| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.108171 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0695439 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0694365 |
| POTEF | POTE ankyrin domain family, member F | 0.0671421 |
| MSN | moesin | 0.0590867 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.056827 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0557472 |
| EGFR | epidermal growth factor receptor | 0.0519213 |
| SPAG9 | sperm associated antigen 9 | 0.051647 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0477968 |
| NRXN3 | neurexin 3 | 0.047065 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0458532 |
| COL5A1 | collagen, type V, alpha 1 | 0.045753 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0444044 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0436368 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0434849 |
| NAV2 | neuron navigator 2 | 0.043103 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.041748 |
| VEGFA | vascular endothelial growth factor A | 0.0413135 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0409454 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0388652 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0374358 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.037422 |
| PTK2 | protein tyrosine kinase 2 | 0.0358138 |
| KAZN | kazrin, periplakin interacting protein | 0.0329088 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0321093 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0316346 |
| ZNF148 | zinc finger protein 148 | 0.0312111 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0306363 |
| TNS3 | tensin 3 | 0.030478 |
| JAK1 | Janus kinase 1 | 0.0301319 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0297706 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0296057 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0291392 |
| VEGFC | vascular endothelial growth factor C | 0.0287747 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0283642 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0281427 |
| NDRG1 | N-myc downstream regulated 1 | 0.0279989 |
| CUL3 | cullin 3 | 0.0272122 |
| FNIP1 | folliculin interacting protein 1 | 0.0271503 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0270385 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268711 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0264296 |
| C1D | C1D nuclear receptor corepressor | 0.0264005 |
| FN1 | fibronectin 1 | 0.0262099 |
| ARRDC3 | arrestin domain containing 3 | 0.0260665 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0257539 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0253152 |
| CCNL1 | cyclin L1 | 0.0251936 |
| PRRC2C | proline-rich coiled-coil 2C | 0.025143 |
| QKI | QKI, KH domain containing, RNA binding | 0.0250564 |
| MYLK | myosin light chain kinase | 0.0242346 |
| RNF145 | ring finger protein 145 | 0.0241737 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0239996 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0237983 |
| CTNNBL1 | catenin, beta like 1 | 0.0232772 |
| AHNAK | AHNAK nucleoprotein | 0.0232265 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0232163 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.023144 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0231131 |
| CLTC | clathrin, heavy chain (Hc) | 0.0229107 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.022756 |
| NOTCH2 | notch 2 | 0.0226595 |
| YEATS2 | YEATS domain containing 2 | 0.0220983 |
| GSE1 | Gse1 coiled-coil protein | 0.0220387 |
| ATP13A3 | ATPase type 13A3 | 0.0219638 |
| NBAS | neuroblastoma amplified sequence | 0.0218377 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.021669 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0215828 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0210995 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.021002 |
| ZNF292 | zinc finger protein 292 | 0.0210003 |
| B2M | beta-2-microglobulin | 0.0209969 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0209692 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0203643 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0202369 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0201313 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0201209 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0200139 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.020002 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0198868 |
| NCKAP1 | NCK-associated protein 1 | 0.0197709 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0197405 |
| MED13L | mediator complex subunit 13-like | 0.0196615 |
| TOP1 | topoisomerase (DNA) I | 0.0196543 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0195571 |
| CADM1 | cell adhesion molecule 1 | 0.0195327 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0194969 |
| ANTXR2 | anthrax toxin receptor 2 | 0.019401 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0193334 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.01924 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0191781 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0191525 |
| DENND5A | DENN/MADD domain containing 5A | 0.0191445 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0191412 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0189695 |
| FBXO11 | F-box protein 11 | 0.0188515 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0187137 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0186738 |
