| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0707018 |
| RPS2 | ribosomal protein S2 | 0.0444149 |
| MKI67 | marker of proliferation Ki-67 | 0.0426139 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0378403 |
| ANLN | anillin, actin binding protein | 0.0353134 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0329307 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0325016 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0310269 |
| DIAPH3 | diaphanous-related formin 3 | 0.0278582 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0257399 |
| LAMB3 | laminin, beta 3 | 0.025177 |
| CABIN1 | calcineurin binding protein 1 | 0.0246111 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0242345 |
| CENPF | centromere protein F, 350/400kDa | 0.0237081 |
| RPL21 | ribosomal protein L21 | 0.0233826 |
| RACK1 | receptor for activated C kinase 1 | 0.0228828 |
| TPI1 | triosephosphate isomerase 1 | 0.0226652 |
| GOLGA4 | golgin A4 | 0.022186 |
| HMGB2 | high mobility group box 2 | 0.0221095 |
| CCNL1 | cyclin L1 | 0.0218048 |
| RPL4 | ribosomal protein L4 | 0.0209616 |
| PNN | pinin, desmosome associated protein | 0.0208469 |
| TUBA1B | tubulin, alpha 1b | 0.0205452 |
| H1-4 | H1.4 linker histone, cluster member | 0.0200811 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0198622 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0195989 |
| FOSL1 | FOS-like antigen 1 | 0.0194461 |
| RPS12 | ribosomal protein S12 | 0.0186297 |
| WBP11 | WW domain binding protein 11 | 0.0181337 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0172888 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0171428 |
| RYK | receptor-like tyrosine kinase | 0.0168151 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0157871 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0157501 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0156092 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0155418 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0154873 |
| RPS8 | ribosomal protein S8 | 0.0152018 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0150846 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0145551 |
| SMAD3 | SMAD family member 3 | 0.0144921 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0144223 |
| RPL11 | ribosomal protein L11 | 0.0143208 |
| NAV2 | neuron navigator 2 | 0.0142433 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0138634 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0138315 |
| RPS19 | ribosomal protein S19 | 0.0138198 |
| RPL27 | ribosomal protein L27 | 0.0136155 |
| NOP58 | NOP58 ribonucleoprotein | 0.0134866 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0133534 |
| DTNA | dystrobrevin, alpha | 0.0132114 |
| RTN4 | reticulon 4 | 0.0129554 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0128278 |
| CCDC14 | coiled-coil domain containing 14 | 0.0127172 |
| ZNF292 | zinc finger protein 292 | 0.0125937 |
| RPS17 | ribosomal protein S17 | 0.0125718 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0123772 |
| GOLT1B | golgi transport 1B | 0.0123003 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0122242 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0120531 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0120342 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0120342 |
| TLN1 | talin 1 | 0.0120306 |
| EGR1 | early growth response 1 | 0.012026 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0119924 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0119689 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0119463 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0119427 |
| RPL18A | ribosomal protein L18a | 0.0118204 |
| TUBA1C | tubulin, alpha 1c | 0.0116393 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0115591 |
| RNF145 | ring finger protein 145 | 0.0115033 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0113878 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0112353 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0111998 |
| WDR43 | WD repeat domain 43 | 0.0111955 |
| FLNA | filamin A, alpha | 0.0110704 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0110489 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0109825 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0108557 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0107408 |
| RPS7 | ribosomal protein S7 | 0.0106525 |
| RPL35 | ribosomal protein L35 | 0.0105619 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.0105129 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0104375 |
| USP3 | ubiquitin specific peptidase 3 | 0.0104082 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0102852 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0102716 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0102668 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.010236 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.0102109 |
| GTF2B | general transcription factor IIB | 0.0102094 |
| RANBP1 | RAN binding protein 1 | 0.0101487 |
| FOXJ3 | forkhead box J3 | 0.0101004 |
| SLC44A2 | solute carrier family 44 (choline transporter), member 2 | 0.0100895 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0100701 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0100528 |
| UBQLN1 | ubiquilin 1 | 0.00999034 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.00994416 |
