| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.162544 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0890758 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0859954 |
| RPS6 | ribosomal protein S6 | 0.076514 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0663729 |
| VGF | VGF nerve growth factor inducible | 0.0621849 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0601541 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0586397 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.056209 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0535641 |
| CCNL1 | cyclin L1 | 0.0520104 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.05098 |
| RPL4 | ribosomal protein L4 | 0.0505715 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0461935 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0459181 |
| FLNA | filamin A, alpha | 0.0445536 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0432842 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0428347 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0386355 |
| SDC4 | syndecan 4 | 0.0362358 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0352109 |
| ZNF292 | zinc finger protein 292 | 0.0344803 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0339876 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0336282 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0331892 |
| RPL18 | ribosomal protein L18 | 0.0324154 |
| IFRD1 | interferon-related developmental regulator 1 | 0.032019 |
| PCBP2 | poly(rC) binding protein 2 | 0.0314956 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0310737 |
| SRPK2 | SRSF protein kinase 2 | 0.030767 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0304384 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0302027 |
| RPS2 | ribosomal protein S2 | 0.0301436 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.029751 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0291912 |
| VMP1 | vacuole membrane protein 1 | 0.0275646 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0271994 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0270565 |
| CAPN5 | calpain 5 | 0.0266126 |
| RPS12 | ribosomal protein S12 | 0.0262775 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0261792 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0255008 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0252672 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0251745 |
| RBM39 | RNA binding motif protein 39 | 0.0249947 |
| KIAA1671 | KIAA1671 | 0.0247952 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0247648 |
| TUBA1B | tubulin, alpha 1b | 0.024611 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0245962 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0245586 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0244889 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.023863 |
| SMAD3 | SMAD family member 3 | 0.0238317 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0238291 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0238119 |
| EGR1 | early growth response 1 | 0.0236467 |
| LMTK2 | lemur tyrosine kinase 2 | 0.023404 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0233023 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0231939 |
| RNF145 | ring finger protein 145 | 0.0230948 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0229557 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0229184 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0227642 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0227108 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0226504 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0225689 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0224607 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0224022 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0223726 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0222158 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0214795 |
| MXD1 | MAX dimerization protein 1 | 0.021406 |
| RIOK3 | RIO kinase 3 | 0.0212286 |
| MYO10 | myosin X | 0.0211724 |
| NDRG1 | N-myc downstream regulated 1 | 0.0210477 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.0210013 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020904 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0205418 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0202453 |
| USP3 | ubiquitin specific peptidase 3 | 0.0201246 |
| SFTPA2 | surfactant protein A2 | 0.0196729 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0196726 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0195064 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0192632 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0190407 |
| TGM2 | transglutaminase 2 | 0.0187601 |
| RPS17 | ribosomal protein S17 | 0.018735 |
| CLDN4 | claudin 4 | 0.0187021 |
| CTBP2 | C-terminal binding protein 2 | 0.0186487 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0186428 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0186414 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.01863 |
| CCNY | cyclin Y | 0.0183317 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0178571 |
| RPS3 | ribosomal protein S3 | 0.0178533 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.01771 |
| IPO7 | importin 7 | 0.0176578 |
| MYO18A | myosin XVIIIA | 0.0176312 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0175787 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0174299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.145259 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0906284 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0747044 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0678278 |
| ACTN4 | actinin, alpha 4 | -0.0642064 |
| PTMA | prothymosin, alpha | -0.0611807 |
| CANX | calnexin | -0.0604177 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0596033 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0580221 |
| FAT1 | FAT atypical cadherin 1 | -0.057945 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.05732 |
| GOLGA4 | golgin A4 | -0.0569656 |
| EPCAM | epithelial cell adhesion molecule | -0.0533617 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0529964 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0523724 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0522639 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0505628 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0504328 |
| RNF43 | ring finger protein 43 | -0.0489074 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0487372 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0472494 |
| CALU | calumenin | -0.0472149 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0470898 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0467379 |
| PKP4 | plakophilin 4 | -0.0462708 |
| CD46 | CD46 molecule, complement regulatory protein | -0.04585 |
| CST3 | cystatin C | -0.0457412 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0454178 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0453249 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0443413 |
| USP34 | ubiquitin specific peptidase 34 | -0.0435346 |
| TPM4 | tropomyosin 4 | -0.0433346 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0430649 |
| RPL35A | ribosomal protein L35a | -0.0424608 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0421673 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0420299 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0409716 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0395482 |
| RPL23 | ribosomal protein L23 | -0.0384368 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.038341 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0381112 |
| RPS21 | ribosomal protein S21 | -0.0375699 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0372761 |
| CCND1 | cyclin D1 | -0.0367949 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0363136 |
| STK4 | serine/threonine kinase 4 | -0.0362575 |
| PHF14 | PHD finger protein 14 | -0.0361512 |
| GPSM2 | G-protein signaling modulator 2 | -0.0360351 |
| CDCP1 | CUB domain containing protein 1 | -0.0353543 |
| HM13 | histocompatibility (minor) 13 | -0.0350635 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0349853 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0345885 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.034274 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0338169 |
| CENPF | centromere protein F, 350/400kDa | -0.0336213 |
| TMSB10 | thymosin beta 10 | -0.0334766 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0333969 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0330268 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0328522 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0324535 |
| PERP | PERP, TP53 apoptosis effector | -0.0324383 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.032249 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0321941 |
| RPS24 | ribosomal protein S24 | -0.0321041 |
| EHBP1 | EH domain binding protein 1 | -0.0317817 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0316379 |
| LDHA | lactate dehydrogenase A | -0.0313159 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0312546 |
| CDK13 | cyclin-dependent kinase 13 | -0.0311984 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0307583 |
| ANXA2 | annexin A2 | -0.0305281 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0304583 |
| KRT18 | keratin 18, type I | -0.0303994 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0303503 |
| DIAPH1 | diaphanous-related formin 1 | -0.0303473 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0303221 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296443 |
| DACH1 | dachshund family transcription factor 1 | -0.0292472 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0291359 |
| NRF1 | nuclear respiratory factor 1 | -0.0288988 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.028677 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0285744 |
| PLSCR1 | phospholipid scramblase 1 | -0.0284378 |
| SVIL | supervillin | -0.0280326 |
| ITGA6 | integrin, alpha 6 | -0.0278064 |
| NEBL | nebulette | -0.027785 |
| BCL2L1 | BCL2-like 1 | -0.0276961 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0272857 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0271947 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0270663 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0268114 |
| PTEN | phosphatase and tensin homolog | -0.0267719 |
| VCL | vinculin | -0.0266646 |
| FAM3C | family with sequence similarity 3, member C | -0.0266237 |
| POTEF | POTE ankyrin domain family, member F | -0.0266204 |
| UBAP2 | ubiquitin associated protein 2 | -0.0265801 |
| UBP1 | upstream binding protein 1 (LBP-1a) | -0.0265378 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0265162 |
| TLK1 | tousled-like kinase 1 | -0.0260365 |
| BPTF | bromodomain PHD finger transcription factor | -0.025828 |
