| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Epirubicin (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.11485 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0994031 |
| RPS6 | ribosomal protein S6 | 0.0848513 |
| MT2A | metallothionein 2A | 0.0657691 |
| RPS12 | ribosomal protein S12 | 0.053299 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.049777 |
| RPL37A | ribosomal protein L37a | 0.0454373 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0425554 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0415665 |
| RPS8 | ribosomal protein S8 | 0.0411144 |
| HLA-B | major histocompatibility complex, class I, B | 0.0405144 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0396429 |
| RPS19 | ribosomal protein S19 | 0.0388785 |
| B2M | beta-2-microglobulin | 0.0369711 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0362601 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.036253 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0359 |
| FTL | ferritin, light polypeptide | 0.0342174 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0316534 |
| RPS2 | ribosomal protein S2 | 0.03073 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0285869 |
| OGA | O-GlcNAcase | 0.027651 |
| FLNA | filamin A, alpha | 0.027556 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0269963 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0267936 |
| RACK1 | receptor for activated C kinase 1 | 0.0265749 |
| RPLP1 | ribosomal protein, large, P1 | 0.0265153 |
| RPS3 | ribosomal protein S3 | 0.0258378 |
| RPL4 | ribosomal protein L4 | 0.0258236 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0256582 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0252257 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0250677 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.024967 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0246696 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0246298 |
| YBX1 | Y box binding protein 1 | 0.0243126 |
| CCNL1 | cyclin L1 | 0.0238809 |
| STC1 | stanniocalcin 1 | 0.0236721 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0232387 |
| RPS17 | ribosomal protein S17 | 0.0230846 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0228551 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0224133 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0220435 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0218872 |
| RPL12 | ribosomal protein L12 | 0.0217934 |
| RPL26 | ribosomal protein L26 | 0.0217464 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0215877 |
| RPL34 | ribosomal protein L34 | 0.0211205 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.021056 |
| AXL | AXL receptor tyrosine kinase | 0.0206506 |
| PTMA | prothymosin, alpha | 0.0206137 |
| HMGB2 | high mobility group box 2 | 0.0205446 |
| RPL9 | ribosomal protein L9 | 0.0203384 |
| RPL28 | ribosomal protein L28 | 0.0201951 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0200068 |
| RPL35A | ribosomal protein L35a | 0.0200062 |
| RPL31 | ribosomal protein L31 | 0.0199047 |
| RPL5 | ribosomal protein L5 | 0.0198942 |
| RPL13A | ribosomal protein L13a | 0.0198446 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0196334 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.019597 |
| RPS23 | ribosomal protein S23 | 0.0195891 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0195488 |
| RPL23 | ribosomal protein L23 | 0.0193383 |
| MEIS1 | Meis homeobox 1 | 0.0189816 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0186789 |
| RASA2 | RAS p21 protein activator 2 | 0.01863 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0186255 |
| TPI1 | triosephosphate isomerase 1 | 0.0184741 |
| RPS27L | ribosomal protein S27-like | 0.018176 |
| RPL36 | ribosomal protein L36 | 0.0179439 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0178979 |
| YBX3 | Y box binding protein 3 | 0.0176856 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0176789 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0176692 |
| NOP58 | NOP58 ribonucleoprotein | 0.0176002 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0174426 |
| BRD2 | bromodomain containing 2 | 0.0170314 |
| RPL37 | ribosomal protein L37 | 0.0167168 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0167135 |
| RPL27 | ribosomal protein L27 | 0.0166487 |
| FAM13A | family with sequence similarity 13, member A | 0.0164655 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0164159 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0163966 |
| RPL32 | ribosomal protein L32 | 0.0162465 |
| RPL19 | ribosomal protein L19 | 0.016236 |
| RPS4X | ribosomal protein S4, X-linked | 0.0161592 |
| EGR1 | early growth response 1 | 0.0156543 |
| RPL35 | ribosomal protein L35 | 0.0155891 |
| RPL21 | ribosomal protein L21 | 0.0155443 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155376 |
| IPO7 | importin 7 | 0.0154069 |
| ZNF638 | zinc finger protein 638 | 0.0152299 |
| RPL18 | ribosomal protein L18 | 0.0151728 |
| FMNL2 | formin-like 2 | 0.0151687 |
| NOTCH2 | notch 2 | 0.0151433 |
| IL6 | interleukin 6 | 0.0149689 |
| RPL7 | ribosomal protein L7 | 0.0147177 |
| RPS16 | ribosomal protein S16 | 0.0142988 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.014204 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.362173 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.179413 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.177061 |
