| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.108799 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.102773 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0836358 |
| COL5A1 | collagen, type V, alpha 1 | 0.0826181 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0791822 |
| AHNAK | AHNAK nucleoprotein | 0.0735756 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0684805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0569203 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0504006 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0458501 |
| LOX | lysyl oxidase | 0.0438071 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0431512 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0428365 |
| FBN1 | fibrillin 1 | 0.041707 |
| SEPTIN9 | septin 9 | 0.0408759 |
| POTEF | POTE ankyrin domain family, member F | 0.0407861 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0400164 |
| COL5A2 | collagen, type V, alpha 2 | 0.0383985 |
| CDH13 | cadherin 13 | 0.0360707 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.035379 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0345747 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0340135 |
| CALR | calreticulin | 0.0337256 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0332761 |
| NAV1 | neuron navigator 1 | 0.0320805 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0313652 |
| HIP1 | huntingtin interacting protein 1 | 0.0309516 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0304246 |
| DST | dystonin | 0.0303296 |
| LOXL2 | lysyl oxidase-like 2 | 0.0300044 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0297534 |
| ATP13A3 | ATPase type 13A3 | 0.0296325 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294677 |
| NAV2 | neuron navigator 2 | 0.0277084 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0274748 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0267829 |
| THBS2 | thrombospondin 2 | 0.0260298 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0259428 |
| COPA | coatomer protein complex, subunit alpha | 0.0257034 |
| SPAG9 | sperm associated antigen 9 | 0.0254993 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0254635 |
| CANX | calnexin | 0.0252428 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.025029 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0241473 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.023773 |
| MSI2 | musashi RNA-binding protein 2 | 0.023742 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0237114 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.023552 |
| PLEC | plectin | 0.0232649 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0227899 |
| C1D | C1D nuclear receptor corepressor | 0.022616 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0221515 |
| EGFR | epidermal growth factor receptor | 0.0214388 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0212099 |
| VEGFA | vascular endothelial growth factor A | 0.0211546 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0207102 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.020673 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0206239 |
| DENND5A | DENN/MADD domain containing 5A | 0.0205581 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0204882 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0203259 |
| TPM3 | tropomyosin 3 | 0.0198328 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0197289 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0194168 |
| FLNA | filamin A, alpha | 0.0193814 |
| GOLGA2 | golgin A2 | 0.0189851 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0182629 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0182182 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0181305 |
| RASA3 | RAS p21 protein activator 3 | 0.0181144 |
| CEP170 | centrosomal protein 170kDa | 0.0177312 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.017609 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0172685 |
| FNIP1 | folliculin interacting protein 1 | 0.0172587 |
| AUTS2 | autism susceptibility candidate 2 | 0.0172244 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0171306 |
| GOLGB1 | golgin B1 | 0.0169792 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0169135 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0167804 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0162935 |
| CTBP2 | C-terminal binding protein 2 | 0.0160443 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0158948 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0158333 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0158159 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0157821 |
| UBC | ubiquitin C | 0.0157229 |
| TAOK1 | TAO kinase 1 | 0.015691 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.015619 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0155116 |
| SQSTM1 | sequestosome 1 | 0.0154181 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0153695 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0153558 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0153499 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0152894 |
| FLNB | filamin B, beta | 0.015239 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0150133 |
| JAZF1 | JAZF zinc finger 1 | 0.0149489 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0149233 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0149166 |
