| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.130734 |
| VCL | vinculin | 0.106731 |
| AHNAK | AHNAK nucleoprotein | 0.100916 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0949169 |
| PKM | pyruvate kinase, muscle | 0.088399 |
| EGFR | epidermal growth factor receptor | 0.0877336 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0869214 |
| EZR | ezrin | 0.0856352 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0831263 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0806058 |
| NBEA | neurobeachin | 0.079703 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0702931 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0688299 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0686696 |
| PYGB | phosphorylase, glycogen; brain | 0.0664275 |
| POTEF | POTE ankyrin domain family, member F | 0.0660215 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.065532 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.064248 |
| TJP1 | tight junction protein 1 | 0.0632944 |
| EFNA5 | ephrin-A5 | 0.0628536 |
| HDAC9 | histone deacetylase 9 | 0.062593 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.061402 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0558866 |
| TXNRD1 | thioredoxin reductase 1 | 0.0549754 |
| FLNB | filamin B, beta | 0.0544295 |
| SLC38A2 | solute carrier family 38, member 2 | 0.052992 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0472074 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0452277 |
| FOXP1 | forkhead box P1 | 0.0448489 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0443683 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0442313 |
| SMYD3 | SET and MYND domain containing 3 | 0.0437511 |
| RTN4 | reticulon 4 | 0.0430077 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0426031 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0420658 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0416119 |
| GLI2 | GLI family zinc finger 2 | 0.0415843 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0409627 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.040108 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0400966 |
| PDGFC | platelet derived growth factor C | 0.0388287 |
| JMJD1C | jumonji domain containing 1C | 0.0386605 |
| PTMA | prothymosin, alpha | 0.0384711 |
| MKI67 | marker of proliferation Ki-67 | 0.0383495 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0377817 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0377727 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0377021 |
| EVI5 | ecotropic viral integration site 5 | 0.0374561 |
| RHOA | ras homolog family member A | 0.037267 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0367945 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0362491 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0358439 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0351845 |
| CCND1 | cyclin D1 | 0.0346652 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0344588 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0339595 |
| PGK1 | phosphoglycerate kinase 1 | 0.0333724 |
| ANXA1 | annexin A1 | 0.0328722 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.032817 |
| TMF1 | TATA element modulatory factor 1 | 0.0326779 |
| ACTG1 | actin gamma 1 | 0.0323195 |
| TMEM65 | transmembrane protein 65 | 0.0322677 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0322201 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0320601 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0319937 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0319582 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0318072 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0317617 |
| BMP2K | BMP2 inducible kinase | 0.0316073 |
| OSMR | oncostatin M receptor | 0.0313899 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0303662 |
| DUSP4 | dual specificity phosphatase 4 | 0.0303457 |
| NFIA | nuclear factor I/A | 0.0303063 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0299336 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0297407 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0297065 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.029684 |
| MYO5C | myosin VC | 0.0295565 |
| NCKAP1 | NCK-associated protein 1 | 0.0290436 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0289799 |
| PARD3 | par-3 family cell polarity regulator | 0.0289342 |
| TPM4 | tropomyosin 4 | 0.0288525 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0287831 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0284953 |
| LOXL3 | lysyl oxidase-like 3 | 0.0283479 |
| ZNF148 | zinc finger protein 148 | 0.0283369 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0283142 |
| AMOTL2 | angiomotin like 2 | 0.028135 |
| DIAPH2 | diaphanous-related formin 2 | 0.0278362 |
| ATP9B | ATPase, class II, type 9B | 0.0276623 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0274364 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0274292 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0274152 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0273984 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0273536 |
| DSTN | destrin (actin depolymerizing factor) | 0.026738 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0267188 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0262133 |
| LDHA | lactate dehydrogenase A | 0.0259086 |
