Epsilon DNA polymerase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair. (Gene Ontology, GO_0008622)
External Link http://amigo.geneontology.org/amigo/term/GO:0008622
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1000 proteins co-occuring with the Epsilon DNA polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
POLE polymerase (DNA directed), epsilon, catalytic subunit 3.868
CDC45 cell division cycle 45 3.403
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 3.327
WDHD1 WD repeat and HMG-box DNA binding protein 1 3.232
PCNA proliferating cell nuclear antigen 3.216
POLL polymerase (DNA directed), lambda 3.153
MCM10 minichromosome maintenance complex component 10 3.146
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 3.069
TOPBP1 topoisomerase (DNA) II binding protein 1 3.038
TICRR TOPBP1-interacting checkpoint and replication regulator 3.028
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 3.025
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 3.009
POLM polymerase (DNA directed), mu 3.002
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 2.953
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 2.95
FEN1 flap structure-specific endonuclease 1 2.949
MSH6 mutS homolog 6 2.917
GINS4 GINS complex subunit 4 (Sld5 homolog) 2.897
REV1 REV1, polymerase (DNA directed) 2.868
CDT1 chromatin licensing and DNA replication factor 1 2.797
DBF4 DBF4 zinc finger 2.796
MSH2 mutS homolog 2 2.796
EXO1 exonuclease 1 2.772
CDC6 cell division cycle 6 2.766
GINS3 GINS complex subunit 3 (Psf3 homolog) 2.755
MLH1 mutL homolog 1 2.719
MCM4 minichromosome maintenance complex component 4 2.713
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.706
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 2.686
CLSPN claspin 2.664
PRIMPOL primase and polymerase (DNA-directed) 2.653
POLD2 polymerase (DNA directed), delta 2, accessory subunit 2.643
TENT4A terminal nucleotidyltransferase 4A 2.619
DNA2 DNA replication helicase/nuclease 2 2.617
MSH3 mutS homolog 3 2.595
RAD18 RAD18 E3 ubiquitin protein ligase 2.583
TIPIN TIMELESS interacting protein 2.573
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.555
MCM6 minichromosome maintenance complex component 6 2.535
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 2.505
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 2.497
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.491
ERCC1 excision repair cross-complementation group 1 2.479
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 2.478
XPA xeroderma pigmentosum, complementation group A 2.477
CHEK2 checkpoint kinase 2 2.47
TP53 tumor protein p53 2.457
DSCC1 DNA replication and sister chromatid cohesion 1 2.444
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 2.443
POLH polymerase (DNA directed), eta 2.443
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 2.436
RAD52 RAD52 homolog (S. cerevisiae) 2.432
TOP1 topoisomerase (DNA) I 2.432
ERCC2 excision repair cross-complementation group 2 2.43
TIMELESS timeless circadian clock 2.421
MCM5 minichromosome maintenance complex component 5 2.42
PIF1 PIF1 5'-to-3' DNA helicase 2.414
RAD51 RAD51 recombinase 2.412
CDC7 cell division cycle 7 2.411
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2.404
PRIM1 primase, DNA, polypeptide 1 (49kDa) 2.402
RAD17 RAD17 homolog (S. pombe) 2.396
RAD23B RAD23 homolog B (S. cerevisiae) 2.382
CHEK1 checkpoint kinase 1 2.381
ATAD5 ATPase family, AAA domain containing 5 2.378
BRCA2 breast cancer 2, early onset 2.35
ERCC3 excision repair cross-complementation group 3 2.348
MCM3 minichromosome maintenance complex component 3 2.344
BRCA1 breast cancer 1, early onset 2.343
RFC2 replication factor C (activator 1) 2, 40kDa 2.338
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.323
RAD9A RAD9 homolog A (S. pombe) 2.307
ATM ATM serine/threonine kinase 2.305
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.303
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 2.285
MUTYH mutY homolog 2.285
RECQL4 RecQ protein-like 4 2.266
OGG1 8-oxoguanine DNA glycosylase 2.263
PRIM2 primase, DNA, polypeptide 2 (58kDa) 2.25
