| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.170129 |
| FNDC3B | fibronectin type III domain containing 3B | 0.152118 |
| FN1 | fibronectin 1 | 0.122582 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.118069 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.102857 |
| RPS3 | ribosomal protein S3 | 0.0830124 |
| MSI2 | musashi RNA-binding protein 2 | 0.0725625 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0701722 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0678694 |
| GOLGA4 | golgin A4 | 0.0636844 |
| RAD51B | RAD51 paralog B | 0.060395 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0600193 |
| CENPF | centromere protein F, 350/400kDa | 0.0571261 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0541771 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0511076 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0503175 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0466933 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0462468 |
| ANLN | anillin, actin binding protein | 0.0455362 |
| LSAMP | limbic system-associated membrane protein | 0.0444421 |
| SMAD3 | SMAD family member 3 | 0.0418823 |
| KAZN | kazrin, periplakin interacting protein | 0.0404469 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0401016 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0398698 |
| FHIT | fragile histidine triad | 0.0397733 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0395969 |
| SETD5 | SET domain containing 5 | 0.0395185 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.039506 |
| OGA | O-GlcNAcase | 0.039469 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0390267 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0389461 |
| PRELID2 | PRELI domain containing 2 | 0.0386453 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0377459 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0374718 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0373444 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0370642 |
| FLNA | filamin A, alpha | 0.0368081 |
| DENND1A | DENN/MADD domain containing 1A | 0.0367587 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0359241 |
| RPS2 | ribosomal protein S2 | 0.0357959 |
| RPL4 | ribosomal protein L4 | 0.035723 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0350383 |
| RNF145 | ring finger protein 145 | 0.0349871 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0345598 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0344423 |
| WAC | WW domain containing adaptor with coiled-coil | 0.033865 |
| PTMA | prothymosin, alpha | 0.0335784 |
| NGLY1 | N-glycanase 1 | 0.0335449 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0331488 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0328408 |
| MKI67 | marker of proliferation Ki-67 | 0.0326302 |
| ZNF292 | zinc finger protein 292 | 0.0319486 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0318166 |
| YEATS2 | YEATS domain containing 2 | 0.0317988 |
| RPS6 | ribosomal protein S6 | 0.031236 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0312219 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0307467 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0306945 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0306233 |
| CADM1 | cell adhesion molecule 1 | 0.0304557 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0300247 |
| TPM3 | tropomyosin 3 | 0.0295251 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0294887 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0294438 |
| TMF1 | TATA element modulatory factor 1 | 0.0291062 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0287878 |
| MMP12 | matrix metallopeptidase 12 | 0.028385 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0283614 |
| NRG3 | neuregulin 3 | 0.0283084 |
| TPI1 | triosephosphate isomerase 1 | 0.0282152 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0277569 |
| BBX | bobby sox homolog (Drosophila) | 0.0276008 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0275915 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0274761 |
| SPAG9 | sperm associated antigen 9 | 0.0274514 |
| RPS12 | ribosomal protein S12 | 0.0274083 |
| TNNC1 | troponin C type 1 (slow) | 0.0269982 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0266664 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0266617 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0265654 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0263919 |
| HELZ | helicase with zinc finger | 0.0263014 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0261656 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0261365 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0260677 |
| FAM13A | family with sequence similarity 13, member A | 0.0259864 |
| FNIP1 | folliculin interacting protein 1 | 0.0258253 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0252601 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0252208 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0251269 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0250978 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0250823 |
| MAP4 | microtubule-associated protein 4 | 0.0249091 |
| RTN4 | reticulon 4 | 0.0248987 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0246202 |
| RBM39 | RNA binding motif protein 39 | 0.0245076 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0245041 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0244537 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0244167 |
