| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0591938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0580697 |
| GOLGA4 | golgin A4 | 0.048915 |
| RBM39 | RNA binding motif protein 39 | 0.048485 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0473957 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0440725 |
| ANLN | anillin, actin binding protein | 0.0427819 |
| ZNF292 | zinc finger protein 292 | 0.0424346 |
| KIF5B | kinesin family member 5B | 0.0412069 |
| NAV2 | neuron navigator 2 | 0.0407219 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0397995 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0396323 |
| MATR3 | matrin 3 | 0.0384328 |
| CANX | calnexin | 0.0375914 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.037206 |
| YAP1 | Yes-associated protein 1 | 0.0369436 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0366644 |
| CENPF | centromere protein F, 350/400kDa | 0.0353847 |
| CLTC | clathrin, heavy chain (Hc) | 0.0349754 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0347026 |
| ANKRD28 | ankyrin repeat domain 28 | 0.03446 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0342955 |
| TXNRD1 | thioredoxin reductase 1 | 0.0341614 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0341362 |
| CALU | calumenin | 0.0337954 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0330218 |
| TPX2 | TPX2, microtubule-associated | 0.0328519 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0325713 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0314915 |
| NUP58 | nucleoporin 58 | 0.0314552 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0314497 |
| CEP250 | centrosomal protein 250kDa | 0.0312619 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0292211 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0289945 |
| SPAG9 | sperm associated antigen 9 | 0.0288684 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0282702 |
| DIAPH3 | diaphanous-related formin 3 | 0.0281104 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0281032 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0278684 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0276173 |
| GOLGB1 | golgin B1 | 0.0276044 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0275055 |
| KIAA1958 | KIAA1958 | 0.0273724 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0271021 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0270171 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0268272 |
| XPO1 | exportin 1 | 0.026283 |
| FNIP1 | folliculin interacting protein 1 | 0.0261311 |
| DNER | delta/notch-like EGF repeat containing | 0.0258374 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0256458 |
| SMYD3 | SET and MYND domain containing 3 | 0.0254668 |
| CPNE1 | copine I | 0.0254319 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0253487 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0252549 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0249943 |
| PAPOLA | poly(A) polymerase alpha | 0.024663 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0245994 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0245916 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0243442 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0241536 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0241467 |
| TFG | TRK-fused gene | 0.0240267 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0237561 |
| TMF1 | TATA element modulatory factor 1 | 0.0236292 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0235268 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234997 |
| AHNAK | AHNAK nucleoprotein | 0.023492 |
| GOLGA2 | golgin A2 | 0.0234774 |
| PCBP2 | poly(rC) binding protein 2 | 0.0232595 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0229142 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0228596 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0228518 |
| ETNK1 | ethanolamine kinase 1 | 0.0228141 |
| CUL5 | cullin 5 | 0.0225931 |
| MKI67 | marker of proliferation Ki-67 | 0.0225146 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0224368 |
| QKI | QKI, KH domain containing, RNA binding | 0.0223246 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0222244 |
| HELZ | helicase with zinc finger | 0.0221869 |
| CEP295 | centrosomal protein 295kDa | 0.022139 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0221027 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0220888 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0219069 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0219021 |
| ECT2 | epithelial cell transforming 2 | 0.0217817 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0217544 |
| IL6ST | interleukin 6 signal transducer | 0.0217396 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.021535 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0213586 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.021241 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0206372 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0206356 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0204881 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0204078 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0203801 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.020299 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0201885 |
| DCP2 | decapping mRNA 2 | 0.020182 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0200238 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0199507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.104447 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10287 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0838158 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0621105 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.06013 |
| VIM | vimentin | -0.0581658 |
| ANGPTL4 | angiopoietin-like 4 | -0.0495751 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0464954 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0431104 |
| RIGI | RNA sensor RIG-I | -0.0427823 |
| RAI14 | retinoic acid induced 14 | -0.0427081 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0387264 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0384741 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0378974 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0371575 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.034974 |
| HMGA2 | high mobility group AT-hook 2 | -0.0345057 |
| RPL35A | ribosomal protein L35a | -0.034457 |
| LDHA | lactate dehydrogenase A | -0.0319921 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.031977 |
| EGR1 | early growth response 1 | -0.0315091 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0307382 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0303442 |
| VCL | vinculin | -0.0302551 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0301371 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.029967 |
| RPLP1 | ribosomal protein, large, P1 | -0.029823 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0290406 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0289757 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0288125 |
| HLA-A | major histocompatibility complex, class I, A | -0.0281395 |
| PTMA | prothymosin, alpha | -0.027945 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0278114 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0277439 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0273278 |
| NALCN | sodium leak channel, non selective | -0.0273065 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.02679 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0262577 |
| MT2A | metallothionein 2A | -0.0262273 |
| GPC5 | glypican 5 | -0.026175 |
| BPTF | bromodomain PHD finger transcription factor | -0.0261028 |
| GNAS | GNAS complex locus | -0.0260461 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0260033 |
| RPL36 | ribosomal protein L36 | -0.0259532 |
| ZFHX3 | zinc finger homeobox 3 | -0.0254744 |
| HLA-B | major histocompatibility complex, class I, B | -0.0254665 |
| PRSS23 | protease, serine, 23 | -0.0252315 |
| DST | dystonin | -0.025213 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0250588 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0248813 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0247564 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0246286 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0244092 |
| S100A10 | S100 calcium binding protein A10 | -0.0240517 |
| PRR16 | proline rich 16 | -0.0237348 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0237007 |
| RPS13 | ribosomal protein S13 | -0.0234588 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.023006 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0224758 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0223814 |
| FMN1 | formin 1 | -0.0223413 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0221273 |
| JAK1 | Janus kinase 1 | -0.0220788 |
| ENO1 | enolase 1, (alpha) | -0.0220031 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0219843 |
| IER3 | immediate early response 3 | -0.0219602 |
| PLEK2 | pleckstrin 2 | -0.0218493 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0217372 |
| S100A6 | S100 calcium binding protein A6 | -0.0216369 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0216345 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0216131 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0212976 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.020897 |
| HDAC9 | histone deacetylase 9 | -0.0208892 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0208712 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0208632 |
| PCED1B | PC-esterase domain containing 1B | -0.0207307 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0206744 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0205999 |
| EFNA5 | ephrin-A5 | -0.0204017 |
| H3-3B | H3.3 histone B | -0.0203366 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0201338 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0200773 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0200659 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.020051 |
| RPL19 | ribosomal protein L19 | -0.0200378 |
| EGFR | epidermal growth factor receptor | -0.0199998 |
| PRKCA | protein kinase C, alpha | -0.0199673 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0197914 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.019777 |
| FTL | ferritin, light polypeptide | -0.0196909 |
| S100A9 | S100 calcium binding protein A9 | -0.019595 |
| PODXL | podocalyxin-like | -0.0194089 |
| IFI44 | interferon-induced protein 44 | -0.0193917 |
| GPATCH2L | G patch domain containing 2-like | -0.0188308 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0186906 |
| SVIL | supervillin | -0.0186884 |
| B2M | beta-2-microglobulin | -0.0186444 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0182555 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0182068 |