CD274 CD274 molecule 2.211
RAD50 RAD50 homolog (S. cerevisiae) 2.201
BRIP1 BRCA1 interacting protein C-terminal helicase 1 2.196
NTHL1 nth endonuclease III-like 1 (E. coli) 2.17
MRC1 mannose receptor, C type 1 2.145
WRN Werner syndrome, RecQ helicase-like 2.142
MUS81 MUS81 structure-specific endonuclease subunit 2.137
ATRIP ATR interacting protein 2.136
HUS1 HUS1 checkpoint homolog (S. pombe) 2.136
ARID1A AT rich interactive domain 1A (SWI-like) 2.133
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.099
FANCM Fanconi anemia, complementation group M 2.096
MLH3 mutL homolog 3 2.092
RFC3 replication factor C (activator 1) 3, 38kDa 2.085
UNG uracil-DNA glycosylase 2.083
APTX aprataxin 2.082
HLTF helicase-like transcription factor 2.081
PNKP polynucleotide kinase 3'-phosphatase 2.077
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 2.074
RFC4 replication factor C (activator 1) 4, 37kDa 2.072
H2AC20 H2A clustered histone 20 2.066
DDB2 damage-specific DNA binding protein 2, 48kDa 2.065
H2AC19 H2A clustered histone 19 2.063
RTEL1 regulator of telomere elongation helicase 1 2.047
POLI polymerase (DNA directed) iota 2.042
PARP1 poly (ADP-ribose) polymerase 1 2.033
NEIL3 nei endonuclease VIII-like 3 (E. coli) 2.024
PRKDC protein kinase, DNA-activated, catalytic polypeptide 2.021
MTBP MDM2 binding protein 2.016
DONSON downstream neighbor of SON 2.01
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.009
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 2.007
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.006
TDP1 tyrosyl-DNA phosphodiesterase 1 1.988
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.982
TP53BP1 tumor protein p53 binding protein 1 1.972
DDB1 damage-specific DNA binding protein 1, 127kDa 1.971
SSBP1 single-stranded DNA binding protein 1, mitochondrial 1.964
PTEN phosphatase and tensin homolog 1.954
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.948
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.947
H3-3B H3.3 histone B 1.922
ZRANB3 zinc finger, RAN-binding domain containing 3 1.913
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.91
PDCD1 programmed cell death 1 1.908
H3-5 H3.5 histone 1.907
FANCD2 Fanconi anemia, complementation group D2 1.906
H3-4 H3.4 histone, cluster member 1.906
H3-7 H3.7 histone (putative) 1.905
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 1.896
RECQL RecQ helicase-like 1.889
ERCC6 excision repair cross-complementation group 6 1.888
H2BC21 H2B clustered histone 21 1.886
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 1.883
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.869
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.86
WEE1 WEE1 G2 checkpoint kinase 1.853
CDK2 cyclin-dependent kinase 2 1.85
UBE2N ubiquitin-conjugating enzyme E2N 1.847
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.84
ORC6 origin recognition complex, subunit 6 1.836
PALB2 partner and localizer of BRCA2 1.827
POLN polymerase (DNA directed) nu 1.825
POLR1A polymerase (RNA) I polypeptide A, 194kDa 1.824
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.821
RAD51C RAD51 paralog C 1.817
TOP2A topoisomerase (DNA) II alpha 170kDa 1.809
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.808
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.804
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.801
USP1 ubiquitin specific peptidase 1 1.8
RMI1 RecQ mediated genome instability 1 1.789
TOP3A topoisomerase (DNA) III alpha 1.789
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.787
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.778
SLX4 SLX4 structure-specific endonuclease subunit 1.771
RNASEH2A ribonuclease H2, subunit A 1.767
ORC4 origin recognition complex, subunit 4 1.758
RPA3 replication protein A3, 14kDa 1.751
CD8A CD8a molecule 1.745
FANCI Fanconi anemia, complementation group I 1.74
EME1 essential meiotic structure-specific endonuclease 1 1.74
RBBP8 retinoblastoma binding protein 8 1.732
ERBB2 erb-b2 receptor tyrosine kinase 2 1.723
SRSF1 serine/arginine-rich splicing factor 1 1.715
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.712