| KIF5B | kinesin family member 5B | 0.0256301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS23 | ribosomal protein S23 | -0.0448537 |
| RPS6 | ribosomal protein S6 | -0.0447199 |
| RPLP2 | ribosomal protein, large, P2 | -0.0440639 |
| RPL31 | ribosomal protein L31 | -0.0415481 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.03931 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0355381 |
| RPL36 | ribosomal protein L36 | -0.0348882 |
| RPL23 | ribosomal protein L23 | -0.034807 |
| RPL26 | ribosomal protein L26 | -0.0342812 |
| FTL | ferritin, light polypeptide | -0.0338325 |
| MT2A | metallothionein 2A | -0.0323315 |
| RPL9 | ribosomal protein L9 | -0.0304832 |
| RPS19 | ribosomal protein S19 | -0.0302784 |
| RPS3 | ribosomal protein S3 | -0.0302369 |
| RPS25 | ribosomal protein S25 | -0.0298265 |
| RPLP1 | ribosomal protein, large, P1 | -0.0275969 |
| RPL32 | ribosomal protein L32 | -0.0269783 |
| RPS8 | ribosomal protein S8 | -0.0266841 |
| TMSB10 | thymosin beta 10 | -0.0266287 |
| RPS13 | ribosomal protein S13 | -0.026238 |
| RPL34 | ribosomal protein L34 | -0.0255194 |
| RPL37A | ribosomal protein L37a | -0.0248316 |
| RPS12 | ribosomal protein S12 | -0.0235667 |
| RPL35A | ribosomal protein L35a | -0.0229403 |
| RPS29 | ribosomal protein S29 | -0.0228062 |
| PFN1 | profilin 1 | -0.0226642 |
| RPLP0 | ribosomal protein, large, P0 | -0.022108 |
| S100A9 | S100 calcium binding protein A9 | -0.0218071 |
| RPS14 | ribosomal protein S14 | -0.021365 |
| RPL11 | ribosomal protein L11 | -0.0213412 |
| RPL13A | ribosomal protein L13a | -0.0213234 |
| RPS17 | ribosomal protein S17 | -0.0206508 |
| RPL27 | ribosomal protein L27 | -0.0204122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0192122 |
| RPS5 | ribosomal protein S5 | -0.018654 |
| RPL7A | ribosomal protein L7a | -0.0183267 |
| RPL5 | ribosomal protein L5 | -0.0177511 |
| RPS10 | ribosomal protein S10 | -0.0175494 |
| RPL35 | ribosomal protein L35 | -0.0174681 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0164894 |
| RPL18 | ribosomal protein L18 | -0.016298 |
| RPS16 | ribosomal protein S16 | -0.0161882 |
| RPS24 | ribosomal protein S24 | -0.0156791 |
| FAM162A | family with sequence similarity 162, member A | -0.0154351 |
| RPL12 | ribosomal protein L12 | -0.0153629 |
| RPS27 | ribosomal protein S27 | -0.0151675 |
| RRBP1 | ribosome binding protein 1 | -0.0151509 |
| RPL38 | ribosomal protein L38 | -0.014696 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0146199 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0144615 |
| RPL28 | ribosomal protein L28 | -0.0133535 |
| RPS11 | ribosomal protein S11 | -0.0127316 |
| SEC61G | Sec61 gamma subunit | -0.0126489 |
| RPS27A | ribosomal protein S27a | -0.0125895 |
| RPL8 | ribosomal protein L8 | -0.0123197 |
| RPS21 | ribosomal protein S21 | -0.012254 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0122081 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0113527 |
| RPS27L | ribosomal protein S27-like | -0.0102627 |
| MFSD4B | major facilitator superfamily domain containing 4B | -0.0102177 |
| MT1X | metallothionein 1X | -0.0101921 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -0.0101226 |
| VIM | vimentin | -0.00988974 |
| APLF | aprataxin and PNKP like factor | -0.00983943 |
| PRDX2 | peroxiredoxin 2 | -0.00977751 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0097731 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | -0.00972012 |
| ASTN2 | astrotactin 2 | -0.00956638 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.00937402 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.00936049 |
| RPL19 | ribosomal protein L19 | -0.0093256 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.00924052 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00917191 |
| RPL37 | ribosomal protein L37 | -0.00906165 |
| ATP5MC2 | ATP synthase membrane subunit c locus 2 | -0.00902746 |
| S100A6 | S100 calcium binding protein A6 | -0.00890311 |
| RRAGD | Ras-related GTP binding D | -0.00888129 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00878667 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.00877927 |
| MED13L | mediator complex subunit 13-like | -0.00866642 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00861358 |
| ABHD3 | abhydrolase domain containing 3 | -0.0085686 |
| USP15 | ubiquitin specific peptidase 15 | -0.00848646 |
| ROMO1 | reactive oxygen species modulator 1 | -0.00841247 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0083674 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00831783 |
| PURA | purine-rich element binding protein A | -0.00831543 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00831407 |
| COX19 | COX19 cytochrome c oxidase assembly factor | -0.00825446 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00818779 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.00817184 |
| SRP19 | signal recognition particle 19kDa | -0.00810562 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00809901 |
| AGR2 | anterior gradient 2 | -0.00807561 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0079974 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0079671 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00794588 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.00791245 |
| RPL36A | ribosomal protein L36a | -0.00787033 |
| TMEM258 | transmembrane protein 258 | -0.00786704 |
