| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Epirubicin (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | 0.0846518 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.077879 |
| VCL | vinculin | 0.0584021 |
| MT2A | metallothionein 2A | 0.0476072 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0466639 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0459966 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0441334 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0437681 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0420863 |
| RPS2 | ribosomal protein S2 | 0.0415939 |
| SMYD3 | SET and MYND domain containing 3 | 0.0401904 |
| RPL4 | ribosomal protein L4 | 0.0394731 |
| MKI67 | marker of proliferation Ki-67 | 0.0394252 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.038223 |
| ANLN | anillin, actin binding protein | 0.0375755 |
| RPS3 | ribosomal protein S3 | 0.0370823 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0357821 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0350449 |
| ASPH | aspartate beta-hydroxylase | 0.0332193 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0329787 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0323112 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0317698 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.029324 |
| TXNRD1 | thioredoxin reductase 1 | 0.0291373 |
| VMP1 | vacuole membrane protein 1 | 0.0287268 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0281591 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0278603 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0277521 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0274079 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0268917 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0267892 |
| FHL2 | four and a half LIM domains 2 | 0.0263828 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0256513 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.025499 |
| MED29 | mediator complex subunit 29 | 0.0254482 |
| SMAD3 | SMAD family member 3 | 0.0249126 |
| RPS6 | ribosomal protein S6 | 0.0244043 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0241802 |
| FANCI | Fanconi anemia, complementation group I | 0.0236908 |
| RPL12 | ribosomal protein L12 | 0.0236201 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0236136 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0234417 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0230886 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0228209 |
| YBX3 | Y box binding protein 3 | 0.0226044 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0225268 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) | 0.0220676 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0220131 |
| EFNA5 | ephrin-A5 | 0.0219654 |
| TUBA1B | tubulin, alpha 1b | 0.0218967 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0218263 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0210668 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0210282 |
| RACK1 | receptor for activated C kinase 1 | 0.0208601 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0203938 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0203237 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.0201447 |
| KLF6 | Kruppel-like factor 6 | 0.0200794 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0200095 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0200081 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0198242 |
| TLN1 | talin 1 | 0.0197535 |
| ACTN4 | actinin, alpha 4 | 0.0195327 |
| RPS12 | ribosomal protein S12 | 0.0194481 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0194422 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0189096 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0188139 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0186415 |
| AXL | AXL receptor tyrosine kinase | 0.0185201 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0183426 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0181724 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0180188 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0179459 |
| B2M | beta-2-microglobulin | 0.0179435 |
| RPL32 | ribosomal protein L32 | 0.0178212 |
| CENPF | centromere protein F, 350/400kDa | 0.0175103 |
| ANXA2 | annexin A2 | 0.0172955 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.017256 |
| HELLS | helicase, lymphoid-specific | 0.0171768 |
| OGA | O-GlcNAcase | 0.0171161 |
| NFIA | nuclear factor I/A | 0.0171153 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0170397 |
| SATB2 | SATB homeobox 2 | 0.0170184 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0170156 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0169931 |
| YBX1 | Y box binding protein 1 | 0.0167989 |
| RPS19 | ribosomal protein S19 | 0.0167339 |
| FBXO32 | F-box protein 32 | 0.0165895 |
| CCNL1 | cyclin L1 | 0.0164619 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0164341 |
| RPLP2 | ribosomal protein, large, P2 | 0.0164278 |
| IPO7 | importin 7 | 0.0163548 |
| TPX2 | TPX2, microtubule-associated | 0.0163532 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0163028 |
| HMGB2 | high mobility group box 2 | 0.0162056 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0157605 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0157071 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0155253 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.015513 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.01547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.289869 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.246734 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.210195 |
| VIM | vimentin | -0.16822 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.126715 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.113493 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.110215 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.108266 |
| FBL | fibrillarin | -0.0971829 |
| PTMA | prothymosin, alpha | -0.0868603 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0847855 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0796357 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0712632 |
| RPL35A | ribosomal protein L35a | -0.0686944 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0668452 |
| AHNAK | AHNAK nucleoprotein | -0.0644118 |
| CANX | calnexin | -0.0614471 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0608031 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0595153 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0560501 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0487694 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0451517 |
| MYOF | myoferlin | -0.0439352 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0434377 |
| LDHA | lactate dehydrogenase A | -0.0425389 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.042459 |
| FMNL2 | formin-like 2 | -0.0414927 |
| MAP1B | microtubule-associated protein 1B | -0.0406853 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0405266 |
| TNS3 | tensin 3 | -0.0405174 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0402669 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0400824 |
| ADM | adrenomedullin | -0.0398986 |
| HMGA1 | high mobility group AT-hook 1 | -0.0386098 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0380898 |
| PKM | pyruvate kinase, muscle | -0.0375889 |
| PTK2 | protein tyrosine kinase 2 | -0.0374152 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0370993 |
| CTBP2 | C-terminal binding protein 2 | -0.0369182 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0368337 |
| NAV2 | neuron navigator 2 | -0.0366859 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0350135 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0348777 |
| FTL | ferritin, light polypeptide | -0.0340138 |
| CTSD | cathepsin D | -0.0338542 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0334573 |
| VEGFA | vascular endothelial growth factor A | -0.0331405 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0330066 |
| DIAPH2 | diaphanous-related formin 2 | -0.0327592 |
| EGFR | epidermal growth factor receptor | -0.0319001 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0314501 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0311296 |
| SEPTIN7 | septin 7 | -0.0296348 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0288112 |
| COPA | coatomer protein complex, subunit alpha | -0.0287209 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0285494 |
| HM13 | histocompatibility (minor) 13 | -0.0285388 |
| PGK1 | phosphoglycerate kinase 1 | -0.0282434 |
| SBF2 | SET binding factor 2 | -0.0281713 |
| AFAP1 | actin filament associated protein 1 | -0.0280734 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0280106 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0279026 |
| UPP1 | uridine phosphorylase 1 | -0.0276203 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0275004 |
| FBXO17 | F-box protein 17 | -0.026957 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0266681 |
| USP34 | ubiquitin specific peptidase 34 | -0.0266663 |
| CD109 | CD109 molecule | -0.0262565 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0256938 |
| TPM1 | tropomyosin 1 (alpha) | -0.0256179 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0255327 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.025458 |
| SPAG9 | sperm associated antigen 9 | -0.0252505 |
| GOLGA4 | golgin A4 | -0.0252318 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0248984 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0248702 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0248214 |
| S100A6 | S100 calcium binding protein A6 | -0.0247737 |
| POTEF | POTE ankyrin domain family, member F | -0.0246863 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0245452 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.024125 |
| ATG7 | autophagy related 7 | -0.0239841 |
| GOLGB1 | golgin B1 | -0.0239657 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0239448 |
| UBAP2 | ubiquitin associated protein 2 | -0.0237659 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0237183 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0236576 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0233648 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0231142 |
| MSN | moesin | -0.0229696 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0228329 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.022699 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0226658 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.022589 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0225281 |
| DST | dystonin | -0.0224853 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0224313 |
| CALR | calreticulin | -0.0223064 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0218814 |
| HMGA2 | high mobility group AT-hook 2 | -0.0218353 |