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 1.708
TRAIP TRAF interacting protein 1.702
STN1 STN1 subunit of CST complex 1.699
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.693
ORC5 origin recognition complex, subunit 5 1.693
XPC xeroderma pigmentosum, complementation group C 1.685
TDG thymine-DNA glycosylase 1.681
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.679
RECQL5 RecQ protein-like 5 1.678
NHEJ1 nonhomologous end-joining factor 1 1.673
CDC20 cell division cycle 20 1.67
UVSSA UV-stimulated scaffold protein A 1.667
SPRTN SprT-like N-terminal domain 1.667
LIG4 ligase IV, DNA, ATP-dependent 1.665
RNASEH2B ribonuclease H2, subunit B 1.663
H2AX H2A.X variant histone 1.663
CCNA2 cyclin A2 1.662
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 1.658
CETN2 centrin, EF-hand protein, 2 1.658
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.656
LRR1 leucine rich repeat protein 1 1.653
SMC5 structural maintenance of chromosomes 5 1.653
CCNA1 cyclin A1 1.647
CHRAC1 chromatin accessibility complex 1 1.646
DNAH8 dynein, axonemal, heavy chain 8 1.646
SMC3 structural maintenance of chromosomes 3 1.646
ETAA1 Ewing tumor-associated antigen 1 1.638
CDK1 cyclin-dependent kinase 1 1.635
DIAPH2 diaphanous-related formin 2 1.63
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 1.621
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 1.616
XAB2 XPA binding protein 2 1.615
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.608
FANCA Fanconi anemia, complementation group A 1.606
ERCC4 excision repair cross-complementation group 4 1.598
RNASEH1 ribonuclease H1 1.592
FBH1 F-box DNA helicase 1 1.592
RAD54B RAD54 homolog B (S. cerevisiae) 1.59
NEIL2 nei endonuclease VIII-like 2 (E. coli) 1.588
CCNL2 cyclin L2 1.588
MGMT O-6-methylguanine-DNA methyltransferase 1.587
PARP2 poly (ADP-ribose) polymerase 2 1.585
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.582
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.574
EGFR epidermal growth factor receptor 1.568
MMS22L MMS22-like, DNA repair protein 1.539
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid 1.533
ERCC8 excision repair cross-complementation group 8 1.518
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.513
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 1.506
GTF2H5 general transcription factor IIH, polypeptide 5 1.499
PDCD1LG2 programmed cell death 1 ligand 2 1.496
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.496
CUL4A cullin 4A 1.493
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 1.492
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.49
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.489
MBD4 methyl-CpG binding domain protein 4 1.488
RNASEH2C ribonuclease H2, subunit C 1.485
TERT telomerase reverse transcriptase 1.48
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.479
L1CAM L1 cell adhesion molecule 1.478
MCM8 minichromosome maintenance complex component 8 1.477
ASF1A anti-silencing function 1A histone chaperone 1.475
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 1.474
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.469
MCM7 minichromosome maintenance complex component 7 1.457
SMAD4 SMAD family member 4 1.453
SEPTIN7 septin 7 1.451
CDC27 cell division cycle 27 1.444
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.439
RNF43 ring finger protein 43 1.439
UBE2I ubiquitin-conjugating enzyme E2I 1.436
KMT5A lysine methyltransferase 5A 1.434
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 1.43
TONSL tonsoku-like, DNA repair protein 1.429
ASF1B anti-silencing function 1B histone chaperone 1.428
CDKN2A cyclin-dependent kinase inhibitor 2A 1.428
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1.426
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.42
REEP5 receptor accessory protein 5 1.415
LAG3 lymphocyte-activation gene 3 1.401
H2AZ1 H2A.Z variant histone 1 1.4
RAD51D RAD51 paralog D 1.396
BARD1 BRCA1 associated RING domain 1 1.396
SIRT2 sirtuin 2 1.39
RAD21 RAD21 homolog (S. pombe) 1.388
ORC3 origin recognition complex, subunit 3 1.388
