PTMA | prothymosin, alpha | -0.0469381 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0462188 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0456409 |
| CAV2 | caveolin 2 | -0.0453675 |
| KRT18 | keratin 18, type I | -0.0437832 |
| CANX | calnexin | -0.0435954 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0433031 |
| TPM4 | tropomyosin 4 | -0.0430903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0421898 |
| CCND1 | cyclin D1 | -0.0421544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0414193 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0386268 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0381817 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0378701 |
| CUX1 | cut-like homeobox 1 | -0.0373129 |
| AHNAK | AHNAK nucleoprotein | -0.0365269 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0351097 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.034671 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0338529 |
| KRT8 | keratin 8, type II | -0.0332445 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0332109 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0323094 |
| S100A6 | S100 calcium binding protein A6 | -0.031763 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0310611 |
| CMIP | c-Maf inducing protein | -0.0310283 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0309292 |
| FOXP1 | forkhead box P1 | -0.0304113 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0302412 |
| ENO1 | enolase 1, (alpha) | -0.0299335 |
| DSPP | dentin sialophosphoprotein | -0.0298216 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0298054 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.029619 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0291351 |
| HMGA1 | high mobility group AT-hook 1 | -0.0287036 |
| AGR2 | anterior gradient 2 | -0.028463 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0283189 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0281138 |
| PRKCA | protein kinase C, alpha | -0.0276334 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0274122 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0272815 |
| PARD3 | par-3 family cell polarity regulator | -0.0272284 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0272173 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0270838 |
| EFNA5 | ephrin-A5 | -0.0270272 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0266167 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0265729 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0264396 |
| FLNB | filamin B, beta | -0.0262488 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259768 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0258226 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0256791 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0256505 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0255973 |
| PDE8A | phosphodiesterase 8A | -0.0250519 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0249759 |
| KRT19 | keratin 19, type I | -0.0248142 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0247571 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0247023 |
| BPTF | bromodomain PHD finger transcription factor | -0.0246859 |
| RAB10 | RAB10, member RAS oncogene family | -0.0246125 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.024051 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0239876 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0239394 |
| GNAS | GNAS complex locus | -0.0238562 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0237216 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0236954 |
