| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | 0.044841 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0361025 |
| PCBP2 | poly(rC) binding protein 2 | 0.0322452 |
| TPM3 | tropomyosin 3 | 0.0320879 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0297183 |
| HDGF | hepatoma-derived growth factor | 0.0278377 |
| TOP1 | topoisomerase (DNA) I | 0.0276801 |
| RPS12 | ribosomal protein S12 | 0.0252519 |
| RPL4 | ribosomal protein L4 | 0.0247089 |
| RPS6 | ribosomal protein S6 | 0.0240628 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0229899 |
| FLNA | filamin A, alpha | 0.0229178 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0212234 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0210908 |
| RPL21 | ribosomal protein L21 | 0.0209645 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0208144 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.020758 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0203238 |
| TLN1 | talin 1 | 0.0189482 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0183974 |
| SET | SET nuclear proto-oncogene | 0.0183103 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.018243 |
| PNN | pinin, desmosome associated protein | 0.0181818 |
| RPL26 | ribosomal protein L26 | 0.017691 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0171949 |
| RPL37A | ribosomal protein L37a | 0.0171118 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0166139 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.0165878 |
| TUBA1B | tubulin, alpha 1b | 0.0161962 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0161764 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0160683 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0160482 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0156921 |
| RPL18 | ribosomal protein L18 | 0.0155142 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0154355 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0153598 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0152932 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0152278 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0152106 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0151845 |
| PPHLN1 | periphilin 1 | 0.0151731 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0149288 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0148501 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0148351 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0147313 |
| TPI1 | triosephosphate isomerase 1 | 0.0146055 |
| STK38L | serine/threonine kinase 38 like | 0.0145065 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0141346 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.014102 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0138899 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0138028 |
| DSTN | destrin (actin depolymerizing factor) | 0.0134664 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0128508 |
| RPS3 | ribosomal protein S3 | 0.0123744 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0122842 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0122754 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0121243 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0121022 |
| CDC14A | cell division cycle 14A | 0.0119597 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0119299 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0118261 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0117556 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0117228 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.0116589 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0115959 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0115525 |
| UBXN7 | UBX domain protein 7 | 0.0115176 |
| RPL3 | ribosomal protein L3 | 0.0114022 |
| TJAP1 | tight junction associated protein 1 (peripheral) | 0.0113868 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0113363 |
| HCFC1 | host cell factor C1 | 0.0112462 |
| RAB13 | RAB13, member RAS oncogene family | 0.0111596 |
| PTMS | parathymosin | 0.0111496 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0111193 |
| RPS7 | ribosomal protein S7 | 0.0108835 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0108359 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0108166 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0108112 |
| TSC22D4 | TSC22 domain family, member 4 | 0.0107661 |
| RPS17 | ribosomal protein S17 | 0.0107136 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 0.0106071 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0105539 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0105404 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0105095 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0104838 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G | 0.0104815 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.0104738 |
| CENPF | centromere protein F, 350/400kDa | 0.0104689 |
| CRTC2 | CREB regulated transcription coactivator 2 | 0.0102753 |
| HMG20B | high mobility group 20B | 0.010275 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0101129 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.0100606 |
| SSRP1 | structure specific recognition protein 1 | 0.0100295 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00993479 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.00991935 |
| GRN | granulin | 0.00989608 |
| MRPL51 | mitochondrial ribosomal protein L51 | 0.00987482 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00986236 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00986068 |
| RSRP1 | arginine/serine-rich protein 1 | 0.00980028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.112861 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0906226 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0874753 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.07148 |
| NF1 | neurofibromin 1 | -0.064255 |
| GRAMD1B | GRAM domain containing 1B | -0.0604724 |
| FBXO11 | F-box protein 11 | -0.0575298 |
| RPL35A | ribosomal protein L35a | -0.0573005 |
| PTMA | prothymosin, alpha | -0.0567422 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0556148 |
| USP34 | ubiquitin specific peptidase 34 | -0.0534981 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0527203 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0494993 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0492845 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0492498 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0488412 |
| RSF1 | remodeling and spacing factor 1 | -0.0476196 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0474572 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0474049 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0468034 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0446229 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0438596 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.043358 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0428367 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0424187 |
| MCL1 | myeloid cell leukemia 1 | -0.0406706 |
| TMSB10 | thymosin beta 10 | -0.0395617 |
| RAD51B | RAD51 paralog B | -0.0392311 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0386612 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0385367 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0384502 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0384293 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0382886 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0380417 |
| SBF2 | SET binding factor 2 | -0.0375446 |
| ACTG1 | actin gamma 1 | -0.0375357 |
| COPA | coatomer protein complex, subunit alpha | -0.0374407 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0364643 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0360256 |
| PGK1 | phosphoglycerate kinase 1 | -0.0360177 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0359921 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0356164 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0355611 |
| RBM39 | RNA binding motif protein 39 | -0.0355285 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0352955 |
| RPL23 | ribosomal protein L23 | -0.0352354 |
| VIM | vimentin | -0.0351574 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0349054 |
| NABP1 | nucleic acid binding protein 1 | -0.0347963 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0345855 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0341356 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.033499 |
| UBC | ubiquitin C | -0.0333688 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0331726 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0331203 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0329206 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0325168 |
| CANX | calnexin | -0.0324704 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0321291 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.031973 |
| RPLP1 | ribosomal protein, large, P1 | -0.0317718 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0314109 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0313882 |
| ENO1 | enolase 1, (alpha) | -0.0312423 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0312233 |
| JMJD1C | jumonji domain containing 1C | -0.0306878 |
| KPNB1 | karyopherin (importin) beta 1 | -0.030498 |
| AHNAK | AHNAK nucleoprotein | -0.0304649 |
| TMEM131 | transmembrane protein 131 | -0.0304576 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0304438 |
| RPLP0 | ribosomal protein, large, P0 | -0.0304105 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0300996 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0299154 |
| ZNF217 | zinc finger protein 217 | -0.0298001 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.029625 |
| ZFR | zinc finger RNA binding protein | -0.0296065 |
| PYGL | phosphorylase, glycogen, liver | -0.0294921 |
| RAB10 | RAB10, member RAS oncogene family | -0.0294849 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0293057 |
| ZNF292 | zinc finger protein 292 | -0.0292077 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0291946 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0290303 |
| CCND2 | cyclin D2 | -0.0289754 |
| VCL | vinculin | -0.0289672 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0287568 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282775 |
| VMP1 | vacuole membrane protein 1 | -0.0281329 |
| BBX | bobby sox homolog (Drosophila) | -0.0280291 |
| RASAL2 | RAS protein activator like 2 | -0.0280012 |
| RHEB | Ras homolog enriched in brain | -0.0279461 |
| ADAR | adenosine deaminase, RNA-specific | -0.0278621 |
| DENND5B | DENN/MADD domain containing 5B | -0.0277869 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0276186 |
| ZNF207 | zinc finger protein 207 | -0.0275552 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0275314 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0271427 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0270343 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0270182 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0269856 |