EME2 essential meiotic structure-specific endonuclease subunit 2 1.386
CIAO1 cytosolic iron-sulfur assembly component 1 1.385
MDC1 mediator of DNA-damage checkpoint 1 1.382
MPG N-methylpurine-DNA glycosylase 1.379
ARID5B AT rich interactive domain 5B (MRF1-like) 1.378
FANCC Fanconi anemia, complementation group C 1.376
WDR48 WD repeat domain 48 1.373
CHD7 chromodomain helicase DNA binding protein 7 1.373
FBF1 Fas (TNFRSF6) binding factor 1 1.372
MCM9 minichromosome maintenance complex component 9 1.371
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 1.37
MMUT methylmalonyl-CoA mutase 1.369
UBE2K ubiquitin-conjugating enzyme E2K 1.366
CDK4 cyclin-dependent kinase 4 1.365
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 1.363
RADX RPA1 related single stranded DNA binding protein, X-linked 1.36
NIPBL Nipped-B homolog (Drosophila) 1.359
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 1.356
ESR1 estrogen receptor 1 1.356
PGR progesterone receptor 1.355
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.354
FOXN2 forkhead box N2 1.353
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa 1.351
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.35
CDC25A cell division cycle 25A 1.348
VCP valosin containing protein 1.347
DIAPH3 diaphanous-related formin 3 1.346
CD4 CD4 molecule 1.341
H3C7 H3 clustered histone 7 1.341
CDK12 cyclin-dependent kinase 12 1.337
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.336
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 1.335
TDP2 tyrosyl-DNA phosphodiesterase 2 1.333
SDE2 SDE2 telomere maintenance homolog (S. pombe) 1.33
CTC1 CTS telomere maintenance complex component 1 1.329
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.329
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.327
STK11 serine/threonine kinase 11 1.326
GINS2 GINS complex subunit 2 (Psf2 homolog) 1.322
CUL2 cullin 2 1.321
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.319
CTCF CCCTC-binding factor (zinc finger protein) 1.318
APLF aprataxin and PNKP like factor 1.315
DCLRE1A DNA cross-link repair 1A 1.314
CIAPIN1 cytokine induced apoptosis inhibitor 1 1.314
BLM Bloom syndrome, RecQ helicase-like 1.312
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.309
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 1.306
RAD51B RAD51 paralog B 1.301
SETD2 SET domain containing 2 1.301
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.301
DHH desert hedgehog 1.296
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1.294
POLK polymerase (DNA directed) kappa 1.292
CCNE1 cyclin E1 1.292
SETX senataxin 1.288
TBCE tubulin folding cofactor E 1.288
E2F1 E2F transcription factor 1 1.283
ARTN artemin 1.281
FGFR2 fibroblast growth factor receptor 2 1.279
SIVA1 SIVA1, apoptosis-inducing factor 1.279
RGPD3 RANBP2-like and GRIP domain containing 3 1.269
FANCE Fanconi anemia, complementation group E 1.267
SIRT1 sirtuin 1 1.267
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.266
NUBP2 nucleotide binding protein 2 1.264
CLSTN1 calsyntenin 1 1.262
H4C15 H4 clustered histone 15 1.262
FAAP24 FA core complex associated protein 24 1.259
SCAI suppressor of cancer cell invasion 1.258
IDO1 indoleamine 2,3-dioxygenase 1 1.254
TFF2 trefoil factor 2 1.253
CDC34 cell division cycle 34 1.25
FANCG Fanconi anemia, complementation group G 1.248
FANCL Fanconi anemia, complementation group L 1.244
CDPF1 cysteine-rich, DPF motif domain containing 1 1.243
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.242
HAVCR2 hepatitis A virus cellular receptor 2 1.24
FANCF Fanconi anemia, complementation group F 1.24
ACVR2A activin A receptor, type IIA 1.234
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.234
PARG poly (ADP-ribose) glycohydrolase 1.229
NAE1 NEDD8 activating enzyme E1 subunit 1 1.228
UBE2M ubiquitin-conjugating enzyme E2M 1.228
TWNK twinkle mtDNA helicase 1.227
H4C7 H4 clustered histone 7 1.223
IFNG interferon, gamma 1.221
HROB homologous recombination factor with OB-fold 1.214
EPCAM epithelial cell adhesion molecule 1.213
MCMBP minichromosome maintenance complex binding protein 1.212
