| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Eplerenone perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Eplerenone_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.140377 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.122585 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0776277 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0744207 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0717245 |
| B2M | beta-2-microglobulin | 0.0700357 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.069777 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0690751 |
| VEGFA | vascular endothelial growth factor A | 0.0652205 |
| GOLGA4 | golgin A4 | 0.063906 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0568638 |
| TMEM156 | transmembrane protein 156 | 0.0556347 |
| OSMR | oncostatin M receptor | 0.0543434 |
| CALR | calreticulin | 0.0541879 |
| SMOX | spermine oxidase | 0.051534 |
| SUCO | SUN domain containing ossification factor | 0.0504157 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0491846 |
| CENPF | centromere protein F, 350/400kDa | 0.0486704 |
| COPA | coatomer protein complex, subunit alpha | 0.0481822 |
| CANX | calnexin | 0.0481774 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0479603 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0457037 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0452881 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0441386 |
| CD44 | CD44 molecule (Indian blood group) | 0.0440799 |
| TPM3 | tropomyosin 3 | 0.0440551 |
| CAB39 | calcium binding protein 39 | 0.0431468 |
| FNBP1 | formin binding protein 1 | 0.0426334 |
| TXNRD1 | thioredoxin reductase 1 | 0.0423691 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.042268 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0421167 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0420218 |
| ZNF292 | zinc finger protein 292 | 0.0418092 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0416105 |
| SMAD3 | SMAD family member 3 | 0.0413133 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0412629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0399094 |
| TPR | translocated promoter region, nuclear basket protein | 0.0394056 |
| HELZ | helicase with zinc finger | 0.0388184 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0381071 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0381007 |
| CALU | calumenin | 0.0379325 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0378437 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0376212 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0371055 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0361294 |
| RNF145 | ring finger protein 145 | 0.0359503 |
| PRPF8 | pre-mRNA processing factor 8 | 0.035918 |
| TXNIP | thioredoxin interacting protein | 0.0358233 |
| SPAG9 | sperm associated antigen 9 | 0.0354043 |
| KLHL5 | kelch-like family member 5 | 0.0354002 |
| ETNK1 | ethanolamine kinase 1 | 0.035387 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0351781 |
| MKI67 | marker of proliferation Ki-67 | 0.0351597 |
| TMEM165 | transmembrane protein 165 | 0.0350451 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0350317 |
| NEK7 | NIMA-related kinase 7 | 0.0347718 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0346963 |
| PTMA | prothymosin, alpha | 0.0346869 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.034517 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0334853 |
| NUP58 | nucleoporin 58 | 0.0333416 |
| FAT1 | FAT atypical cadherin 1 | 0.033271 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0328978 |
| APP | amyloid beta (A4) precursor protein | 0.0327086 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0326744 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0325609 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0324926 |
| OGA | O-GlcNAcase | 0.0323857 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.032196 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0321755 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0321065 |
| AHR | aryl hydrocarbon receptor | 0.0314756 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0313513 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0311522 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0311266 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0310333 |
| WDR45B | WD repeat domain 45B | 0.0308828 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0307947 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0307546 |
| TFG | TRK-fused gene | 0.0306102 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0305007 |
| CDC73 | cell division cycle 73 | 0.0300137 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0298721 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0297957 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0296633 |
| RBM39 | RNA binding motif protein 39 | 0.0295839 |
| ZFR | zinc finger RNA binding protein | 0.0295505 |
| SRPK2 | SRSF protein kinase 2 | 0.0295366 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0294961 |
| KIF5B | kinesin family member 5B | 0.0293372 |
| ETV6 | ets variant 6 | 0.0292846 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0291169 |
| CLTC | clathrin, heavy chain (Hc) | 0.0286013 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0285126 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0284969 |
| WDR26 | WD repeat domain 26 | 0.0283178 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0281558 |
