| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.11967 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.116332 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0823469 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0810803 |
| FAM13A | family with sequence similarity 13, member A | 0.0793369 |
| NDRG1 | N-myc downstream regulated 1 | 0.0772412 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0744199 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0671599 |
| CDH13 | cadherin 13 | 0.06275 |
| CALR | calreticulin | 0.0572401 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0543248 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0515084 |
| COL5A1 | collagen, type V, alpha 1 | 0.0514201 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0500592 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.048781 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0479664 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0469856 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0463484 |
| SMYD3 | SET and MYND domain containing 3 | 0.0459971 |
| SEC24D | SEC24 family member D | 0.0456167 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.045159 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0431959 |
| FLNA | filamin A, alpha | 0.0419111 |
| NBAS | neuroblastoma amplified sequence | 0.0412719 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0399081 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0393005 |
| PTGES2 | prostaglandin E synthase 2 | 0.038919 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0387644 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0384037 |
| COG5 | component of oligomeric golgi complex 5 | 0.0366097 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.036524 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0362207 |
| RPS2 | ribosomal protein S2 | 0.0360083 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0358328 |
| SERINC1 | serine incorporator 1 | 0.0345294 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.034454 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0340103 |
| HMGB2 | high mobility group box 2 | 0.0339503 |
| HMGA2 | high mobility group AT-hook 2 | 0.0338014 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.03357 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0328514 |
| PTK2 | protein tyrosine kinase 2 | 0.0321192 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0320214 |
| IL6ST | interleukin 6 signal transducer | 0.0319926 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0319376 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0317651 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0317286 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0314759 |
| GSE1 | Gse1 coiled-coil protein | 0.0303817 |
| USP24 | ubiquitin specific peptidase 24 | 0.0297352 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0297217 |
| JMJD1C | jumonji domain containing 1C | 0.0296264 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0290837 |
| P3H1 | prolyl 3-hydroxylase 1 | 0.0290113 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0289687 |
| RAD51B | RAD51 paralog B | 0.0289036 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0288753 |
| TLK1 | tousled-like kinase 1 | 0.0286729 |
| SELENOF | selenoprotein F | 0.0286363 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0283636 |
| MATR3 | matrin 3 | 0.0283505 |
| AUTS2 | autism susceptibility candidate 2 | 0.0277601 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0275788 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273787 |
| FNIP1 | folliculin interacting protein 1 | 0.0271173 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0271101 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0269523 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0263596 |
| UBN2 | ubinuclein 2 | 0.026345 |
| MTREX | Mtr4 exosome RNA helicase | 0.0263332 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0263244 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0262698 |
| CANX | calnexin | 0.0258953 |
| GNAS | GNAS complex locus | 0.0258135 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0257822 |
| MED13L | mediator complex subunit 13-like | 0.02577 |
| PRKCA | protein kinase C, alpha | 0.0257604 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0256527 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0253919 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0253251 |
| ATP11B | ATPase, class VI, type 11B | 0.0251761 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.024924 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0248696 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0243118 |
| ANLN | anillin, actin binding protein | 0.02423 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0242185 |
| NRBP1 | nuclear receptor binding protein 1 | 0.0241195 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit | 0.0240981 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0239404 |
| DSTN | destrin (actin depolymerizing factor) | 0.0238874 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0238838 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0238552 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0237061 |
| CCNY | cyclin Y | 0.0236503 |
| PHF21A | PHD finger protein 21A | 0.0234713 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0234619 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0233556 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0232003 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.0231333 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0230758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.209917 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.157935 |
| TMSB10 | thymosin beta 10 | -0.150916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145175 |
| VIM | vimentin | -0.126291 |
| HLA-B | major histocompatibility complex, class I, B | -0.111293 |
| B2M | beta-2-microglobulin | -0.104754 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0879493 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0733761 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0726875 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0674757 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0634852 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0616821 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0612265 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0611991 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0596548 |
| ADM | adrenomedullin | -0.0570487 |
| CALD1 | caldesmon 1 | -0.0554028 |
| FNDC3A | fibronectin type III domain containing 3A | -0.055092 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0522865 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.052212 |
| VCL | vinculin | -0.049391 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0488726 |
| ARF4 | ADP-ribosylation factor 4 | -0.0480646 |
| LOX | lysyl oxidase | -0.0480115 |
| MAP1B | microtubule-associated protein 1B | -0.0473429 |
| TAGLN2 | transgelin 2 | -0.046454 |
| USP34 | ubiquitin specific peptidase 34 | -0.0460867 |
| PRSS23 | protease, serine, 23 | -0.0440211 |
| ACTG1 | actin gamma 1 | -0.0399942 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0398407 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0398057 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0389174 |
| PTMA | prothymosin, alpha | -0.0387823 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0387521 |
| LDHA | lactate dehydrogenase A | -0.0387469 |
| SDC4 | syndecan 4 | -0.0386186 |
| TPM4 | tropomyosin 4 | -0.0379228 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0377057 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0376065 |
| RPL35A | ribosomal protein L35a | -0.0374883 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0368552 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0362592 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0361256 |
| COL1A2 | collagen, type I, alpha 2 | -0.03582 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0353486 |
| NRP1 | neuropilin 1 | -0.0351184 |
| MRTFA | myocardin related transcription factor A | -0.0350762 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0345691 |
| RAI14 | retinoic acid induced 14 | -0.0344666 |
| CADM1 | cell adhesion molecule 1 | -0.0343355 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0337621 |
| TMEM87A | transmembrane protein 87A | -0.0337497 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.033749 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.033645 |
| RTN4 | reticulon 4 | -0.0328755 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0328596 |
| S100A6 | S100 calcium binding protein A6 | -0.0326559 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0322653 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0319308 |
| ASPH | aspartate beta-hydroxylase | -0.0317418 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.031691 |
| POTEF | POTE ankyrin domain family, member F | -0.031356 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0313206 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0306832 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0306067 |
| HIP1 | huntingtin interacting protein 1 | -0.0304302 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0301595 |
| TNS3 | tensin 3 | -0.0300217 |
| MYOF | myoferlin | -0.0299135 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0296609 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0296327 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.0296289 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0295046 |
| CDK6 | cyclin-dependent kinase 6 | -0.0294579 |
| INHBA | inhibin, beta A | -0.0293012 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0292415 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0291619 |
| CLTC | clathrin, heavy chain (Hc) | -0.0289215 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0279034 |
| GLIS3 | GLIS family zinc finger 3 | -0.0278497 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0277517 |
| SPAG9 | sperm associated antigen 9 | -0.0277099 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0276539 |
| RPL19 | ribosomal protein L19 | -0.0275399 |
| CD109 | CD109 molecule | -0.0266513 |
| AOPEP | aminopeptidase O (putative) | -0.0266115 |
| FN1 | fibronectin 1 | -0.0265117 |
| CALU | calumenin | -0.0264803 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0264772 |
| RPL36 | ribosomal protein L36 | -0.0264596 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0261487 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0260128 |
| TPM1 | tropomyosin 1 (alpha) | -0.0258146 |
| NABP1 | nucleic acid binding protein 1 | -0.0256382 |
| CD63 | CD63 molecule | -0.0255486 |
| TUT7 | terminal uridylyl transferase 7 | -0.0254578 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253699 |
| LMO7 | LIM domain 7 | -0.0252696 |
| FAT1 | FAT atypical cadherin 1 | -0.0249166 |