IGHMBP2 immunoglobulin mu binding protein 2 1.211
DAXX death-domain associated protein 1.208
WRNIP1 Werner helicase interacting protein 1 1.208
TYMS thymidylate synthetase 1.204
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.204
CENPA centromere protein A 1.204
RPL22 ribosomal protein L22 1.203
PDS5A PDS5 cohesin associated factor A 1.203
NF1 neurofibromin 1 1.202
NDC80 NDC80 kinetochore complex component 1.199
PIAS2 protein inhibitor of activated STAT, 2 1.197
SMC6 structural maintenance of chromosomes 6 1.197
WWOX WW domain containing oxidoreductase 1.192
PCLAF PCNA clamp associated factor 1.192
PLK1 polo-like kinase 1 1.19
TOP1MT topoisomerase (DNA) I, mitochondrial 1.183
MSH5 mutS homolog 5 1.182
MRE11 MRE11 homolog, double strand break repair nuclease 1.18
H2BC5 H2B clustered histone 5 1.171
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 1.17
MSH4 mutS homolog 4 1.17
CIAO2B cytosolic iron-sulfur assembly component 2B 1.162
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.161
TGFB1 transforming growth factor, beta 1 1.161
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 1.161
GMNN geminin, DNA replication inhibitor 1.159
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.158
ZNF629 zinc finger protein 629 1.157
ZNF763 zinc finger protein 763 1.156
ZNF44 zinc finger protein 44 1.156
ZNF501 zinc finger protein 501 1.156
H2BC4 H2B clustered histone 4 1.156
ZNF436 zinc finger protein 436 1.155
ZNF569 zinc finger protein 569 1.153
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.15
CIAO3 cytosolic iron-sulfur assembly component 3 1.15
ADCY10 adenylate cyclase 10 (soluble) 1.148
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.146
RFWD3 ring finger and WD repeat domain 3 1.146
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.141
PBRM1 polybromo 1 1.136
H2BC9 H2B clustered histone 9 1.131
H2BC14 H2B clustered histone 14 1.131
FAAP20 FA core complex associated protein 20 1.13
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.129
EP300 E1A binding protein p300 1.126
H2BC3 H2B clustered histone 3 1.126
H2BC11 H2B clustered histone 11 1.125
CHD4 chromodomain helicase DNA binding protein 4 1.124
OR3A3 olfactory receptor, family 3, subfamily A, member 3 1.123
TCEA1 transcription elongation factor A (SII), 1 1.122
ZGRF1 zinc finger, GRF-type containing 1 1.122
H2BK1 H2B.K variant histone 1 1.116
TCEA2 transcription elongation factor A (SII), 2 1.115
H2BC1 H2B clustered histone 1 1.115
H2BW1 H2B.W histone 1 1.114
H2BW2 H2B.W histone 2 1.114
H2BC12L H2B clustered histone 12 like 1.114
HDAC1 histone deacetylase 1 1.113
CCND1 cyclin D1 1.113
SRCAP Snf2-related CREBBP activator protein 1.112
H2BC13 H2B clustered histone 13 1.112
H2BC18 H2B clustered histone 18 1.111
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.11
ZNF2 zinc finger protein 2 1.11
H2BC17 H2B clustered histone 17 1.109
H2BC26 H2B clustered histone 26 1.109
TCEA3 transcription elongation factor A (SII), 3 1.106
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.106
H2BC15 H2B clustered histone 15 1.106
CBX8 chromobox homolog 8 1.104
FOXP3 forkhead box P3 1.103
TK2 thymidine kinase 2, mitochondrial 1.102
ZNF274 zinc finger protein 274 1.101
H2BC12 H2B clustered histone 12 1.101
FHIT fragile histidine triad 1.098
BMPR1A bone morphogenetic protein receptor, type IA 1.098
FAAP100 FA core complex associated protein 100 1.098
NFS1 NFS1 cysteine desulfurase 1.094
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.094
RAD54L RAD54-like (S. cerevisiae) 1.092
KAT2B K(lysine) acetyltransferase 2B 1.092
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.092
UHRF1 ubiquitin-like with PHD and ring finger domains 1 1.089
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.089
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1.088
CDA cytidine deaminase 1.087
CCNH cyclin H 1.086
POTEF POTE ankyrin domain family, member F 1.084
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.084
UBE2T ubiquitin-conjugating enzyme E2T 1.084
OR1S2 olfactory receptor, family 1, subfamily S, member 2 1.083
MAGEA4 melanoma antigen family A4 1.083
