| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0910354 |
| MKI67 | marker of proliferation Ki-67 | 0.0591539 |
| RPS2 | ribosomal protein S2 | 0.0498713 |
| PCBP2 | poly(rC) binding protein 2 | 0.0440591 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0429914 |
| PNN | pinin, desmosome associated protein | 0.0427627 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0423952 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401745 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0401584 |
| RPS6 | ribosomal protein S6 | 0.0396804 |
| DIAPH3 | diaphanous-related formin 3 | 0.0393026 |
| RPS12 | ribosomal protein S12 | 0.0389743 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0379257 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0375646 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0351477 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0349144 |
| NHSL1 | NHS-like 1 | 0.0347556 |
| HELLS | helicase, lymphoid-specific | 0.0342468 |
| TUBA1B | tubulin, alpha 1b | 0.0334141 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0317346 |
| RPL4 | ribosomal protein L4 | 0.0315476 |
| RAD51B | RAD51 paralog B | 0.0310055 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0305779 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0298781 |
| TPM3 | tropomyosin 3 | 0.0296951 |
| WWOX | WW domain containing oxidoreductase | 0.0295027 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0291647 |
| FANCI | Fanconi anemia, complementation group I | 0.0290466 |
| YBX1 | Y box binding protein 1 | 0.0290296 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0284697 |
| TPI1 | triosephosphate isomerase 1 | 0.0281284 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0275064 |
| CENPF | centromere protein F, 350/400kDa | 0.0273695 |
| UTRN | utrophin | 0.0270756 |
| EXOC4 | exocyst complex component 4 | 0.0258209 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0254866 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0252711 |
| TPP2 | tripeptidyl peptidase II | 0.0249224 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0240253 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0240091 |
| PRKCA | protein kinase C, alpha | 0.0239497 |
| FLNA | filamin A, alpha | 0.0238339 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0236522 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234994 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0231217 |
| CBX5 | chromobox homolog 5 | 0.0228796 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0227112 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0225367 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0219768 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0217672 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.021688 |
| FANCL | Fanconi anemia, complementation group L | 0.0212894 |
| XPO1 | exportin 1 | 0.0212332 |
| RRM2 | ribonucleotide reductase M2 | 0.0211952 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0209391 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0208418 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0208111 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0200928 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0200904 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0199736 |
| CDK19 | cyclin-dependent kinase 19 | 0.0199224 |
| VRK1 | vaccinia related kinase 1 | 0.0198845 |
| RAD51AP1 | RAD51 associated protein 1 | 0.019721 |
| CEP128 | centrosomal protein 128kDa | 0.0196992 |
| ATAD5 | ATPase family, AAA domain containing 5 | 0.0196905 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0195093 |
| IPO7 | importin 7 | 0.0194563 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0193574 |
| TLN1 | talin 1 | 0.0191096 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0189713 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0189546 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0186246 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.01859 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0185341 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.018275 |
| STK38L | serine/threonine kinase 38 like | 0.018229 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0181884 |
| CENPP | centromere protein P | 0.0180565 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | 0.0180137 |
| CLSPN | claspin | 0.0180013 |
| BRCA1 | breast cancer 1, early onset | 0.0179487 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0179202 |
| MSN | moesin | 0.0178736 |
| MCM8 | minichromosome maintenance complex component 8 | 0.0178344 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0178307 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0178024 |
| MMS22L | MMS22-like, DNA repair protein | 0.0176112 |
| RPL21 | ribosomal protein L21 | 0.0174934 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0171159 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0170544 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0170307 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0168002 |
| KNTC1 | kinetochore associated 1 | 0.0167988 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0167915 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.016676 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0166119 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0165183 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0164395 |
