| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0673612 |
| MTSS1 | metastasis suppressor 1 | 0.0640739 |
| PLEC | plectin | 0.0540559 |
| FLNB | filamin B, beta | 0.0539467 |
| SMAD3 | SMAD family member 3 | 0.0525233 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0498519 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0438084 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0424811 |
| FOXO1 | forkhead box O1 | 0.0404806 |
| KIAA1217 | KIAA1217 | 0.0404016 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0382227 |
| PRELID2 | PRELI domain containing 2 | 0.0379994 |
| MYOF | myoferlin | 0.0356014 |
| MSN | moesin | 0.0339189 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0336219 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0301475 |
| AOPEP | aminopeptidase O (putative) | 0.0295265 |
| NEK7 | NIMA-related kinase 7 | 0.0285445 |
| NAV2 | neuron navigator 2 | 0.0284439 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0279766 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0279656 |
| BCL2L1 | BCL2-like 1 | 0.0263567 |
| RAI14 | retinoic acid induced 14 | 0.0259151 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0257834 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0251477 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0243143 |
| BLCAP | bladder cancer associated protein | 0.023669 |
| AHNAK | AHNAK nucleoprotein | 0.0235728 |
| OSMR | oncostatin M receptor | 0.023367 |
| RIN2 | Ras and Rab interactor 2 | 0.0230001 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0229416 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0227354 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0223434 |
| LAMA5 | laminin, alpha 5 | 0.0223203 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.021646 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0215074 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0214369 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0213867 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.021041 |
| ANO6 | anoctamin 6 | 0.0206437 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0206417 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0205751 |
| FNIP1 | folliculin interacting protein 1 | 0.0202946 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0197074 |
| MEF2A | myocyte enhancer factor 2A | 0.0196114 |
| FLNA | filamin A, alpha | 0.0195803 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0194262 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0194234 |
| METTL15 | methyltransferase like 15 | 0.0192065 |
| DIDO1 | death inducer-obliterator 1 | 0.0191621 |
| SULF1 | sulfatase 1 | 0.0191007 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0190472 |
| PTK2 | protein tyrosine kinase 2 | 0.018743 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0186857 |
| EFNA5 | ephrin-A5 | 0.0183719 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0183706 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0182051 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0181964 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0178622 |
| TPM3 | tropomyosin 3 | 0.0175424 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0173386 |
| OGA | O-GlcNAcase | 0.0173231 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0172663 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0169743 |
| TGM2 | transglutaminase 2 | 0.0169184 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0167954 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0167212 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0164332 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0164328 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0163713 |
| LUZP1 | leucine zipper protein 1 | 0.0161935 |
| RBM39 | RNA binding motif protein 39 | 0.0161477 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0160286 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0158833 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0158373 |
| SEPTIN9 | septin 9 | 0.0157838 |
| CLIC4 | chloride intracellular channel 4 | 0.0156606 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0156449 |
| JAG1 | jagged 1 | 0.0155501 |
| SBF2 | SET binding factor 2 | 0.0155322 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0154359 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0153835 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0151975 |
| ANXA11 | annexin A11 | 0.0151497 |
| CUL4B | cullin 4B | 0.0149792 |
| DST | dystonin | 0.0149587 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0149298 |
| ATXN1 | ataxin 1 | 0.0148118 |
| FN1 | fibronectin 1 | 0.0147892 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0146648 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0146509 |
| SMYD3 | SET and MYND domain containing 3 | 0.0144666 |
| RASAL2 | RAS protein activator like 2 | 0.0144188 |
| KIF16B | kinesin family member 16B | 0.0143571 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0143006 |
| IL6ST | interleukin 6 signal transducer | 0.014171 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0141203 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0141149 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.014101 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0140791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.210236 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.149553 |