ALK anaplastic lymphoma receptor tyrosine kinase 1.083
IPO4 importin 4 1.08
TCHP trichoplein, keratin filament binding 1.076
LOC112267897 keratin-associated protein 21-1-like 1.073
DHFR dihydrofolate reductase 1.071
PAXX PAXX non-homologous end joining factor 1.071
AURKB aurora kinase B 1.07
KAT2A K(lysine) acetyltransferase 2A 1.07
SETD1A SET domain containing 1A 1.068
TOP2B topoisomerase (DNA) II beta 180kDa 1.068
OR5M8 olfactory receptor, family 5, subfamily M, member 8 1.068
KMT2C lysine (K)-specific methyltransferase 2C 1.065
KMT2D lysine (K)-specific methyltransferase 2D 1.064
UBA1 ubiquitin-like modifier activating enzyme 1 1.058
CUL1 cullin 1 1.058
HRAS Harvey rat sarcoma viral oncogene homolog 1.055
AICDA activation-induced cytidine deaminase 1.053
TTK TTK protein kinase 1.051
DLL3 delta-like 3 (Drosophila) 1.047
GEN1 GEN1 Holliday junction 5' flap endonuclease 1.046
LAMC3 laminin, gamma 3 1.043
SKP1 S-phase kinase-associated protein 1 1.042
CKS1B CDC28 protein kinase regulatory subunit 1B 1.041
SMC1A structural maintenance of chromosomes 1A 1.041
CCNE2 cyclin E2 1.041
NAV2 neuron navigator 2 1.039
GMNC geminin coiled-coil domain containing 1.037
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 1.034
FSBP fibrinogen silencer binding protein 1.034
SSRP1 structure specific recognition protein 1 1.032
HDAC9 histone deacetylase 9 1.028
JAK1 Janus kinase 1 1.023
PXDNL peroxidasin-like 1.021
TBL1X transducin (beta)-like 1X-linked 1.021
RRM2 ribonucleotide reductase M2 1.02
PXDN peroxidasin 1.02
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.019
UIMC1 ubiquitin interaction motif containing 1 1.019
H1-0 H1.0 linker histone 1.016
PMEPA1 prostate transmembrane protein, androgen induced 1 1.009
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.005
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.005
SETDB1 SET domain, bifurcated 1 1.004
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 1.003
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 1.003
CCNB1 cyclin B1 1.002
MNAT1 MNAT CDK-activating kinase assembly factor 1 1.002
FOXM1 forkhead box M1 1.0
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.999
DLL4 delta-like 4 (Drosophila) 0.998
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.992
KAT7 K(lysine) acetyltransferase 7 0.992
HELB helicase (DNA) B 0.99
RET ret proto-oncogene 0.99
RTF2 replication termination factor 2 0.988
MAT2A methionine adenosyltransferase II, alpha 0.987
AURKA aurora kinase A 0.987
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.986
HELQ helicase, POLQ-like 0.985
SPO11 SPO11 meiotic protein covalently bound to DSB 0.984
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.983
LGALS4 lectin, galactoside-binding, soluble, 4 0.982
CCNF cyclin F 0.979
PARP3 poly (ADP-ribose) polymerase family, member 3 0.979
AFAP1 actin filament associated protein 1 0.978
DICER1 dicer 1, ribonuclease type III 0.977
TIGIT T cell immunoreceptor with Ig and ITIM domains 0.974
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 0.974
HMGN1 high mobility group nucleosome binding domain 1 0.973
VTCN1 V-set domain containing T cell activation inhibitor 1 0.971
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.971
WAPL WAPL cohesin release factor 0.971
ZFHX3 zinc finger homeobox 3 0.967
CHD1 chromodomain helicase DNA binding protein 1 0.967
DOT1L DOT1-like histone H3K79 methyltransferase 0.966
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.966
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.965
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 0.965
BUB3 BUB3 mitotic checkpoint protein 0.963
LIN9 lin-9 DREAM MuvB core complex component 0.963
CUL4B cullin 4B 0.962
HJURP Holliday junction recognition protein 0.961
BOD1L1 biorientation of chromosomes in cell division 1-like 1 0.959
AMER1 APC membrane recruitment protein 1 0.958
ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 0.956
PHGDH phosphoglycerate dehydrogenase 0.955
CDK6 cyclin-dependent kinase 6 0.955
UXT ubiquitously-expressed, prefoldin-like chaperone 0.953
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.952
