| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0936925 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0594589 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0584792 |
| EGFR | epidermal growth factor receptor | 0.058375 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0540941 |
| GLIS3 | GLIS family zinc finger 3 | 0.0531781 |
| PRRC2B | proline-rich coiled-coil 2B | 0.053137 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0515284 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0514169 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0500924 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0498093 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0485494 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0485138 |
| RPLP1 | ribosomal protein, large, P1 | 0.0477832 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0474718 |
| TPM3 | tropomyosin 3 | 0.0472454 |
| FNBP1 | formin binding protein 1 | 0.047243 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0468283 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0464909 |
| LMBR1 | limb development membrane protein 1 | 0.0459765 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0458514 |
| FNIP1 | folliculin interacting protein 1 | 0.0457218 |
| TCF12 | transcription factor 12 | 0.0455416 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0453648 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0448982 |
| SCFD1 | sec1 family domain containing 1 | 0.0448602 |
| RPS20 | ribosomal protein S20 | 0.0448599 |
| CCNL1 | cyclin L1 | 0.0448573 |
| YBX1 | Y box binding protein 1 | 0.0443665 |
| TOP1 | topoisomerase (DNA) I | 0.0442171 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0438111 |
| TRIM56 | tripartite motif containing 56 | 0.0436272 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0434318 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0433393 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0426151 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0424091 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0423805 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0422022 |
| GPHN | gephyrin | 0.0421494 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0420877 |
| RPS6 | ribosomal protein S6 | 0.0419057 |
| RPS8 | ribosomal protein S8 | 0.0417213 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0414667 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.041428 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0407827 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0407518 |
| CD44 | CD44 molecule (Indian blood group) | 0.0407509 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0406867 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0403077 |
| STK38 | serine/threonine kinase 38 | 0.0402402 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.039876 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0398254 |
| FRMD5 | FERM domain containing 5 | 0.0397865 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0396742 |
| GPC6 | glypican 6 | 0.0396175 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0395272 |
| WTAP | Wilms tumor 1 associated protein | 0.0391741 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.0390932 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0390265 |
| ENSA | endosulfine alpha | 0.0389987 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0389216 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.038897 |
| ETF1 | eukaryotic translation termination factor 1 | 0.0385484 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0383659 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0382888 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0382772 |
| ZNF207 | zinc finger protein 207 | 0.0382595 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0379662 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0374222 |
| PPHLN1 | periphilin 1 | 0.0373628 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0372485 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0370396 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0365708 |
| SETX | senataxin | 0.0363898 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0362209 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0356958 |
| PRKCA | protein kinase C, alpha | 0.0356849 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0354742 |
| RPL12 | ribosomal protein L12 | 0.0352696 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0352291 |
| RPS5 | ribosomal protein S5 | 0.0352139 |
| PODXL | podocalyxin-like | 0.0350354 |
| HYOU1 | hypoxia up-regulated 1 | 0.0347824 |
| VCP | valosin containing protein | 0.0346258 |
| FAM120B | family with sequence similarity 120B | 0.0345333 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0345217 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0344797 |
| EGR1 | early growth response 1 | 0.0342731 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0340837 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0338492 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0336598 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0336466 |
| FLNA | filamin A, alpha | 0.0335739 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0335288 |
| SYAP1 | synapse associated protein 1 | 0.0334672 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0334319 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0333382 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0333273 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0330532 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0329695 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.193815 |
| GRB10 | growth factor receptor-bound protein 10 | -0.162559 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.160557 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.137612 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.130005 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.124448 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.123231 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.121585 |
| LMO7 | LIM domain 7 | -0.116901 |
| ANXA2 | annexin A2 | -0.114237 |
| DSCAM | Down syndrome cell adhesion molecule | -0.103742 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.101466 |
| LAMB3 | laminin, beta 3 | -0.0972283 |
| PARD3 | par-3 family cell polarity regulator | -0.0960511 |
| FN1 | fibronectin 1 | -0.0929839 |
| MYO1E | myosin IE | -0.0870565 |
| NDRG1 | N-myc downstream regulated 1 | -0.0840067 |
| NEBL | nebulette | -0.0820074 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.081261 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0805288 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0775527 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0754267 |
| AHNAK | AHNAK nucleoprotein | -0.0752405 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.068795 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0670856 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0648669 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0643351 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0642399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0638217 |
| GOLGB1 | golgin B1 | -0.0636668 |
| KRT17 | keratin 17, type I | -0.061997 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0608955 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0567289 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0550612 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0549659 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0544692 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0542933 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0540961 |
| ATOSA | atos homolog A | -0.0540875 |
| ABHD17C | abhydrolase domain containing 17C | -0.0532585 |
| KIAA1217 | KIAA1217 | -0.0532554 |
| DSG2 | desmoglein 2 | -0.0528017 |
| RIGI | RNA sensor RIG-I | -0.0521333 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0520187 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0514694 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0503089 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0499685 |
| SMYD3 | SET and MYND domain containing 3 | -0.0497562 |
| USP53 | ubiquitin specific peptidase 53 | -0.0492712 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0488808 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0478622 |
| SVIL | supervillin | -0.0466029 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0460218 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0449404 |
| WDR45B | WD repeat domain 45B | -0.0445637 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0439523 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0432953 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.042826 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0425391 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0423614 |
| RUFY1 | RUN and FYVE domain containing 1 | -0.0422237 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0419903 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0417238 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0416786 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0414823 |
| AUTS2 | autism susceptibility candidate 2 | -0.0405767 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0404343 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0402863 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0399561 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0398511 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0396566 |
| MYOF | myoferlin | -0.0394797 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0392387 |
| RORA | RAR-related orphan receptor A | -0.0387654 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0386414 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0380263 |
| SETD5 | SET domain containing 5 | -0.0378089 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0378018 |
| CEP350 | centrosomal protein 350kDa | -0.0376419 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0372869 |
| STAG2 | stromal antigen 2 | -0.0369545 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0368567 |
| TANK | TRAF family member-associated NFKB activator | -0.0366874 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0362565 |
| TXNIP | thioredoxin interacting protein | -0.0362225 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0358764 |
| LDHA | lactate dehydrogenase A | -0.0357754 |
| MTSS1 | metastasis suppressor 1 | -0.03548 |
| ENO1 | enolase 1, (alpha) | -0.0352745 |
| ZNF638 | zinc finger protein 638 | -0.0346576 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0344297 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0341403 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0341112 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.033251 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0330354 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0328172 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0327705 |
| CDCP1 | CUB domain containing protein 1 | -0.0325715 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0324646 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0319796 |