| TMSB10 | thymosin beta 10 | -0.149416 |
| MT2A | metallothionein 2A | -0.133249 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.120191 |
| PTMA | prothymosin, alpha | -0.117483 |
| RPS6 | ribosomal protein S6 | -0.110129 |
| RPS21 | ribosomal protein S21 | -0.109293 |
| RPLP2 | ribosomal protein, large, P2 | -0.107256 |
| RPS8 | ribosomal protein S8 | -0.0969962 |
| B2M | beta-2-microglobulin | -0.0954949 |
| RPS3 | ribosomal protein S3 | -0.093137 |
| S100A10 | S100 calcium binding protein A10 | -0.0892863 |
| RPS13 | ribosomal protein S13 | -0.0836953 |
| RPS19 | ribosomal protein S19 | -0.083453 |
| RPL11 | ribosomal protein L11 | -0.0807959 |
| RPLP1 | ribosomal protein, large, P1 | -0.0768035 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0753274 |
| ENO1 | enolase 1, (alpha) | -0.0706806 |
| RPS12 | ribosomal protein S12 | -0.0694477 |
| CLU | clusterin | -0.0686667 |
| RPL12 | ribosomal protein L12 | -0.0676787 |
| RPS25 | ribosomal protein S25 | -0.0661965 |
| RPL37A | ribosomal protein L37a | -0.0633851 |
| FTL | ferritin, light polypeptide | -0.0626413 |
| RPL37 | ribosomal protein L37 | -0.0616498 |
| HLA-B | major histocompatibility complex, class I, B | -0.0606822 |
| S100A9 | S100 calcium binding protein A9 | -0.0595815 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0577825 |
| LDHA | lactate dehydrogenase A | -0.0576538 |
| S100A6 | S100 calcium binding protein A6 | -0.0573286 |
| RPS24 | ribosomal protein S24 | -0.0571809 |
| RPL8 | ribosomal protein L8 | -0.0571369 |
| S100A2 | S100 calcium binding protein A2 | -0.0567926 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0567004 |
| RPS23 | ribosomal protein S23 | -0.056215 |
| RPL31 | ribosomal protein L31 | -0.0560124 |
| RPL23 | ribosomal protein L23 | -0.0552742 |
| NDRG1 | N-myc downstream regulated 1 | -0.0532434 |
| RPL7A | ribosomal protein L7a | -0.0529829 |
| RPL19 | ribosomal protein L19 | -0.0524727 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0503645 |
| S100A11 | S100 calcium binding protein A11 | -0.0502151 |
| GNAS | GNAS complex locus | -0.0496643 |
| RPS29 | ribosomal protein S29 | -0.0491944 |
| RPL26 | ribosomal protein L26 | -0.0490662 |
| RPS27A | ribosomal protein S27a | -0.0490419 |
| RPL36 | ribosomal protein L36 | -0.0486499 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0484187 |
| RPL32 | ribosomal protein L32 | -0.0482384 |
| RPL34 | ribosomal protein L34 | -0.0478745 |
| RPS14 | ribosomal protein S14 | -0.0477424 |
| LMNA | lamin A/C | -0.047457 |
| RPS27 | ribosomal protein S27 | -0.0468772 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0451472 |
| RPL35A | ribosomal protein L35a | -0.0450412 |
| RPL36A | ribosomal protein L36a | -0.0441209 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.043685 |
| RPL35 | ribosomal protein L35 | -0.0434053 |
| KRT17 | keratin 17, type I | -0.0425741 |
| RPS16 | ribosomal protein S16 | -0.0421386 |
| TMSB4X | thymosin beta 4, X-linked | -0.0419316 |
| PGK1 | phosphoglycerate kinase 1 | -0.0419123 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0418582 |
| MT1X | metallothionein 1X | -0.0416712 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0415801 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0412135 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0411064 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0410759 |
| RPLP0 | ribosomal protein, large, P0 | -0.0406053 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0399314 |
| RPL28 | ribosomal protein L28 | -0.0396597 |
| RPL27A | ribosomal protein L27a | -0.0395452 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0391996 |
| RPL5 | ribosomal protein L5 | -0.0390098 |
| PFN1 | profilin 1 | -0.0388238 |
| RACK1 | receptor for activated C kinase 1 | -0.0382648 |
| RPS11 | ribosomal protein S11 | -0.0377757 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0376753 |
| STC1 | stanniocalcin 1 | -0.0371049 |
| RPL9 | ribosomal protein L9 | -0.0368019 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0365669 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0361583 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0358404 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0352541 |
| RPL30 | ribosomal protein L30 | -0.0343594 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0343252 |
| RPS17 | ribosomal protein S17 | -0.0337984 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0332642 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0329528 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0327213 |
| RPS5 | ribosomal protein S5 | -0.0326029 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0324489 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.032036 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.03199 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0310057 |
| CALR | calreticulin | -0.0307389 |
| CSTB | cystatin B (stefin B) | -0.0307164 |
| GUK1 | guanylate kinase 1 | -0.0300956 |
| RPL18 | ribosomal protein L18 | -0.0298793 |