| FAM13A | family with sequence similarity 13, member A | 0.0281249 |
| PELO | pelota homolog (Drosophila) | 0.0281223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.210599 |
| HMGA2 | high mobility group AT-hook 2 | -0.112014 |
| FN1 | fibronectin 1 | -0.109888 |
| VCL | vinculin | -0.0702188 |
| INTS6 | integrator complex subunit 6 | -0.0641994 |
| TMSB10 | thymosin beta 10 | -0.0524137 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0510184 |
| AEBP2 | AE binding protein 2 | -0.0501089 |
| ASPH | aspartate beta-hydroxylase | -0.0467691 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.042752 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0427438 |
| FTL | ferritin, light polypeptide | -0.0411149 |
| RAI14 | retinoic acid induced 14 | -0.0389414 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0378015 |
| LRRC23 | leucine rich repeat containing 23 | -0.0356267 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0352036 |
| HLA-B | major histocompatibility complex, class I, B | -0.0344496 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0334158 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.033404 |
| IER3 | immediate early response 3 | -0.0319819 |
| SQSTM1 | sequestosome 1 | -0.0317288 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0315276 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.030312 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0293834 |
| TENM4 | teneurin transmembrane protein 4 | -0.0284835 |
| ACTG1 | actin gamma 1 | -0.0279102 |
| SYT1 | synaptotagmin I | -0.0274791 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0258894 |
| PALLD | palladin, cytoskeletal associated protein | -0.0252787 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0252658 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0239169 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0237834 |
| CCDC138 | coiled-coil domain containing 138 | -0.0236413 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0229327 |
| EGR1 | early growth response 1 | -0.0226443 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0223612 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.022287 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0222339 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0221712 |
| MYOF | myoferlin | -0.0213388 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0210702 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0210137 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0209636 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0208018 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0205571 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0205318 |
| TGFB1 | transforming growth factor, beta 1 | -0.0201633 |
| TUFT1 | tuftelin 1 | -0.020104 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0199264 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0194622 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0194278 |
| DPYD | dihydropyrimidine dehydrogenase | -0.01936 |
| NABP1 | nucleic acid binding protein 1 | -0.0193298 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0192529 |
| PRKCA | protein kinase C, alpha | -0.0192467 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0189195 |
| RPL38 | ribosomal protein L38 | -0.018904 |
| STC2 | stanniocalcin 2 | -0.0186214 |
| NBEA | neurobeachin | -0.0185754 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0183925 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0182877 |
| GPC6 | glypican 6 | -0.0182187 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.017932 |
| POU2F2 | POU class 2 homeobox 2 | -0.0176343 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0171531 |
| RPS29 | ribosomal protein S29 | -0.0170739 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0167415 |
| CUX1 | cut-like homeobox 1 | -0.0166569 |
| PDLIM5 | PDZ and LIM domain 5 | -0.01657 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0163111 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0162508 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0160597 |
| FBN1 | fibrillin 1 | -0.0158815 |
| RPL31 | ribosomal protein L31 | -0.0157552 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0157298 |
| PCNX4 | pecanex 4 | -0.0149887 |
| FHIT | fragile histidine triad | -0.0148801 |
| CADM1 | cell adhesion molecule 1 | -0.0148526 |
| FERMT2 | fermitin family member 2 | -0.0148136 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0147049 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0146847 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0146314 |
| RPL35A | ribosomal protein L35a | -0.014595 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0145127 |
| ITGA1 | integrin, alpha 1 | -0.0143449 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0142948 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0142753 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0142692 |
| LOX | lysyl oxidase | -0.0141997 |
| ACOXL | acyl-CoA oxidase-like | -0.0141747 |
| RAD51B | RAD51 paralog B | -0.0140804 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0140287 |
| MCL1 | myeloid cell leukemia 1 | -0.0139335 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0138285 |
| HOMER1 | homer scaffolding protein 1 | -0.0136834 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0133427 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0133055 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0132948 |
| NPAS1 | neuronal PAS domain protein 1 | -0.0132678 |
| GPATCH2L | G patch domain containing 2-like | -0.0132206 |
