| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.145447 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117124 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.112518 |
| RPS3 | ribosomal protein S3 | 0.0619007 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0591663 |
| RPS6 | ribosomal protein S6 | 0.0540544 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0522283 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.049406 |
| FAM13A | family with sequence similarity 13, member A | 0.0486388 |
| HMGB2 | high mobility group box 2 | 0.0477811 |
| RPS2 | ribosomal protein S2 | 0.0471189 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0457165 |
| HSPA8 | heat shock 70kDa protein 8 | 0.044081 |
| MT2A | metallothionein 2A | 0.0432545 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0400227 |
| ZNF292 | zinc finger protein 292 | 0.0373821 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.034415 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0339426 |
| RPL4 | ribosomal protein L4 | 0.0337497 |
| ASPH | aspartate beta-hydroxylase | 0.0335413 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0331583 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0329199 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0327678 |
| RACK1 | receptor for activated C kinase 1 | 0.0318857 |
| ANLN | anillin, actin binding protein | 0.03077 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0305609 |
| USP3 | ubiquitin specific peptidase 3 | 0.0299242 |
| RNF145 | ring finger protein 145 | 0.0297184 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.029658 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0288467 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0284587 |
| NUP58 | nucleoporin 58 | 0.0276765 |
| PAPOLA | poly(A) polymerase alpha | 0.0272229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.026657 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.026101 |
| RPS8 | ribosomal protein S8 | 0.0260022 |
| QKI | QKI, KH domain containing, RNA binding | 0.0257103 |
| LAMB3 | laminin, beta 3 | 0.0253826 |
| AREG | amphiregulin | 0.0249045 |
| RPL13A | ribosomal protein L13a | 0.0246509 |
| TFG | TRK-fused gene | 0.0246239 |
| RPS12 | ribosomal protein S12 | 0.0243029 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0237832 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0234535 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233643 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0231853 |
| TPX2 | TPX2, microtubule-associated | 0.0228427 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.022715 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0223604 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.02229 |
| FTL | ferritin, light polypeptide | 0.0222629 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0222259 |
| RLF | rearranged L-myc fusion | 0.0217547 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0216264 |
| RPL21 | ribosomal protein L21 | 0.0216064 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0214551 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0213333 |
| H1-4 | H1.4 linker histone, cluster member | 0.0211463 |
| GPX4 | glutathione peroxidase 4 | 0.0210943 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0209324 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0208476 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0203116 |
| WBP11 | WW domain binding protein 11 | 0.0200643 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0198939 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0195711 |
| YBX3 | Y box binding protein 3 | 0.0194939 |
| RYBP | RING1 and YY1 binding protein | 0.0191647 |
| EZR | ezrin | 0.018875 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0188446 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0186528 |
| EGR1 | early growth response 1 | 0.0185655 |
| FOSL1 | FOS-like antigen 1 | 0.0182265 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0181069 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0179053 |
| MKI67 | marker of proliferation Ki-67 | 0.0178852 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0177819 |
| FAM162A | family with sequence similarity 162, member A | 0.0174417 |
| RPL28 | ribosomal protein L28 | 0.0173644 |
| YBX1 | Y box binding protein 1 | 0.0171821 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0171776 |
| CENPE | centromere protein E, 312kDa | 0.0171244 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0166822 |
| RYK | receptor-like tyrosine kinase | 0.0163905 |
| PTTG1 | pituitary tumor-transforming 1 | 0.016288 |
| NDRG1 | N-myc downstream regulated 1 | 0.0161623 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0161448 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0161435 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0161389 |
| FBXO33 | F-box protein 33 | 0.0160519 |
| TUBA1B | tubulin, alpha 1b | 0.0160411 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0157831 |
| PNN | pinin, desmosome associated protein | 0.0157684 |
| BRD2 | bromodomain containing 2 | 0.0155745 |
| RPS27 | ribosomal protein S27 | 0.0155192 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0155165 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0155144 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0153315 |
| SUCO | SUN domain containing ossification factor | 0.0153052 |
| RPL37A | ribosomal protein L37a | 0.0151317 |
