| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.111962 |
| CENPF | centromere protein F, 350/400kDa | 0.0920849 |
| VIM | vimentin | 0.0785215 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0706012 |
| ZNF292 | zinc finger protein 292 | 0.0665599 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0629881 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.062092 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0619517 |
| MKI67 | marker of proliferation Ki-67 | 0.0550744 |
| TPX2 | TPX2, microtubule-associated | 0.0516107 |
| RTN4 | reticulon 4 | 0.0510377 |
| ANLN | anillin, actin binding protein | 0.0499662 |
| TFG | TRK-fused gene | 0.0459649 |
| RBM39 | RNA binding motif protein 39 | 0.0454284 |
| GOLGA4 | golgin A4 | 0.0449648 |
| SEPTIN7 | septin 7 | 0.0448587 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0425322 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.042401 |
| XPO1 | exportin 1 | 0.0393065 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0385705 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.035237 |
| DIAPH3 | diaphanous-related formin 3 | 0.0351429 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0347096 |
| MSN | moesin | 0.0343824 |
| CENPE | centromere protein E, 312kDa | 0.0341616 |
| ECT2 | epithelial cell transforming 2 | 0.0337186 |
| H1-0 | H1.0 linker histone | 0.033358 |
| HMGB2 | high mobility group box 2 | 0.0320709 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0314547 |
| NOP58 | NOP58 ribonucleoprotein | 0.0312984 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0309984 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0309298 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0308818 |
| RNF24 | ring finger protein 24 | 0.030356 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0302423 |
| RNF145 | ring finger protein 145 | 0.0299526 |
| SGO2 | shugoshin 2 | 0.0298704 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0294393 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0293458 |
| SETD5 | SET domain containing 5 | 0.0288779 |
| OGA | O-GlcNAcase | 0.0286466 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0286068 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285367 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0284693 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0283992 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0278673 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0277203 |
| RPS6 | ribosomal protein S6 | 0.027641 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0275143 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0274299 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0269621 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268482 |
| DSTN | destrin (actin depolymerizing factor) | 0.026672 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.02658 |
| KIF4A | kinesin family member 4A | 0.0265046 |
| NUP58 | nucleoporin 58 | 0.0264137 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0257526 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.025713 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0256599 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0253208 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0252701 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0251718 |
| INSIG2 | insulin induced gene 2 | 0.0250484 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0245225 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0245079 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0244588 |
| YEATS2 | YEATS domain containing 2 | 0.0243072 |
| PCBP2 | poly(rC) binding protein 2 | 0.0242404 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0241616 |
| QKI | QKI, KH domain containing, RNA binding | 0.0241549 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0240298 |
| FAM13A | family with sequence similarity 13, member A | 0.0238668 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0237701 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.023714 |
| USP3 | ubiquitin specific peptidase 3 | 0.0236667 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0234018 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0233123 |
| KIF5B | kinesin family member 5B | 0.0232932 |
| YBX1 | Y box binding protein 1 | 0.023156 |
| PKM | pyruvate kinase, muscle | 0.0230273 |
| MATR3 | matrin 3 | 0.0230268 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0229505 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0227408 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.022554 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0225199 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0224876 |
| KIF20B | kinesin family member 20B | 0.0224819 |
| ZNF148 | zinc finger protein 148 | 0.022449 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0222377 |
| FOXJ3 | forkhead box J3 | 0.0221638 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0221433 |
| HELZ | helicase with zinc finger | 0.0220988 |
| RPS2 | ribosomal protein S2 | 0.0219832 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0218962 |
| TMF1 | TATA element modulatory factor 1 | 0.0218548 |
| PGK1 | phosphoglycerate kinase 1 | 0.0216992 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0215131 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0215026 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0213339 |
| TUBA1B | tubulin, alpha 1b | 0.0212969 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.215292 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.132606 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.130454 |
| COL1A2 | collagen, type I, alpha 2 | -0.128386 |
| B2M | beta-2-microglobulin | -0.126834 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.121739 |
| COL1A1 | collagen, type I, alpha 1 | -0.110623 |
| CDH13 | cadherin 13 | -0.0974099 |
| FTL | ferritin, light polypeptide | -0.0874577 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0839767 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0814648 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0797252 |
| SP100 | SP100 nuclear antigen | -0.0739912 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0737993 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0730415 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0706518 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0700818 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0692087 |
| IER3 | immediate early response 3 | -0.0674534 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.064972 |
| HLA-A | major histocompatibility complex, class I, A | -0.062912 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0617809 |
| HDAC9 | histone deacetylase 9 | -0.061775 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0609796 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0609248 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.060282 |
| ASPH | aspartate beta-hydroxylase | -0.0593744 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0586794 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0584152 |
| EGR1 | early growth response 1 | -0.0581638 |
| NAV1 | neuron navigator 1 | -0.0580349 |
| FN1 | fibronectin 1 | -0.0574433 |
| LOXL2 | lysyl oxidase-like 2 | -0.0563295 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.056167 |
| FAM20C | family with sequence similarity 20, member C | -0.0551478 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0545662 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0524551 |
| COL5A1 | collagen, type V, alpha 1 | -0.052006 |
| HLA-C | major histocompatibility complex, class I, C | -0.0502163 |
| IL1B | interleukin 1, beta | -0.0495916 |
| INHBA | inhibin, beta A | -0.0492934 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0461552 |
| FRMD4A | FERM domain containing 4A | -0.0457779 |
| NDRG1 | N-myc downstream regulated 1 | -0.0438832 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0438445 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0432871 |
| RPL35A | ribosomal protein L35a | -0.0432247 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0425044 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0420856 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0418037 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0414868 |
| SQSTM1 | sequestosome 1 | -0.0409475 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0405618 |
| TPM1 | tropomyosin 1 (alpha) | -0.0404345 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0404288 |
| GLIS3 | GLIS family zinc finger 3 | -0.0400086 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0398001 |
| HLA-E | major histocompatibility complex, class I, E | -0.039746 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0396836 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0395138 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0394651 |
| HPCAL1 | hippocalcin-like 1 | -0.0393848 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0392073 |
| ACTG1 | actin gamma 1 | -0.0389941 |
| INTS6 | integrator complex subunit 6 | -0.0384149 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0383513 |
| TMEM178B | transmembrane protein 178B | -0.0382814 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0382507 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0380944 |
| TNS3 | tensin 3 | -0.0379698 |
| FHIT | fragile histidine triad | -0.0379356 |
| EGFR | epidermal growth factor receptor | -0.0377879 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0374035 |
| RPL31 | ribosomal protein L31 | -0.0373503 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0371507 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0366755 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0363366 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0362617 |
| CADM1 | cell adhesion molecule 1 | -0.0361532 |
| MTSS1 | metastasis suppressor 1 | -0.0359836 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0352348 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0351899 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0351196 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0349179 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0345915 |
| VEGFA | vascular endothelial growth factor A | -0.0343576 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0338793 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0337533 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0337072 |
| COL5A3 | collagen, type V, alpha 3 | -0.033661 |
| SVIL | supervillin | -0.033313 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0327102 |
| VCL | vinculin | -0.0324543 |
| RAI14 | retinoic acid induced 14 | -0.0324119 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0323196 |
| NREP | neuronal regeneration related protein | -0.0322378 |
| TPM4 | tropomyosin 4 | -0.0313281 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0309772 |
| MCL1 | myeloid cell leukemia 1 | -0.0306643 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0306502 |
