| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Eplerenone_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 0.162157 |
| POTEF | POTE ankyrin domain family, member F | 0.146559 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.139476 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0985465 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.098431 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0811519 |
| FN1 | fibronectin 1 | 0.0798454 |
| KRT8 | keratin 8, type II | 0.06535 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0595148 |
| CD109 | CD109 molecule | 0.0585411 |
| EXT1 | exostosin glycosyltransferase 1 | 0.057884 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.052947 |
| PLAU | plasminogen activator, urokinase | 0.0507868 |
| CANX | calnexin | 0.0502614 |
| VCL | vinculin | 0.0481562 |
| CALR | calreticulin | 0.0468025 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.044521 |
| MSI2 | musashi RNA-binding protein 2 | 0.0440935 |
| PTK2 | protein tyrosine kinase 2 | 0.0435438 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.043262 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.04257 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0422263 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0421116 |
| AHNAK | AHNAK nucleoprotein | 0.0418346 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0412225 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0412064 |
| INTS6 | integrator complex subunit 6 | 0.0408856 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0404524 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0404225 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0403944 |
| COPA | coatomer protein complex, subunit alpha | 0.0397575 |
| VEGFA | vascular endothelial growth factor A | 0.0395474 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0384183 |
| RNF213 | ring finger protein 213 | 0.0383175 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0375449 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.037422 |
| FLNB | filamin B, beta | 0.0367642 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0359569 |
| CTBP2 | C-terminal binding protein 2 | 0.0355462 |
| PLEC | plectin | 0.0347562 |
| FNIP1 | folliculin interacting protein 1 | 0.0339477 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0335902 |
| EFNA5 | ephrin-A5 | 0.0333413 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0332742 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0323725 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0320163 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.031747 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0317214 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0315182 |
| ARF4 | ADP-ribosylation factor 4 | 0.0314085 |
| MYOF | myoferlin | 0.0312382 |
| MCU | mitochondrial calcium uniporter | 0.0309694 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0301775 |
| SEPTIN11 | septin 11 | 0.0300298 |
| RIGI | RNA sensor RIG-I | 0.0298775 |
| RCOR1 | REST corepressor 1 | 0.0298212 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0296211 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0296093 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0293505 |
| ARF1 | ADP-ribosylation factor 1 | 0.0289938 |
| KRT7 | keratin 7, type II | 0.0288392 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0287372 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0279981 |
| FAM13A | family with sequence similarity 13, member A | 0.0278955 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0278002 |
| PALLD | palladin, cytoskeletal associated protein | 0.0277861 |
| MX1 | MX dynamin-like GTPase 1 | 0.0277772 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0274908 |
| CERT1 | ceramide transporter 1 | 0.0274189 |
| MYO1E | myosin IE | 0.0271499 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0265918 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0263997 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0263011 |
| FLNC | filamin C, gamma | 0.0261158 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0259346 |
| CLIC4 | chloride intracellular channel 4 | 0.0258784 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0253421 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.025201 |
| IRF6 | interferon regulatory factor 6 | 0.0251969 |
| FBXO34 | F-box protein 34 | 0.0251397 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.025062 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.025033 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0249158 |
| NAV2 | neuron navigator 2 | 0.0248401 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0247482 |
| HDLBP | high density lipoprotein binding protein | 0.0247434 |
| UBAP1 | ubiquitin associated protein 1 | 0.0245765 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0243657 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0243383 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0243041 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0240377 |
| QKI | QKI, KH domain containing, RNA binding | 0.0236911 |
| TUFT1 | tuftelin 1 | 0.0235486 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0234457 |
