| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.144202 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0972307 |
| SMAD3 | SMAD family member 3 | 0.091207 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0789328 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0765575 |
| PCBP2 | poly(rC) binding protein 2 | 0.0716621 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0662269 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0630467 |
| RBM39 | RNA binding motif protein 39 | 0.0582069 |
| GOLGA4 | golgin A4 | 0.0542673 |
| FAM13A | family with sequence similarity 13, member A | 0.0493181 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.048963 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0469985 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0468751 |
| ZNF292 | zinc finger protein 292 | 0.0411781 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0401892 |
| OGA | O-GlcNAcase | 0.0400727 |
| RUNX1 | runt-related transcription factor 1 | 0.0392681 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0392083 |
| RNF145 | ring finger protein 145 | 0.0373439 |
| NAV2 | neuron navigator 2 | 0.0368363 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0354036 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0353855 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0339874 |
| COG5 | component of oligomeric golgi complex 5 | 0.0330022 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0323053 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0321258 |
| USP3 | ubiquitin specific peptidase 3 | 0.0318165 |
| ATP13A3 | ATPase type 13A3 | 0.0313108 |
| SBF2 | SET binding factor 2 | 0.0311989 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.031174 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0310073 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0303816 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0302344 |
| PRELID2 | PRELI domain containing 2 | 0.0300539 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0295274 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0291038 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0290318 |
| NBAS | neuroblastoma amplified sequence | 0.0286128 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0285227 |
| AHR | aryl hydrocarbon receptor | 0.0284453 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0282897 |
| HELZ | helicase with zinc finger | 0.0280807 |
| CENPF | centromere protein F, 350/400kDa | 0.0276185 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0274629 |
| SIK3 | SIK family kinase 3 | 0.0274199 |
| RPL4 | ribosomal protein L4 | 0.0268659 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0264037 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0258047 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0256319 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0255893 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0251668 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0250687 |
| CCNL1 | cyclin L1 | 0.0246909 |
| SRP54 | signal recognition particle 54kDa | 0.024388 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0243046 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0242568 |
| ANXA1 | annexin A1 | 0.0241303 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0239835 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0238727 |
| TPR | translocated promoter region, nuclear basket protein | 0.0238506 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0233332 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0233299 |
| SLTM | SAFB-like, transcription modulator | 0.0232549 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0230207 |
| CENPE | centromere protein E, 312kDa | 0.0226874 |
| VMP1 | vacuole membrane protein 1 | 0.022576 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0221405 |
| PHIP | pleckstrin homology domain interacting protein | 0.0218952 |
| YBX3 | Y box binding protein 3 | 0.0218629 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0215153 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0213111 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0211832 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0211504 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0210801 |
| CABIN1 | calcineurin binding protein 1 | 0.0210702 |
| DUSP5 | dual specificity phosphatase 5 | 0.0207149 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0207143 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0206444 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0204437 |
| LRRC49 | leucine rich repeat containing 49 | 0.0204195 |
| TPX2 | TPX2, microtubule-associated | 0.0203558 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0203172 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201054 |
| RTTN | rotatin | 0.0199791 |
| XPO1 | exportin 1 | 0.0198255 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0196621 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0196451 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0195049 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0194426 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0193238 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0192 |
| CDC73 | cell division cycle 73 | 0.0190679 |
| RPS2 | ribosomal protein S2 | 0.0189185 |
| FAM107B | family with sequence similarity 107, member B | 0.0188455 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0188397 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0188197 |
| SUCO | SUN domain containing ossification factor | 0.0187855 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0187642 |
| KIF5B | kinesin family member 5B | 0.0186686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.15651 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.146768 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.115116 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.112557 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.106071 |
| NRG1 | neuregulin 1 | -0.103995 |
| CDH13 | cadherin 13 | -0.10387 |
| GLCCI1 | glucocorticoid induced 1 | -0.0960023 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0917655 |
| FAM20C | family with sequence similarity 20, member C | -0.0884098 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0880864 |
| VIM | vimentin | -0.0880658 |
| MTSS1 | metastasis suppressor 1 | -0.0804148 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0794616 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.077969 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.077678 |
| MEF2A | myocyte enhancer factor 2A | -0.0753916 |
| STC1 | stanniocalcin 1 | -0.0735961 |
| HMGA2 | high mobility group AT-hook 2 | -0.071228 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0707489 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0692704 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.068566 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0677926 |
| TMSB10 | thymosin beta 10 | -0.0658902 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0648249 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0643912 |
| LOX | lysyl oxidase | -0.0642206 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0631695 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0626608 |
| RAI14 | retinoic acid induced 14 | -0.059639 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0594587 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0581314 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.057853 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0544864 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0522016 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0497614 |
| CLMP | CXADR-like membrane protein | -0.0494412 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0488655 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479774 |
| FBN1 | fibrillin 1 | -0.0472805 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0466704 |
| EXT1 | exostosin glycosyltransferase 1 | -0.044014 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0440122 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0439327 |
| IL1B | interleukin 1, beta | -0.0437842 |
| OSMR | oncostatin M receptor | -0.0431543 |
| CDK14 | cyclin-dependent kinase 14 | -0.0420951 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.041889 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0415574 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.041488 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0409517 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0404168 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0393681 |
| S100A6 | S100 calcium binding protein A6 | -0.037656 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0362224 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0360376 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0354255 |
| ENOSF1 | enolase superfamily member 1 | -0.034671 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0344186 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0342237 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0341951 |
| WLS | wntless Wnt ligand secretion mediator | -0.0333898 |
| PYGL | phosphorylase, glycogen, liver | -0.0331715 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0330313 |
| AHNAK | AHNAK nucleoprotein | -0.0329326 |
| NTN4 | netrin 4 | -0.0327691 |
| HLA-B | major histocompatibility complex, class I, B | -0.0326372 |
| DIAPH2 | diaphanous-related formin 2 | -0.0319214 |
| OXR1 | oxidation resistance 1 | -0.0317281 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0316827 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0316692 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.031604 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0298299 |
| CLIC4 | chloride intracellular channel 4 | -0.0296719 |
| SNX9 | sorting nexin 9 | -0.0293933 |
| CP | ceruloplasmin (ferroxidase) | -0.0293194 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0293045 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0291843 |
| THBD | thrombomodulin | -0.0290308 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0288798 |
| CUX1 | cut-like homeobox 1 | -0.0288384 |
| NUMB | numb homolog (Drosophila) | -0.0287538 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0285976 |
| TMSB4X | thymosin beta 4, X-linked | -0.028559 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0285491 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0284937 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0284876 |
| SEPTIN9 | septin 9 | -0.0280731 |
| RASAL2 | RAS protein activator like 2 | -0.0277059 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0276464 |
| ANXA10 | annexin A10 | -0.0274224 |
| PRRX1 | paired related homeobox 1 | -0.0270988 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0270739 |
| DNER | delta/notch-like EGF repeat containing | -0.0270593 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0270497 |
| AADAC | arylacetamide deacetylase | -0.0268009 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0264625 |
| HPCAL1 | hippocalcin-like 1 | -0.0263999 |
| BMERB1 | bMERB domain containing 1 | -0.0260451 |
| RNF213 | ring finger protein 213 | -0.0259954 |
