| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | 0.054644 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0458247 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0382764 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0331578 |
| RPS6 | ribosomal protein S6 | 0.0318738 |
| RPL4 | ribosomal protein L4 | 0.030929 |
| RPS12 | ribosomal protein S12 | 0.0257654 |
| RPS19 | ribosomal protein S19 | 0.0256026 |
| RPL13A | ribosomal protein L13a | 0.0214518 |
| FLNA | filamin A, alpha | 0.020669 |
| RPL26 | ribosomal protein L26 | 0.0199259 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0198964 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0198105 |
| RPL36 | ribosomal protein L36 | 0.019659 |
| RPS3 | ribosomal protein S3 | 0.0190433 |
| GDF15 | growth differentiation factor 15 | 0.01819 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0181387 |
| RPS27 | ribosomal protein S27 | 0.017317 |
| RPS17 | ribosomal protein S17 | 0.0168052 |
| LAMB3 | laminin, beta 3 | 0.0166994 |
| RPLP2 | ribosomal protein, large, P2 | 0.0159741 |
| RPL30 | ribosomal protein L30 | 0.0152873 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0150328 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0136994 |
| RPL32 | ribosomal protein L32 | 0.0135066 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0133093 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0132905 |
| TMF1 | TATA element modulatory factor 1 | 0.0132813 |
| RPL37A | ribosomal protein L37a | 0.0130031 |
| EPHA4 | EPH receptor A4 | 0.012803 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0127603 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0126619 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0123425 |
| RPS8 | ribosomal protein S8 | 0.011805 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0116904 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0115477 |
| ATOSA | atos homolog A | 0.011254 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0111792 |
| RPL37 | ribosomal protein L37 | 0.0110176 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0110067 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0109271 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0107026 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0103223 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0103075 |
| TMSB4X | thymosin beta 4, X-linked | 0.0101653 |
| RPS10 | ribosomal protein S10 | 0.010133 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0101201 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0100705 |
| MAP7D2 | MAP7 domain containing 2 | 0.00994717 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00987334 |
| POLH | polymerase (DNA directed), eta | 0.00987294 |
| RSRP1 | arginine/serine-rich protein 1 | 0.00976896 |
| ABHD3 | abhydrolase domain containing 3 | 0.00976397 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.00971168 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0096755 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00957168 |
| TRIP10 | thyroid hormone receptor interactor 10 | 0.00943517 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.00936317 |
| RPL21 | ribosomal protein L21 | 0.00934495 |
| RPS29 | ribosomal protein S29 | 0.00933171 |
| VIM | vimentin | 0.00930739 |
| ZNF451 | zinc finger protein 451 | 0.00925113 |
| ATN1 | atrophin 1 | 0.00925045 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00924972 |
| NTN1 | netrin 1 | 0.00921337 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0091115 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.00910688 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.00903088 |
| GOLT1B | golgi transport 1B | 0.008999 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.00878318 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0087679 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.00875963 |
| SMAP2 | small ArfGAP2 | 0.0086535 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.00854458 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00848165 |
| GOLGA2 | golgin A2 | 0.00843651 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | 0.00843045 |
| SEC61G | Sec61 gamma subunit | 0.00842808 |
| BRD4 | bromodomain containing 4 | 0.00834777 |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.00832148 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00825394 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.00824344 |
| SELENOI | selenoprotein I | 0.00823788 |
| SF1 | splicing factor 1 | 0.00814411 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00814354 |
| CPNE7 | copine VII | 0.00809214 |
| AGAP3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 | 0.0080818 |
| ERGIC3 | ERGIC and golgi 3 | 0.0079951 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 | 0.00794535 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00794428 |
| DHFR | dihydrofolate reductase | 0.00792557 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.00788073 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.0078088 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 0.00779928 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 0.00779605 |
| GRHL3 | grainyhead-like 3 (Drosophila) | 0.00779347 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.00775704 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00773456 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00769672 |
| GPS2 | G protein pathway suppressor 2 | 0.00766797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | -0.215464 |
| PTMA | prothymosin, alpha | -0.184061 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.135954 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133116 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.12354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.108104 |
| RAD51B | RAD51 paralog B | -0.105042 |
| EGFR | epidermal growth factor receptor | -0.0988573 |
| IER3 | immediate early response 3 | -0.0947306 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.090864 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0906523 |
| EZR | ezrin | -0.0877911 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0818761 |
| FHIT | fragile histidine triad | -0.0790452 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0753484 |
| ACTG1 | actin gamma 1 | -0.0751889 |
| ATXN1 | ataxin 1 | -0.0745142 |
| ANXA1 | annexin A1 | -0.0709185 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0708477 |
| HMGA2 | high mobility group AT-hook 2 | -0.0687864 |
| LDHA | lactate dehydrogenase A | -0.0666063 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0662825 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.06236 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0585881 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0566435 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0566312 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.054812 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0547082 |
| SNX9 | sorting nexin 9 | -0.0530456 |
| GPHN | gephyrin | -0.0486625 |
| ANXA2 | annexin A2 | -0.0486379 |
| PARD3 | par-3 family cell polarity regulator | -0.0485265 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0459523 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0455899 |
| FERMT1 | fermitin family member 1 | -0.0447114 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0437457 |
| OXR1 | oxidation resistance 1 | -0.0437305 |
| TMSB10 | thymosin beta 10 | -0.0428239 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.042751 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0426638 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0423069 |
| HDAC2 | histone deacetylase 2 | -0.0419244 |
| LMO7 | LIM domain 7 | -0.0417086 |
| CUX1 | cut-like homeobox 1 | -0.0412667 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0409421 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0408378 |
| FAT1 | FAT atypical cadherin 1 | -0.0403911 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0403012 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0399938 |
| CLTC | clathrin, heavy chain (Hc) | -0.0385369 |
| CPOX | coproporphyrinogen oxidase | -0.0383505 |
| ACTN4 | actinin, alpha 4 | -0.0372107 |
| ZNF292 | zinc finger protein 292 | -0.0367683 |
| FOSL1 | FOS-like antigen 1 | -0.0363695 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.036043 |
| PHF14 | PHD finger protein 14 | -0.035852 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.035629 |
| RCOR1 | REST corepressor 1 | -0.0354471 |
| CENPF | centromere protein F, 350/400kDa | -0.0353891 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0353672 |
| SMYD3 | SET and MYND domain containing 3 | -0.0353656 |
| KITLG | KIT ligand | -0.0345585 |
| ECT2 | epithelial cell transforming 2 | -0.0344407 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0343377 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0343281 |
| MKI67 | marker of proliferation Ki-67 | -0.0342969 |
| TPM4 | tropomyosin 4 | -0.0339488 |
| TXNIP | thioredoxin interacting protein | -0.0334631 |
| TMEM123 | transmembrane protein 123 | -0.0333991 |
| RBM25 | RNA binding motif protein 25 | -0.0332739 |
| RPL35A | ribosomal protein L35a | -0.0329603 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0328589 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0326533 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0326241 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0322523 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0320479 |
| DIAPH2 | diaphanous-related formin 2 | -0.0319074 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0318916 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0317935 |
| USP3 | ubiquitin specific peptidase 3 | -0.0312366 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0312159 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0311528 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0308465 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0305726 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0305455 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0304563 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0304256 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0304165 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0302318 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301488 |
| DEK | DEK proto-oncogene | -0.0301449 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0301313 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0297546 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.029434 |
| FAM3C | family with sequence similarity 3, member C | -0.0293364 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0292992 |
| RPL23 | ribosomal protein L23 | -0.0289294 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0289194 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0287727 |
| VCL | vinculin | -0.0287458 |