| UPP1 | uridine phosphorylase 1 | 0.00989983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.141943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.120744 |
| EMP1 | epithelial membrane protein 1 | -0.1127 |
| LAMA4 | laminin, alpha 4 | -0.109228 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.108304 |
| AHNAK | AHNAK nucleoprotein | -0.107526 |
| TMSB4X | thymosin beta 4, X-linked | -0.0983918 |
| KRT19 | keratin 19, type I | -0.0970461 |
| LDHA | lactate dehydrogenase A | -0.0931858 |
| TPM4 | tropomyosin 4 | -0.090767 |
| ANXA2 | annexin A2 | -0.0881814 |
| MUC4 | mucin 4, cell surface associated | -0.0877672 |
| ERBIN | erbb2 interacting protein | -0.0820585 |
| UBC | ubiquitin C | -0.081821 |
| CANX | calnexin | -0.0804425 |
| FN1 | fibronectin 1 | -0.0765006 |
| CD44 | CD44 molecule (Indian blood group) | -0.0739177 |
| ACTG1 | actin gamma 1 | -0.0735911 |
| KRT7 | keratin 7, type II | -0.0733971 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0713763 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.071302 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0685222 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0671658 |
| SVIL | supervillin | -0.0664151 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0662255 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0654336 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0651789 |
| MYO1E | myosin IE | -0.0651034 |
| TMSB10 | thymosin beta 10 | -0.0641003 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0634773 |
| POTEF | POTE ankyrin domain family, member F | -0.0620372 |
| CD2AP | CD2-associated protein | -0.0593224 |
| RNF213 | ring finger protein 213 | -0.058031 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0556505 |
| PTMA | prothymosin, alpha | -0.0554436 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0539201 |
| PLSCR1 | phospholipid scramblase 1 | -0.0539168 |
| MYOF | myoferlin | -0.0530168 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.052699 |
| DSG2 | desmoglein 2 | -0.0498747 |
| HMGA1 | high mobility group AT-hook 1 | -0.0495672 |
| B2M | beta-2-microglobulin | -0.0493988 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0488229 |
| ACTN4 | actinin, alpha 4 | -0.0486472 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0478992 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0477782 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0471775 |
| INTS6 | integrator complex subunit 6 | -0.0468312 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0463567 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.046268 |
| RPL23 | ribosomal protein L23 | -0.0458652 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0455311 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0454619 |
| C3 | complement component 3 | -0.0454494 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0453981 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0450452 |
| ASPH | aspartate beta-hydroxylase | -0.0446021 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0443423 |
| HLA-B | major histocompatibility complex, class I, B | -0.0437196 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0429535 |
| OSMR | oncostatin M receptor | -0.0425817 |
| RPS27A | ribosomal protein S27a | -0.0420321 |
| HLA-E | major histocompatibility complex, class I, E | -0.0419874 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0419197 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0417372 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0417297 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0412694 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0410287 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0402572 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0402075 |
| EZR | ezrin | -0.0397722 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0395834 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0391253 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0383537 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0378417 |
| MUC16 | mucin 16, cell surface associated | -0.0378189 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0378063 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0376527 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0375954 |
| TJP1 | tight junction protein 1 | -0.037276 |
| CD47 | CD47 molecule | -0.036904 |
| NDRG1 | N-myc downstream regulated 1 | -0.0369024 |
| S100A6 | S100 calcium binding protein A6 | -0.0367214 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0366448 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0364743 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0363983 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0357597 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0356218 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0354232 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0349772 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0343427 |
| GOLGB1 | golgin B1 | -0.0338481 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328499 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0323638 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0323578 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0321732 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0320785 |
| ETV6 | ets variant 6 | -0.0319776 |
| BPTF | bromodomain PHD finger transcription factor | -0.0318081 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.031773 |
