| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.106316 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.05785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0485409 |
| CENPF | centromere protein F, 350/400kDa | 0.0385984 |
| XPO1 | exportin 1 | 0.0330366 |
| ZNF292 | zinc finger protein 292 | 0.0326758 |
| RPS2 | ribosomal protein S2 | 0.0313534 |
| PNN | pinin, desmosome associated protein | 0.0294224 |
| PTMA | prothymosin, alpha | 0.0266668 |
| USP3 | ubiquitin specific peptidase 3 | 0.025745 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0253611 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0249134 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0248076 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0243778 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0240252 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0239303 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0239295 |
| RBM25 | RNA binding motif protein 25 | 0.023718 |
| HMGB2 | high mobility group box 2 | 0.0228729 |
| PRKD1 | protein kinase D1 | 0.0228202 |
| TXNIP | thioredoxin interacting protein | 0.0225854 |
| MTMR7 | myotubularin related protein 7 | 0.0220795 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0220472 |
| RPL4 | ribosomal protein L4 | 0.0220353 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218373 |
| RPS12 | ribosomal protein S12 | 0.0216924 |
| RNF145 | ring finger protein 145 | 0.0215339 |
| SET | SET nuclear proto-oncogene | 0.0215271 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0208782 |
| MKI67 | marker of proliferation Ki-67 | 0.0207865 |
| TPM3 | tropomyosin 3 | 0.020369 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0201756 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0200574 |
| PBK | PDZ binding kinase | 0.019873 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0198538 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0196643 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0195557 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0194801 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0194227 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0191642 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.019155 |
| NFIA | nuclear factor I/A | 0.0188607 |
| TUBA1B | tubulin, alpha 1b | 0.0188587 |
| JAM3 | junctional adhesion molecule 3 | 0.0187599 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0187489 |
| SMAD9 | SMAD family member 9 | 0.0187234 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0185854 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0185746 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.018386 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0183671 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0183281 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0182401 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0182056 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0181532 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0181204 |
| H1-0 | H1.0 linker histone | 0.0181095 |
| MATR3 | matrin 3 | 0.0178492 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0176804 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0175613 |
| PCBP2 | poly(rC) binding protein 2 | 0.0174945 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0174913 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0174406 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0173813 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0173709 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.017329 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0170277 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0169991 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0169086 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0168187 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0167531 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.016588 |
| CENPC | centromere protein C | 0.0164693 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0161902 |
| AZIN1 | antizyme inhibitor 1 | 0.0161657 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.0158786 |
| FNBP1L | formin binding protein 1-like | 0.0158679 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.015805 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0157621 |
| NCKAP1 | NCK-associated protein 1 | 0.0156229 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.015597 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0155793 |
| ANLN | anillin, actin binding protein | 0.0155572 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0155449 |
| SFMBT2 | Scm-like with four mbt domains 2 | 0.0155394 |
| HELLS | helicase, lymphoid-specific | 0.0154467 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0154197 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0153649 |
| RDX | radixin | 0.0153391 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0152564 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0152539 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0152155 |
| USP24 | ubiquitin specific peptidase 24 | 0.0151535 |
| MEMO1 | mediator of cell motility 1 | 0.0150193 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0149351 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0149099 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0148927 |
| PER1 | period circadian clock 1 | 0.0148763 |
| RLF | rearranged L-myc fusion | 0.0148749 |
| RTN4 | reticulon 4 | 0.0148034 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0147823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | -0.145135 |
| NRG1 | neuregulin 1 | -0.144688 |
| MCL1 | myeloid cell leukemia 1 | -0.118105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.112942 |
| ACTG1 | actin gamma 1 | -0.109515 |
| NDRG1 | N-myc downstream regulated 1 | -0.103927 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0912601 |
| ENO1 | enolase 1, (alpha) | -0.0907197 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0893119 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0848439 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0836511 |
| NCKAP5 | NCK-associated protein 5 | -0.0773045 |
| RORA | RAR-related orphan receptor A | -0.0761126 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0752139 |
| STC1 | stanniocalcin 1 | -0.0747004 |
| KIF26B | kinesin family member 26B | -0.0745242 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0740931 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0670323 |
| CNKSR3 | CNKSR family member 3 | -0.0652217 |
| SNTG1 | syntrophin, gamma 1 | -0.0639587 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0630324 |
| CPE | carboxypeptidase E | -0.0619566 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0617336 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0613914 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0610708 |
| SCG2 | secretogranin II | -0.0602443 |
| CALCA | calcitonin-related polypeptide alpha | -0.0599188 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0596777 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0592138 |
| ESRRG | estrogen-related receptor gamma | -0.0559993 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0559888 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0544621 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.052545 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0524826 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.0503274 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0500122 |
| PTCHD4 | patched domain containing 4 | -0.0496409 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0493718 |
| SMYD3 | SET and MYND domain containing 3 | -0.0493598 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0490919 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0472265 |
| CHGA | chromogranin A | -0.0454428 |
| GPC5 | glypican 5 | -0.0446053 |
| MAP1B | microtubule-associated protein 1B | -0.0445683 |
| EGR1 | early growth response 1 | -0.0442843 |
| NAV2 | neuron navigator 2 | -0.0439163 |
| LSAMP | limbic system-associated membrane protein | -0.0436256 |
| FHIT | fragile histidine triad | -0.0434929 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0432944 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0425246 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0425118 |
| NBEA | neurobeachin | -0.042391 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0423737 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.042206 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.041026 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0407555 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0406188 |
| SETX | senataxin | -0.0397438 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0396485 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0386574 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0386299 |
| FGF14 | fibroblast growth factor 14 | -0.0379445 |
| RPL31 | ribosomal protein L31 | -0.0366315 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0365459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0361578 |
| CHGB | chromogranin B | -0.0358149 |
| EFNA5 | ephrin-A5 | -0.0356894 |
| SVIL | supervillin | -0.0355208 |
| HOMER1 | homer scaffolding protein 1 | -0.0353953 |
| IGF2 | insulin-like growth factor 2 | -0.0353516 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.035329 |
| NF1 | neurofibromin 1 | -0.0350273 |
| NAV1 | neuron navigator 1 | -0.0350069 |
| PGK1 | phosphoglycerate kinase 1 | -0.0346675 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.034515 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0343727 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.0340737 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.033943 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0339041 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0335211 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | -0.0334805 |
| SLC38A2 | solute carrier family 38, member 2 | -0.033049 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0328407 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0327291 |
| HM13 | histocompatibility (minor) 13 | -0.032647 |
| ARFGEF3 | ARFGEF family member 3 | -0.0325767 |
| MYT1L | myelin transcription factor 1-like | -0.0319803 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0316047 |
| POTEF | POTE ankyrin domain family, member F | -0.031468 |
| NELL1 | NEL-like 1 (chicken) | -0.0313549 |
| TOP1 | topoisomerase (DNA) I | -0.0313314 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0307459 |
| RPL23 | ribosomal protein L23 | -0.0307174 |
| SCFD1 | sec1 family domain containing 1 | -0.0304588 |
| RNF213 | ring finger protein 213 | -0.0300681 |
| CANX | calnexin | -0.0298356 |
| KLHL29 | kelch-like family member 29 | -0.0295561 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0293604 |
| RPL38 | ribosomal protein L38 | -0.0292313 |
| RPS25 | ribosomal protein S25 | -0.0289411 |
