| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.176216 |
| RPS6 | ribosomal protein S6 | 0.0803646 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.069474 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.062289 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0597813 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0579053 |
| BCL2L1 | BCL2-like 1 | 0.0575901 |
| LAMB3 | laminin, beta 3 | 0.0560885 |
| PTMA | prothymosin, alpha | 0.0539186 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0528817 |
| RPS8 | ribosomal protein S8 | 0.0525575 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0503962 |
| RPL12 | ribosomal protein L12 | 0.0498256 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0497299 |
| RPS12 | ribosomal protein S12 | 0.0445124 |
| FTL | ferritin, light polypeptide | 0.0433631 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0424057 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0415114 |
| RPL7A | ribosomal protein L7a | 0.0407651 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0405789 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0401427 |
| RPL7 | ribosomal protein L7 | 0.0400864 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0389138 |
| RPS19 | ribosomal protein S19 | 0.0387743 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0386108 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0365389 |
| SRPK2 | SRSF protein kinase 2 | 0.0361965 |
| CCNL1 | cyclin L1 | 0.0360692 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0360577 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0359809 |
| RPL37A | ribosomal protein L37a | 0.0348449 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0344128 |
| RPL4 | ribosomal protein L4 | 0.0342796 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0338848 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0338569 |
| RPL8 | ribosomal protein L8 | 0.0334064 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0333999 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0333028 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.033026 |
| RPLP1 | ribosomal protein, large, P1 | 0.0328371 |
| RPL26 | ribosomal protein L26 | 0.0322276 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0321925 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.031642 |
| RBM39 | RNA binding motif protein 39 | 0.0308978 |
| RPL35A | ribosomal protein L35a | 0.0300738 |
| B2M | beta-2-microglobulin | 0.0299957 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0296284 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0286744 |
| RPS17 | ribosomal protein S17 | 0.0286162 |
| ZNF654 | zinc finger protein 654 | 0.0284933 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282596 |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 0.0277376 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0277198 |
| RPS2 | ribosomal protein S2 | 0.02755 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0270322 |
| TPM4 | tropomyosin 4 | 0.0269404 |
| TOP1 | topoisomerase (DNA) I | 0.0269089 |
| OGA | O-GlcNAcase | 0.0265399 |
| HLA-B | major histocompatibility complex, class I, B | 0.0262317 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0261905 |
| ASTN2 | astrotactin 2 | 0.0261677 |
| OLA1 | Obg-like ATPase 1 | 0.0259171 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0255712 |
| FBXO22 | F-box protein 22 | 0.0255327 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0252978 |
| RPL13A | ribosomal protein L13a | 0.0249687 |
| GNAS | GNAS complex locus | 0.0246489 |
| TNPO3 | transportin 3 | 0.0244361 |
| NUP58 | nucleoporin 58 | 0.0244195 |
| KIF5B | kinesin family member 5B | 0.024415 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0244002 |
| HLA-A | major histocompatibility complex, class I, A | 0.0243285 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0242299 |
| RPL11 | ribosomal protein L11 | 0.0240819 |
| RPS3 | ribosomal protein S3 | 0.0240017 |
| ATP13A3 | ATPase type 13A3 | 0.0239094 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0238604 |
| HELZ | helicase with zinc finger | 0.0238387 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0234435 |
| HMGB2 | high mobility group box 2 | 0.0231864 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0231508 |
| BBX | bobby sox homolog (Drosophila) | 0.0230582 |
| RPL35 | ribosomal protein L35 | 0.0228903 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0228639 |
| RPS13 | ribosomal protein S13 | 0.0228261 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0225391 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0223825 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0222996 |
| FRYL | FRY-like | 0.0219999 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0219765 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0219384 |
| RPL30 | ribosomal protein L30 | 0.0218622 |
| RPL32 | ribosomal protein L32 | 0.0217107 |
| MEF2A | myocyte enhancer factor 2A | 0.0213682 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.021337 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0212723 |
| RPS27 | ribosomal protein S27 | 0.0212558 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0211787 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0211424 |
| E2F7 | E2F transcription factor 7 | 0.0210198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.261854 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.226497 |
| NAV3 | neuron navigator 3 | -0.148899 |
| ZNF438 | zinc finger protein 438 | -0.141875 |
| FRMD6 | FERM domain containing 6 | -0.115097 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0979568 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0905069 |
| BNC2 | basonuclin 2 | -0.0870651 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0851425 |
| FRMD4A | FERM domain containing 4A | -0.0821074 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0812335 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0758554 |
| POTEF | POTE ankyrin domain family, member F | -0.0715378 |
| TTR | transthyretin | -0.0702998 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0697882 |
| NABP1 | nucleic acid binding protein 1 | -0.0687935 |
| ANK2 | ankyrin 2, neuronal | -0.0667845 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.063899 |
| DGKI | diacylglycerol kinase, iota | -0.0636728 |
| FLNB | filamin B, beta | -0.0603122 |
| FHIT | fragile histidine triad | -0.0572856 |
| SP100 | SP100 nuclear antigen | -0.0529296 |
| SMYD3 | SET and MYND domain containing 3 | -0.0499181 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0491371 |
| NAV2 | neuron navigator 2 | -0.0491178 |
| AGO2 | argonaute RISC catalytic component 2 | -0.048921 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0467964 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0458416 |
| ASPH | aspartate beta-hydroxylase | -0.0455479 |
| RAD51B | RAD51 paralog B | -0.0447614 |
| HMGA2 | high mobility group AT-hook 2 | -0.0442133 |
| JMJD1C | jumonji domain containing 1C | -0.0436414 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0434747 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0433256 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0418237 |
| DIAPH2 | diaphanous-related formin 2 | -0.0398827 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0398473 |
| HMGA1 | high mobility group AT-hook 1 | -0.0395514 |
| AHNAK | AHNAK nucleoprotein | -0.039488 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.039297 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0379914 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.037507 |
| MTAP | methylthioadenosine phosphorylase | -0.0366527 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0364997 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0361578 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0342841 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0329801 |
| EXT1 | exostosin glycosyltransferase 1 | -0.032679 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0320101 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0320025 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0316568 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0314261 |
| CALD1 | caldesmon 1 | -0.0312628 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310115 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0309924 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0307757 |
| SBF2 | SET binding factor 2 | -0.0306432 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0298248 |
| HDAC9 | histone deacetylase 9 | -0.0294654 |
| INTS6 | integrator complex subunit 6 | -0.0291689 |
| LDHA | lactate dehydrogenase A | -0.0280148 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0278632 |
| MYRFL | myelin regulatory factor-like | -0.0274579 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | -0.026876 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0267737 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0264967 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0264469 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0261215 |
| CCDC91 | coiled-coil domain containing 91 | -0.0260936 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.025986 |
| AEBP2 | AE binding protein 2 | -0.0254948 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0253894 |
| USP34 | ubiquitin specific peptidase 34 | -0.0250837 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0249249 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0246046 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0245145 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0243673 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0239522 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0235262 |
| MSH4 | mutS homolog 4 | -0.0233272 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0232491 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0231728 |
| DST | dystonin | -0.0222837 |
| RIGI | RNA sensor RIG-I | -0.0212597 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0212537 |
| MCL1 | myeloid cell leukemia 1 | -0.021035 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.020947 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | -0.020887 |
| CPQ | carboxypeptidase Q | -0.0207135 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0206042 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0204767 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0204404 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.020055 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0200398 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0199117 |
| ADTRP | androgen-dependent TFPI-regulating protein | -0.0197533 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0195785 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0195594 |
| CAPRIN2 | caprin family member 2 | -0.0195563 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0195249 |