| CCDC14 | coiled-coil domain containing 14 | 0.0163285 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0163002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.186913 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.14569 |
| EZR | ezrin | -0.133511 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.123345 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115108 |
| ANXA2 | annexin A2 | -0.111323 |
| RPL35A | ribosomal protein L35a | -0.106895 |
| INTS6 | integrator complex subunit 6 | -0.101913 |
| VCL | vinculin | -0.100728 |
| ACTG1 | actin gamma 1 | -0.0838376 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.079596 |
| TMSB10 | thymosin beta 10 | -0.0746335 |
| RPS24 | ribosomal protein S24 | -0.0739864 |
| PGK1 | phosphoglycerate kinase 1 | -0.072025 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0689813 |
| KRT18 | keratin 18, type I | -0.0676577 |
| AHNAK | AHNAK nucleoprotein | -0.065077 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.062745 |
| RPL23 | ribosomal protein L23 | -0.0622955 |
| RPLP1 | ribosomal protein, large, P1 | -0.0610359 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0601546 |
| ACTN4 | actinin, alpha 4 | -0.060016 |
| MORF4L2 | mortality factor 4 like 2 | -0.057434 |
| ENO1 | enolase 1, (alpha) | -0.0573183 |
| EMP1 | epithelial membrane protein 1 | -0.0556462 |
| TPM4 | tropomyosin 4 | -0.0528772 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0522593 |
| LDHA | lactate dehydrogenase A | -0.0520933 |
| S100A10 | S100 calcium binding protein A10 | -0.0499814 |
| GOLGA4 | golgin A4 | -0.0493105 |
| CCND1 | cyclin D1 | -0.0476098 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0445113 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0439859 |
| LMO7 | LIM domain 7 | -0.0434954 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0432636 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0432148 |
| PTMA | prothymosin, alpha | -0.0424396 |
| CANX | calnexin | -0.0419918 |
| RPLP0 | ribosomal protein, large, P0 | -0.0418838 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0415745 |
| ASPH | aspartate beta-hydroxylase | -0.0406137 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0403764 |
| RPL19 | ribosomal protein L19 | -0.0400901 |
| ATXN1 | ataxin 1 | -0.0394835 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0394815 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.038942 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0387328 |
| ARF4 | ADP-ribosylation factor 4 | -0.0385651 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0384916 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0383705 |
| FTL | ferritin, light polypeptide | -0.0383153 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0382646 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.038105 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.037553 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0374034 |
| RPS5 | ribosomal protein S5 | -0.03731 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0369093 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0368884 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0367648 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0359438 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0357899 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.035303 |
| MT2A | metallothionein 2A | -0.0351892 |
| RPS13 | ribosomal protein S13 | -0.035181 |
| KRT8 | keratin 8, type II | -0.0350656 |
| EFNB2 | ephrin-B2 | -0.0349357 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.034721 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.034572 |
| RPL31 | ribosomal protein L31 | -0.0345236 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.034399 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0342045 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0335181 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0329774 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0324136 |
| NDRG1 | N-myc downstream regulated 1 | -0.0319163 |
| RPS27A | ribosomal protein S27a | -0.03159 |
| RPS25 | ribosomal protein S25 | -0.0314212 |
| RPS21 | ribosomal protein S21 | -0.0313755 |
| DUSP6 | dual specificity phosphatase 6 | -0.0312158 |
| USP34 | ubiquitin specific peptidase 34 | -0.0308339 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0298495 |
| RPS8 | ribosomal protein S8 | -0.029721 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0296699 |
| MYOF | myoferlin | -0.0296527 |
| IER3 | immediate early response 3 | -0.0295981 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293105 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0292923 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0291351 |
| RPL34 | ribosomal protein L34 | -0.0284174 |
| RPL12 | ribosomal protein L12 | -0.0283047 |
| NEBL | nebulette | -0.0281475 |
| PERP | PERP, TP53 apoptosis effector | -0.0279984 |
| HDLBP | high density lipoprotein binding protein | -0.0278489 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.02782 |
| FLNB | filamin B, beta | -0.0275449 |
| MYO1E | myosin IE | -0.0274043 |
| KRT19 | keratin 19, type I | -0.0271115 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0270853 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0270704 |
| RPL27A | ribosomal protein L27a | -0.0270332 |
