| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0901121 |
| EFNA5 | ephrin-A5 | 0.0687904 |
| RPS2 | ribosomal protein S2 | 0.0682432 |
| FLNA | filamin A, alpha | 0.0679142 |
| RPS12 | ribosomal protein S12 | 0.0678442 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0643759 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0636078 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0605205 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0591957 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.056336 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0505915 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0497805 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.048278 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0448692 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0410071 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0404599 |
| SFTPA2 | surfactant protein A2 | 0.0392533 |
| RPS8 | ribosomal protein S8 | 0.0387448 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0385396 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0374732 |
| CADM1 | cell adhesion molecule 1 | 0.0374413 |
| RPS3 | ribosomal protein S3 | 0.0372238 |
| RPL4 | ribosomal protein L4 | 0.03662 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0354732 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0350809 |
| HSPA8 | heat shock 70kDa protein 8 | 0.034972 |
| RPL37A | ribosomal protein L37a | 0.0338783 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0332139 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0325521 |
| HLA-A | major histocompatibility complex, class I, A | 0.0317247 |
| DIAPH3 | diaphanous-related formin 3 | 0.0311178 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0309229 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0307841 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0303313 |
| SMAD3 | SMAD family member 3 | 0.0302564 |
| RPL11 | ribosomal protein L11 | 0.0302343 |
| CDH13 | cadherin 13 | 0.0300583 |
| RACK1 | receptor for activated C kinase 1 | 0.02962 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0292707 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0291661 |
| INHBA | inhibin, beta A | 0.0290004 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0272921 |
| SRGN | serglycin | 0.0271438 |
| TPM3 | tropomyosin 3 | 0.0267719 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0267625 |
| RPS17 | ribosomal protein S17 | 0.0265522 |
| CALR | calreticulin | 0.0263746 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259828 |
| TUBA1B | tubulin, alpha 1b | 0.0257383 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0252005 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0251414 |
| RPS4X | ribosomal protein S4, X-linked | 0.0250471 |
| RPL26 | ribosomal protein L26 | 0.0249811 |
| RPL12 | ribosomal protein L12 | 0.0242762 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0242725 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0235631 |
| EGFR | epidermal growth factor receptor | 0.0235577 |
| ANLN | anillin, actin binding protein | 0.023309 |
| STC2 | stanniocalcin 2 | 0.0226576 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0224171 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.022281 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0213891 |
| PCBP2 | poly(rC) binding protein 2 | 0.0213218 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0212828 |
| CENPP | centromere protein P | 0.0212137 |
| TPI1 | triosephosphate isomerase 1 | 0.0206277 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0204374 |
| SDC4 | syndecan 4 | 0.0202624 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0201187 |
| RPL10A | ribosomal protein L10a | 0.0200279 |
| HELLS | helicase, lymphoid-specific | 0.0197666 |
| DTNA | dystrobrevin, alpha | 0.0196605 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0195173 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0194617 |
| XPO1 | exportin 1 | 0.019267 |
| HLA-B | major histocompatibility complex, class I, B | 0.0187669 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0186565 |
| YBX1 | Y box binding protein 1 | 0.017984 |
| MYLK | myosin light chain kinase | 0.0178331 |
| STC1 | stanniocalcin 1 | 0.0177402 |
| PRKCA | protein kinase C, alpha | 0.0177127 |
| AXL | AXL receptor tyrosine kinase | 0.0176052 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0175171 |
| NONO | non-POU domain containing, octamer-binding | 0.0173804 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0173634 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0173452 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.017258 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.017185 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0171692 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0170773 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0170684 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0169326 |
| UTRN | utrophin | 0.0168583 |
| BRCA1 | breast cancer 1, early onset | 0.0167782 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0167546 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0164069 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0163986 |
| RPL21 | ribosomal protein L21 | 0.0163877 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0163656 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0161767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.28712 |
| COL6A3 | collagen, type VI, alpha 3 | -0.111409 |
| VCL | vinculin | -0.107099 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104939 |
| VIM | vimentin | -0.104422 |
| PGK1 | phosphoglycerate kinase 1 | -0.0913498 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0881927 |
| BICC1 | BicC family RNA binding protein 1 | -0.0858436 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.075528 |
| VCAN | versican | -0.0752272 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0748686 |
| IER3 | immediate early response 3 | -0.0745706 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0734513 |
| FN1 | fibronectin 1 | -0.0683985 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0611739 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0577081 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.054476 |
| PDE10A | phosphodiesterase 10A | -0.0541953 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0536671 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0528481 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0526098 |
| NDRG1 | N-myc downstream regulated 1 | -0.0518796 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0504482 |
| LDHA | lactate dehydrogenase A | -0.0497922 |
| VEGFA | vascular endothelial growth factor A | -0.0490654 |
| TNS3 | tensin 3 | -0.0453252 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0452166 |
| NABP1 | nucleic acid binding protein 1 | -0.044355 |
| GLIS3 | GLIS family zinc finger 3 | -0.0442915 |
| ERBIN | erbb2 interacting protein | -0.0438049 |
| GPC6 | glypican 6 | -0.0434535 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0432838 |
| PLPP6 | phospholipid phosphatase 6 | -0.0424778 |
| DIAPH2 | diaphanous-related formin 2 | -0.041308 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0401208 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0396839 |
| JMJD1C | jumonji domain containing 1C | -0.0387826 |
| SBF2 | SET binding factor 2 | -0.0385797 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0367154 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0363869 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0361793 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0357777 |
| MX1 | MX dynamin-like GTPase 1 | -0.0349237 |
| VMP1 | vacuole membrane protein 1 | -0.034889 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0343096 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0343092 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.034141 |
| HDAC9 | histone deacetylase 9 | -0.0340034 |
| FRMD4A | FERM domain containing 4A | -0.0338163 |
| RAI14 | retinoic acid induced 14 | -0.0337951 |
| ADM | adrenomedullin | -0.0337274 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0336933 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0326746 |
| ZNF292 | zinc finger protein 292 | -0.0319069 |
| SP100 | SP100 nuclear antigen | -0.0315369 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0314834 |
| RPS24 | ribosomal protein S24 | -0.0314779 |
| AHNAK | AHNAK nucleoprotein | -0.031281 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0312714 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0308096 |
| PALLD | palladin, cytoskeletal associated protein | -0.0306239 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0305298 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0300446 |
| FOXO3 | forkhead box O3 | -0.029842 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0297473 |
| FLNB | filamin B, beta | -0.0297319 |
| ATXN1 | ataxin 1 | -0.029493 |
| RIGI | RNA sensor RIG-I | -0.0291888 |
| TPM4 | tropomyosin 4 | -0.0287651 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0285495 |
| DST | dystonin | -0.0283875 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0283502 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.028323 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0277839 |
| SETD5 | SET domain containing 5 | -0.027641 |
| MMP12 | matrix metallopeptidase 12 | -0.0273478 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0270954 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0270787 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0266811 |
| NAV2 | neuron navigator 2 | -0.0266591 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0265051 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0264951 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0264234 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0262321 |
| MYOF | myoferlin | -0.0261155 |
| FAM20C | family with sequence similarity 20, member C | -0.0260795 |
| PLIN2 | perilipin 2 | -0.0260077 |
| TXNIP | thioredoxin interacting protein | -0.0258058 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0257129 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.025656 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0256039 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0251269 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.024951 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0249072 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0248329 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0247984 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0246788 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0245895 |
| SMAD2 | SMAD family member 2 | -0.0244414 |
| ZNF207 | zinc finger protein 207 | -0.0243938 |