| SEPTIN9 | septin 9 | 0.024332 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.184496 |
| NLGN1 | neuroligin 1 | -0.100411 |
| FMN1 | formin 1 | -0.0744812 |
| TMSB10 | thymosin beta 10 | -0.0707004 |
| POTEF | POTE ankyrin domain family, member F | -0.0702678 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0651082 |
| CCND1 | cyclin D1 | -0.0599511 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0552886 |
| RPL35A | ribosomal protein L35a | -0.0535865 |
| RPLP1 | ribosomal protein, large, P1 | -0.0503198 |
| FTL | ferritin, light polypeptide | -0.048721 |
| MT1X | metallothionein 1X | -0.0484347 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0364969 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0357764 |
| NDRG1 | N-myc downstream regulated 1 | -0.0326807 |
| FRMD4A | FERM domain containing 4A | -0.0319747 |
| APOD | apolipoprotein D | -0.0318685 |
| ANGPTL4 | angiopoietin-like 4 | -0.0314968 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0313283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0297941 |
| ACTN4 | actinin, alpha 4 | -0.0295724 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0289178 |
| RPS13 | ribosomal protein S13 | -0.0285513 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0279661 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0277144 |
| RPL23 | ribosomal protein L23 | -0.027662 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0267877 |
| NOTCH2 | notch 2 | -0.0267828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266663 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0247012 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0242426 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0227484 |
| RPS21 | ribosomal protein S21 | -0.0225758 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0225457 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0222774 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.022194 |
| RPL38 | ribosomal protein L38 | -0.0217757 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0214904 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0214366 |
| ACTG1 | actin gamma 1 | -0.0211916 |
| RPS23 | ribosomal protein S23 | -0.0209907 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.020815 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0207884 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0207325 |
| USP34 | ubiquitin specific peptidase 34 | -0.0203337 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0202695 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.0202014 |
| CST3 | cystatin C | -0.0199854 |
| HLA-A | major histocompatibility complex, class I, A | -0.0198066 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0195536 |
| RPL19 | ribosomal protein L19 | -0.0195492 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0195019 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0191751 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0191494 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0188165 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0187794 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0185729 |
| HLA-B | major histocompatibility complex, class I, B | -0.0183506 |
| RPL34 | ribosomal protein L34 | -0.0182033 |
| PFN1 | profilin 1 | -0.0178878 |
| EPHA4 | EPH receptor A4 | -0.0171192 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0168162 |
| ATXN1 | ataxin 1 | -0.0167679 |
| S100A10 | S100 calcium binding protein A10 | -0.0167459 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.016696 |
| RPL9 | ribosomal protein L9 | -0.0166625 |
| TMEM117 | transmembrane protein 117 | -0.0166442 |
| CD63 | CD63 molecule | -0.0166181 |
| EMP1 | epithelial membrane protein 1 | -0.0166034 |
| NRXN3 | neurexin 3 | -0.0163819 |
| MAGT1 | magnesium transporter 1 | -0.0162117 |
| HMGA1 | high mobility group AT-hook 1 | -0.0161643 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.01615 |
| DIAPH1 | diaphanous-related formin 1 | -0.0160361 |
| CCNI | cyclin I | -0.0160273 |
| DCT | dopachrome tautomerase | -0.0159384 |
| DEK | DEK proto-oncogene | -0.0156687 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0155797 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0152798 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0151927 |
| UBAP2 | ubiquitin associated protein 2 | -0.0151403 |
| INTS6 | integrator complex subunit 6 | -0.0150392 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0150384 |
| FOSL1 | FOS-like antigen 1 | -0.0148885 |
| RPL27 | ribosomal protein L27 | -0.0148783 |
| MELTF | melanotransferrin | -0.0147227 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0146444 |
| DUSP6 | dual specificity phosphatase 6 | -0.0145691 |
| KIF5C | kinesin family member 5C | -0.0144756 |
| TUBB6 | tubulin, beta 6 class V | -0.0144624 |
| YIPF5 | Yip1 domain family, member 5 | -0.014353 |
| CALU | calumenin | -0.0143502 |
| ZNF652 | zinc finger protein 652 | -0.0142521 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0142423 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.014183 |
| RPS5 | ribosomal protein S5 | -0.0141184 |
| RPS10 | ribosomal protein S10 | -0.0140255 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0140146 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.013794 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0137448 |