| INSIG2 | insulin induced gene 2 | 0.0149159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.249157 |
| TMSB10 | thymosin beta 10 | -0.236045 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188673 |
| VIM | vimentin | -0.156302 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.105069 |
| HLA-B | major histocompatibility complex, class I, B | -0.0672999 |
| NDRG1 | N-myc downstream regulated 1 | -0.065807 |
| S100A10 | S100 calcium binding protein A10 | -0.0571395 |
| MT1X | metallothionein 1X | -0.054277 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0542009 |
| CD44 | CD44 molecule (Indian blood group) | -0.0502807 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0454774 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437649 |
| FTL | ferritin, light polypeptide | -0.0428511 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0411291 |
| PLAT | plasminogen activator, tissue | -0.0406193 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.037975 |
| RPS19 | ribosomal protein S19 | -0.0378153 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.036463 |
| RPLP2 | ribosomal protein, large, P2 | -0.0362887 |
| S100A11 | S100 calcium binding protein A11 | -0.0354437 |
| S100A6 | S100 calcium binding protein A6 | -0.0341384 |
| RPL23 | ribosomal protein L23 | -0.0337736 |
| RPL35A | ribosomal protein L35a | -0.0336727 |
| RPLP1 | ribosomal protein, large, P1 | -0.0334984 |
| CSTB | cystatin B (stefin B) | -0.0328145 |
| RPL36 | ribosomal protein L36 | -0.0315329 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0311185 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0301889 |
| B2M | beta-2-microglobulin | -0.0300402 |
| RPS6 | ribosomal protein S6 | -0.0296107 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0278019 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0273771 |
| RPL32 | ribosomal protein L32 | -0.0265224 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0263603 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.026146 |
| HLA-C | major histocompatibility complex, class I, C | -0.0258 |
| RPL31 | ribosomal protein L31 | -0.0256156 |
| STC1 | stanniocalcin 1 | -0.0255439 |
| PTMA | prothymosin, alpha | -0.0253246 |
| EGR1 | early growth response 1 | -0.0250045 |
| TXNIP | thioredoxin interacting protein | -0.0247832 |
| RPL12 | ribosomal protein L12 | -0.0243728 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0243329 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0233232 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0232294 |
| RPS21 | ribosomal protein S21 | -0.0232074 |
| RPL26 | ribosomal protein L26 | -0.022783 |
| RPL35 | ribosomal protein L35 | -0.0224139 |
| RPS14 | ribosomal protein S14 | -0.022021 |
| RPS15 | ribosomal protein S15 | -0.0219783 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0216888 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0214838 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0214125 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0212589 |
| RPS23 | ribosomal protein S23 | -0.0212032 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0207535 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0206924 |
| SEPTIN7 | septin 7 | -0.0206537 |
| RPL37A | ribosomal protein L37a | -0.0200888 |
| RPL9 | ribosomal protein L9 | -0.0199031 |
| RPS8 | ribosomal protein S8 | -0.0195382 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0192418 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0192337 |
| PFN1 | profilin 1 | -0.0191573 |
| RPS13 | ribosomal protein S13 | -0.0190429 |
| RPL28 | ribosomal protein L28 | -0.0188717 |
| S100A9 | S100 calcium binding protein A9 | -0.0187454 |
| COL1A2 | collagen, type I, alpha 2 | -0.0187212 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0184377 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0182739 |
| COL3A1 | collagen, type III, alpha 1 | -0.0182254 |
| GNAS | GNAS complex locus | -0.0176899 |
| RPL34 | ribosomal protein L34 | -0.0176803 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0176263 |
| BSG | basigin (Ok blood group) | -0.0175615 |
| RPS27 | ribosomal protein S27 | -0.0173388 |
| SEC61G | Sec61 gamma subunit | -0.0173331 |
| RPLP0 | ribosomal protein, large, P0 | -0.0173111 |
| S100A4 | S100 calcium binding protein A4 | -0.0172104 |
| RPL27 | ribosomal protein L27 | -0.0171402 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0167715 |
| MYADM | myeloid-associated differentiation marker | -0.0166962 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0165235 |
| RPS11 | ribosomal protein S11 | -0.0163871 |
| RRBP1 | ribosome binding protein 1 | -0.0162457 |
| RPS12 | ribosomal protein S12 | -0.0161306 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0160992 |
| CAVIN1 | caveolae associated protein 1 | -0.0157578 |
| RPS3 | ribosomal protein S3 | -0.0157185 |
| CD81 | CD81 molecule | -0.0156671 |
| RPS29 | ribosomal protein S29 | -0.0156099 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.0154369 |
| FAM162A | family with sequence similarity 162, member A | -0.0153937 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0152765 |
| RPS27A | ribosomal protein S27a | -0.0151664 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0150826 |
| RTN4 | reticulon 4 | -0.0146505 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0145621 |
| DEPP1 | DEPP autophagy regulator 1 | -0.014407 |