| MXD1 | MAX dimerization protein 1 | 0.0149861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.23183 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.147956 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.134756 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.134001 |
| TMSB10 | thymosin beta 10 | -0.129785 |
| FN1 | fibronectin 1 | -0.112076 |
| EXT1 | exostosin glycosyltransferase 1 | -0.111087 |
| ERBIN | erbb2 interacting protein | -0.101809 |
| FBXO32 | F-box protein 32 | -0.097251 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.093272 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.085433 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0824011 |
| ACTG1 | actin gamma 1 | -0.0801584 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0750007 |
| KRT7 | keratin 7, type II | -0.0734024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0732015 |
| S100A6 | S100 calcium binding protein A6 | -0.0731952 |
| TPM4 | tropomyosin 4 | -0.0706312 |
| RPL35A | ribosomal protein L35a | -0.0687561 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0682814 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0664397 |
| UBC | ubiquitin C | -0.0663476 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0663143 |
| CCND1 | cyclin D1 | -0.0616861 |
| GRB10 | growth factor receptor-bound protein 10 | -0.06127 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0609969 |
| MYO6 | myosin VI | -0.058865 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0584076 |
| MAP1B | microtubule-associated protein 1B | -0.0577328 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0562735 |
| CD2AP | CD2-associated protein | -0.0561758 |
| EFNA5 | ephrin-A5 | -0.0558541 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0552691 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0552447 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.05311 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0529284 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0528016 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.051982 |
| RNF213 | ring finger protein 213 | -0.0518895 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0512441 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0507112 |
| TMSB4X | thymosin beta 4, X-linked | -0.0503633 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0502367 |
| MX2 | MX dynamin-like GTPase 2 | -0.0497047 |
| LMO7 | LIM domain 7 | -0.0491224 |
| TMEM165 | transmembrane protein 165 | -0.0483283 |
| GOLGB1 | golgin B1 | -0.044768 |
| MYO1E | myosin IE | -0.0439653 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0438826 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0435113 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0434819 |
| RAB7A | RAB7A, member RAS oncogene family | -0.043185 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0429938 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.041367 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.041144 |
| OCLN | occludin | -0.0411317 |
| VCL | vinculin | -0.0409991 |
| ETV6 | ets variant 6 | -0.0406277 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0399207 |
| HLA-B | major histocompatibility complex, class I, B | -0.0398005 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0395552 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0394231 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0393837 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0392028 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0386963 |
| PTMA | prothymosin, alpha | -0.0384554 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0378856 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0377398 |
| KRT8 | keratin 8, type II | -0.0376033 |
| NF1 | neurofibromin 1 | -0.0374384 |
| RPL23 | ribosomal protein L23 | -0.037334 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0372348 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0371837 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0369555 |
| PLSCR1 | phospholipid scramblase 1 | -0.0367914 |
| PTK2 | protein tyrosine kinase 2 | -0.0365678 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0363705 |
| SVIL | supervillin | -0.0361614 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0360472 |
| AHNAK | AHNAK nucleoprotein | -0.035899 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0358887 |
| MX1 | MX dynamin-like GTPase 1 | -0.0356143 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0354508 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0352599 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0351612 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0350089 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0350056 |
| MCU | mitochondrial calcium uniporter | -0.0348154 |
| FBXO34 | F-box protein 34 | -0.0346812 |
| VEGFA | vascular endothelial growth factor A | -0.0345665 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0338911 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0336728 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0334398 |
| ARF4 | ADP-ribosylation factor 4 | -0.032593 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0323558 |
| RAI14 | retinoic acid induced 14 | -0.0322746 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0322331 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0321477 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0321184 |
| CTSB | cathepsin B | -0.0318247 |