| COL1A1 | collagen, type I, alpha 1 | -0.165128 |
| FN1 | fibronectin 1 | -0.144923 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.1355 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.11621 |
| HMGA2 | high mobility group AT-hook 2 | -0.106987 |
| COL1A2 | collagen, type I, alpha 2 | -0.09696 |
| FBN1 | fibrillin 1 | -0.096403 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0870412 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0713731 |
| AHNAK | AHNAK nucleoprotein | -0.0706389 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.069963 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0676906 |
| RAI14 | retinoic acid induced 14 | -0.0665258 |
| LOX | lysyl oxidase | -0.0647423 |
| OXR1 | oxidation resistance 1 | -0.0647057 |
| VIM | vimentin | -0.0627953 |
| MAP1B | microtubule-associated protein 1B | -0.0595633 |
| EMP1 | epithelial membrane protein 1 | -0.0588636 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0570986 |
| DST | dystonin | -0.0549391 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0548427 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0530051 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0523338 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0512749 |
| ATP13A3 | ATPase type 13A3 | -0.0512516 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0511831 |
| NAV1 | neuron navigator 1 | -0.0500737 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0483893 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0474476 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.046616 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0448406 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0444816 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0441023 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0433588 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0428869 |
| MMP1 | matrix metallopeptidase 1 | -0.0428307 |
| MMP12 | matrix metallopeptidase 12 | -0.0422961 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0409893 |
| DIAPH2 | diaphanous-related formin 2 | -0.0408811 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0403724 |
| CAVIN1 | caveolae associated protein 1 | -0.0398434 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0390243 |
| FRMD4A | FERM domain containing 4A | -0.038067 |
| GLIS3 | GLIS family zinc finger 3 | -0.0378943 |
| PRSS23 | protease, serine, 23 | -0.0369497 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.036687 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0362287 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0361839 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0361395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0353468 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0348296 |
| COL5A1 | collagen, type V, alpha 1 | -0.034787 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0344358 |
| CCND1 | cyclin D1 | -0.0339855 |
| PGK1 | phosphoglycerate kinase 1 | -0.0333634 |
| CALD1 | caldesmon 1 | -0.0330705 |
| HHIP | hedgehog interacting protein | -0.0326317 |
| ATM | ATM serine/threonine kinase | -0.0325232 |
| INHBA | inhibin, beta A | -0.0321124 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0321096 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.031765 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0314878 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0311644 |
| PRRX1 | paired related homeobox 1 | -0.0309832 |
| COL6A1 | collagen, type VI, alpha 1 | -0.030926 |
| CDH13 | cadherin 13 | -0.0308735 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0304199 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0303064 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0301411 |
| CANX | calnexin | -0.0300775 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.029071 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -0.0289949 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0288571 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0284967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.028061 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0278234 |
| LOXL2 | lysyl oxidase-like 2 | -0.0273743 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0273583 |
| COL5A3 | collagen, type V, alpha 3 | -0.0271722 |
| EHBP1 | EH domain binding protein 1 | -0.0268904 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0268164 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0268084 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0266849 |
| RASAL2 | RAS protein activator like 2 | -0.0263116 |
| TPM4 | tropomyosin 4 | -0.0262992 |
| ITGA11 | integrin, alpha 11 | -0.0257471 |
| MYO10 | myosin X | -0.0255722 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.025571 |
| FOXP1 | forkhead box P1 | -0.0251681 |
| TPM1 | tropomyosin 1 (alpha) | -0.0250941 |
| LDHA | lactate dehydrogenase A | -0.0249676 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0246663 |
| TCF12 | transcription factor 12 | -0.024531 |
| ASPH | aspartate beta-hydroxylase | -0.0244118 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0243435 |
| EXT1 | exostosin glycosyltransferase 1 | -0.024267 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0241953 |