| LIMA1 | LIM domain and actin binding 1 | 0.0186293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.255544 |
| TMSB10 | thymosin beta 10 | -0.189129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.179768 |
| MT2A | metallothionein 2A | -0.171966 |
| VIM | vimentin | -0.133374 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0930103 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0929724 |
| FTL | ferritin, light polypeptide | -0.0787008 |
| HLA-B | major histocompatibility complex, class I, B | -0.0686864 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0664196 |
| STC1 | stanniocalcin 1 | -0.0610476 |
| PTMA | prothymosin, alpha | -0.0592581 |
| PRSS23 | protease, serine, 23 | -0.0511052 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0501916 |
| S100A10 | S100 calcium binding protein A10 | -0.0494478 |
| COL1A2 | collagen, type I, alpha 2 | -0.0489559 |
| RPL34 | ribosomal protein L34 | -0.0477335 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0445421 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0441621 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.042539 |
| LOX | lysyl oxidase | -0.0424177 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0411761 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0392962 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391776 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.038423 |
| SDC4 | syndecan 4 | -0.0381219 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0379597 |
| UBC | ubiquitin C | -0.037702 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0368996 |
| RPLP1 | ribosomal protein, large, P1 | -0.0368568 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.036835 |
| HLA-C | major histocompatibility complex, class I, C | -0.0366597 |
| S100A9 | S100 calcium binding protein A9 | -0.0366493 |
| RPL35A | ribosomal protein L35a | -0.0360837 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0354463 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0353793 |
| COL1A1 | collagen, type I, alpha 1 | -0.0353233 |
| MT1X | metallothionein 1X | -0.034824 |
| ENO1 | enolase 1, (alpha) | -0.0337017 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0331406 |
| ANXA2 | annexin A2 | -0.0329028 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0324532 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0313853 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0311801 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0304433 |
| CCNI | cyclin I | -0.0299565 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0290887 |
| TUBB | tubulin, beta class I | -0.0290591 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0286705 |
| HLA-A | major histocompatibility complex, class I, A | -0.0285905 |
| LOXL2 | lysyl oxidase-like 2 | -0.0285541 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0284997 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0280104 |
| GNAS | GNAS complex locus | -0.0278953 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0277209 |
| MAP1B | microtubule-associated protein 1B | -0.0275606 |
| RPS23 | ribosomal protein S23 | -0.0275212 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274934 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0269549 |
| RPL11 | ribosomal protein L11 | -0.0269228 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0268661 |
| RPL28 | ribosomal protein L28 | -0.0268229 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0265847 |
| NAV1 | neuron navigator 1 | -0.0264105 |
| ARF1 | ADP-ribosylation factor 1 | -0.02613 |
| FUS | FUS RNA binding protein | -0.0259779 |
| MORF4L2 | mortality factor 4 like 2 | -0.025951 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0255842 |
| RPS29 | ribosomal protein S29 | -0.0255686 |
| SQSTM1 | sequestosome 1 | -0.0253124 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0250009 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0248065 |
| RPL31 | ribosomal protein L31 | -0.0246756 |
| RPS14 | ribosomal protein S14 | -0.0245072 |
| RPL12 | ribosomal protein L12 | -0.0242935 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.024096 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0237656 |
| ADM | adrenomedullin | -0.0235627 |
| RPS12 | ribosomal protein S12 | -0.0235625 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0235154 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0233272 |
| CAVIN1 | caveolae associated protein 1 | -0.0230133 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.022922 |
| RPL7A | ribosomal protein L7a | -0.0228501 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0227071 |
| LDHA | lactate dehydrogenase A | -0.0224544 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0221841 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0221321 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.021967 |
| CANX | calnexin | -0.0218747 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0216313 |
| TMEM87A | transmembrane protein 87A | -0.0213549 |
| MYOF | myoferlin | -0.0212795 |
| AK1 | adenylate kinase 1 | -0.0211253 |
| YBX3 | Y box binding protein 3 | -0.0211166 |
| LMAN2 | lectin, mannose-binding 2 | -0.0209358 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0208831 |
| RPL35 | ribosomal protein L35 | -0.0207758 |
| MTPN | myotrophin | -0.020654 |
| RPL36A | ribosomal protein L36a | -0.0205968 |