| CCND1 | cyclin D1 | 0.0234017 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0233222 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0231314 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0228535 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0227603 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0227007 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229633 |
| NDRG1 | N-myc downstream regulated 1 | -0.183434 |
| FTL | ferritin, light polypeptide | -0.139323 |
| TMSB10 | thymosin beta 10 | -0.127249 |
| PTMA | prothymosin, alpha | -0.116487 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.114459 |
| MT2A | metallothionein 2A | -0.109271 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0960526 |
| RPLP2 | ribosomal protein, large, P2 | -0.0846432 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0843835 |
| GOLGA4 | golgin A4 | -0.0783271 |
| RPS6 | ribosomal protein S6 | -0.0765552 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0763321 |
| RPS3 | ribosomal protein S3 | -0.0715539 |
| S100A6 | S100 calcium binding protein A6 | -0.068454 |
| RPS19 | ribosomal protein S19 | -0.0671015 |
| RPS23 | ribosomal protein S23 | -0.0667967 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0667798 |
| RPL37A | ribosomal protein L37a | -0.0658244 |
| RPLP1 | ribosomal protein, large, P1 | -0.0653141 |
| RPL8 | ribosomal protein L8 | -0.0650298 |
| HMGB2 | high mobility group box 2 | -0.0646966 |
| RPS2 | ribosomal protein S2 | -0.0632475 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0613844 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0609543 |
| SDC4 | syndecan 4 | -0.0601987 |
| RPS12 | ribosomal protein S12 | -0.058919 |
| RPS29 | ribosomal protein S29 | -0.0582574 |
| TXNRD1 | thioredoxin reductase 1 | -0.057923 |
| RPS8 | ribosomal protein S8 | -0.055238 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0542114 |
| RPL32 | ribosomal protein L32 | -0.0534507 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0532374 |
| RPL9 | ribosomal protein L9 | -0.0531949 |
| RPS13 | ribosomal protein S13 | -0.0530555 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0524315 |
| RPL12 | ribosomal protein L12 | -0.0515089 |
| RBM25 | RNA binding motif protein 25 | -0.0509027 |
| RPL19 | ribosomal protein L19 | -0.0499272 |
| HMGA1 | high mobility group AT-hook 1 | -0.0490586 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.047466 |
| RPL5 | ribosomal protein L5 | -0.0465572 |
| RPL11 | ribosomal protein L11 | -0.0463328 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0455933 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0448796 |
| RPL26 | ribosomal protein L26 | -0.0433806 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0421205 |
| RPL7 | ribosomal protein L7 | -0.0419209 |
| RPL38 | ribosomal protein L38 | -0.0415741 |
| RPS17 | ribosomal protein S17 | -0.0407067 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0404355 |
| RPL15 | ribosomal protein L15 | -0.0400678 |
| MKI67 | marker of proliferation Ki-67 | -0.0399823 |
| RPL34 | ribosomal protein L34 | -0.0399462 |
| GPX4 | glutathione peroxidase 4 | -0.0396562 |
| S100A10 | S100 calcium binding protein A10 | -0.0394131 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0386715 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0383235 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0382479 |
| RPS27A | ribosomal protein S27a | -0.0381629 |
| RPL28 | ribosomal protein L28 | -0.0367106 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0365963 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0363834 |
| RPS14 | ribosomal protein S14 | -0.0359402 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0358035 |
| G0S2 | G0/G1 switch 2 | -0.0349944 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0349387 |
| RPL30 | ribosomal protein L30 | -0.0348639 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0347275 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0343292 |
| RPS16 | ribosomal protein S16 | -0.0342999 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0341591 |
| RACK1 | receptor for activated C kinase 1 | -0.0339036 |
| RPS21 | ribosomal protein S21 | -0.0337891 |
| RPL36 | ribosomal protein L36 | -0.0336246 |
| RPL36A | ribosomal protein L36a | -0.0330371 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0330084 |
| RPS27 | ribosomal protein S27 | -0.0328634 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0328453 |
| RPS11 | ribosomal protein S11 | -0.032747 |
| SEPTIN7 | septin 7 | -0.0326229 |
| ASPH | aspartate beta-hydroxylase | -0.0325378 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.032368 |
| SET | SET nuclear proto-oncogene | -0.031908 |
| RNF145 | ring finger protein 145 | -0.0318275 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0317731 |
| GOLT1B | golgi transport 1B | -0.031159 |
| RPL37 | ribosomal protein L37 | -0.0310616 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0309859 |
| RPL31 | ribosomal protein L31 | -0.0308595 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0307942 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0306127 |
| FAM3C | family with sequence similarity 3, member C | -0.0304635 |
| RPL18 | ribosomal protein L18 | -0.0303064 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0298964 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0295494 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.029391 |
| RPL23 | ribosomal protein L23 | -0.0293856 |
| MYO10 | myosin X | -0.0292796 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0291686 |
