| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.152847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.117531 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.105448 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.096514 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0952446 |
| ACTG1 | actin gamma 1 | 0.0841576 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0841131 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0710233 |
| CALR | calreticulin | 0.0685491 |
| TPM3 | tropomyosin 3 | 0.0674908 |
| DENND4A | DENN/MADD domain containing 4A | 0.0598615 |
| COPA | coatomer protein complex, subunit alpha | 0.0587456 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0573435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0560209 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0554433 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0543628 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.054288 |
| IGF2 | insulin-like growth factor 2 | 0.0536912 |
| APP | amyloid beta (A4) precursor protein | 0.0524918 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0521655 |
| BRD2 | bromodomain containing 2 | 0.0520194 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0517063 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0514027 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0509956 |
| B2M | beta-2-microglobulin | 0.0502551 |
| WDR43 | WD repeat domain 43 | 0.0496322 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0488177 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0466055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.046372 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0463072 |
| USP36 | ubiquitin specific peptidase 36 | 0.0447604 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0445355 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0444192 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0434281 |
| MSN | moesin | 0.0434106 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0433322 |
| RPS12 | ribosomal protein S12 | 0.0432121 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0421026 |
| GLG1 | golgi glycoprotein 1 | 0.0408897 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0406371 |
| MYOF | myoferlin | 0.0405724 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398515 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0397705 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0396217 |
| TFG | TRK-fused gene | 0.039373 |
| ZNF207 | zinc finger protein 207 | 0.0392244 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0390901 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0388616 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0381794 |
| HLA-B | major histocompatibility complex, class I, B | 0.0376653 |
| UBC | ubiquitin C | 0.0369764 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.036965 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0369438 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0367023 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0366596 |
| FAM168A | family with sequence similarity 168, member A | 0.0366538 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.036237 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0360552 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0354543 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0352191 |
| MTMR3 | myotubularin related protein 3 | 0.0349238 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0341186 |
| CMIP | c-Maf inducing protein | 0.0339794 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0336375 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0334936 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0331043 |
| NDRG1 | N-myc downstream regulated 1 | 0.0327638 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.032743 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0327378 |
| TPD52 | tumor protein D52 | 0.0326754 |
| FGB | fibrinogen beta chain | 0.0326035 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0324952 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.032212 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0321066 |
| PUM1 | pumilio RNA-binding family member 1 | 0.031585 |
| JAK1 | Janus kinase 1 | 0.0312742 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0311223 |
| RBM25 | RNA binding motif protein 25 | 0.0310553 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0307343 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0303342 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0297656 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295735 |
| CCNL1 | cyclin L1 | 0.0294678 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292394 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0292165 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0291554 |
| KLC1 | kinesin light chain 1 | 0.0290757 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0290389 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0290089 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0287198 |
| FMNL2 | formin-like 2 | 0.028523 |
| SFTPA2 | surfactant protein A2 | 0.0284206 |
| PCBP2 | poly(rC) binding protein 2 | 0.0284167 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0282695 |
| SPAG9 | sperm associated antigen 9 | 0.0281296 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0280462 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278313 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0277721 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0276847 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0273095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.237753 |
| TMSB10 | thymosin beta 10 | -0.11219 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.062574 |
| GRAMD1B | GRAM domain containing 1B | -0.0596926 |
| BICC1 | BicC family RNA binding protein 1 | -0.0590118 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0580076 |
| WWOX | WW domain containing oxidoreductase | -0.0463415 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0438374 |
| TXNRD1 | thioredoxin reductase 1 | -0.0418477 |
| FTL | ferritin, light polypeptide | -0.038052 |
| RPS21 | ribosomal protein S21 | -0.0354838 |
| RPL18 | ribosomal protein L18 | -0.0338682 |
| NNMT | nicotinamide N-methyltransferase | -0.0322451 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0321214 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0303438 |
| RPS19 | ribosomal protein S19 | -0.0297198 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0291571 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0281456 |
| FOXP1 | forkhead box P1 | -0.0261618 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0255136 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0251739 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0248981 |
| SERF2 | small EDRK-rich factor 2 | -0.024639 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0239422 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0222452 |
| RPS27A | ribosomal protein S27a | -0.0222253 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0222234 |
| RPS24 | ribosomal protein S24 | -0.0219307 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0218214 |
| TUBA1B | tubulin, alpha 1b | -0.0217849 |
| EPGN | epithelial mitogen | -0.0214488 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0213294 |
| RPS23 | ribosomal protein S23 | -0.0213171 |
| S100A11 | S100 calcium binding protein A11 | -0.0212972 |
| FGG | fibrinogen gamma chain | -0.0210142 |
| RPL23 | ribosomal protein L23 | -0.0209273 |
| GLIS3 | GLIS family zinc finger 3 | -0.0205364 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0204052 |
| IER3 | immediate early response 3 | -0.0200018 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0199149 |
| PRKD1 | protein kinase D1 | -0.0196002 |
| GTDC1 | glycosyltransferase-like domain containing 1 | -0.0195806 |
| ECT2 | epithelial cell transforming 2 | -0.019387 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0190408 |
| ATM | ATM serine/threonine kinase | -0.0190103 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0189088 |
| RPL9 | ribosomal protein L9 | -0.0188319 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0183774 |
| RPL30 | ribosomal protein L30 | -0.0182114 |
| AHR | aryl hydrocarbon receptor | -0.0181474 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0180666 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0173565 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0173466 |
| RNF217 | ring finger protein 217 | -0.0171768 |
| RPL36A | ribosomal protein L36a | -0.0170692 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0170665 |
| GPC6 | glypican 6 | -0.0168803 |
| NEGR1 | neuronal growth regulator 1 | -0.016839 |
| TUBB | tubulin, beta class I | -0.0167594 |
| NAV3 | neuron navigator 3 | -0.0165244 |
| ZNF804A | zinc finger protein 804A | -0.0164455 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0162699 |
| ROMO1 | reactive oxygen species modulator 1 | -0.0162124 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0161032 |
| PCED1B | PC-esterase domain containing 1B | -0.0160308 |
| RPL8 | ribosomal protein L8 | -0.0156418 |
| RSPRY1 | ring finger and SPRY domain containing 1 | -0.0153179 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0152875 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0152524 |
| SHTN1 | shootin 1 | -0.0151237 |
| FHIT | fragile histidine triad | -0.0149336 |
| JMJD1C | jumonji domain containing 1C | -0.0148602 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0146777 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0146705 |
| NABP1 | nucleic acid binding protein 1 | -0.0146222 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | -0.0145117 |
| CENPF | centromere protein F, 350/400kDa | -0.0143999 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0143832 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.01438 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0143455 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0142571 |
| RPS29 | ribosomal protein S29 | -0.0142342 |
| RPLP2 | ribosomal protein, large, P2 | -0.0142163 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0142128 |
| ANLN | anillin, actin binding protein | -0.0140623 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0140248 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0139814 |
| RPL36AL | ribosomal protein L36a-like | -0.0139741 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0139724 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0139717 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0139637 |
| WDR70 | WD repeat domain 70 | -0.013901 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0138185 |
| NFIA | nuclear factor I/A | -0.0134549 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0133883 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0133577 |
| RPS3 | ribosomal protein S3 | -0.0132503 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0131989 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.013166 |
| FRYL | FRY-like | -0.0130571 |