MUC16 mucin 16, cell surface associated 0.95
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.949
CDK7 cyclin-dependent kinase 7 0.947
PGK1 phosphoglycerate kinase 1 0.946
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.946
GATAD2B GATA zinc finger domain containing 2B 0.945
FXN frataxin 0.944
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 0.941
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 0.94
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.935
PIAS4 protein inhibitor of activated STAT, 4 0.933
SMC1B structural maintenance of chromosomes 1B 0.933
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.932
CGAS cyclic GMP-AMP synthase 0.932
CD28 CD28 molecule 0.931
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.93
FGFR1 fibroblast growth factor receptor 1 0.93
RMI2 RecQ mediated genome instability 2 0.929
RNF4 ring finger protein 4 0.924
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.923
OR10H3 olfactory receptor, family 10, subfamily H, member 3 0.923
BCL2 B-cell CLL/lymphoma 2 0.922
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.921
SUMO1 small ubiquitin-like modifier 1 0.92
HDAC8 histone deacetylase 8 0.914
RNF32 ring finger protein 32 0.914
PTPRQ protein tyrosine phosphatase, receptor type, Q 0.91
FGFR3 fibroblast growth factor receptor 3 0.909
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.908
CDC25C cell division cycle 25C 0.908
CSMD3 CUB and Sushi multiple domains 3 0.908
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 0.907
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.907
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.906
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.906
SHLD1 shieldin complex subunit 1 0.905
GADD45A growth arrest and DNA-damage-inducible, alpha 0.904
SUGP1 SURP and G patch domain containing 1 0.904
FLII flightless I homolog (Drosophila) 0.903
KIAA1671 KIAA1671 0.903
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.902
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.902
PIAS1 protein inhibitor of activated STAT, 1 0.9
CDC14A cell division cycle 14A 0.9
ARID1B AT rich interactive domain 1B (SWI1-like) 0.9
RAD51AP1 RAD51 associated protein 1 0.896
RCC1 regulator of chromosome condensation 1 0.896
LMNB1 lamin B1 0.892
OR6Q1 olfactory receptor, family 6, subfamily Q, member 1 (gene/pseudogene) 0.892
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.892
SAMHD1 SAM domain and HD domain 1 0.891
TXN2 thioredoxin 2 0.886
TBP TATA box binding protein 0.883
UBA3 ubiquitin-like modifier activating enzyme 3 0.882
AREG amphiregulin 0.881
GAN gigaxonin 0.881
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.88
WDR70 WD repeat domain 70 0.878
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 0.878
RAD23A RAD23 homolog A (S. cerevisiae) 0.877
KAT5 K(lysine) acetyltransferase 5 0.876
EGF epidermal growth factor 0.876
OXTR oxytocin receptor 0.875
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.873
MDM4 MDM4, p53 regulator 0.873
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.872
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.871
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 0.87
RNF2 ring finger protein 2 0.869
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.868
CENPS-CORT CENPS-CORT readthrough 0.868
HDAC2 histone deacetylase 2 0.867
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 0.865
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.864
DGUOK deoxyguanosine kinase 0.863
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.862
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.861
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.858
NDOR1 NADPH dependent diflavin oxidoreductase 1 0.855
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.855
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.855
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.854
BIRC5 baculoviral IAP repeat containing 5 0.853
FAF1 Fas (TNFRSF6) associated factor 1 0.852
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.851
SMC4 structural maintenance of chromosomes 4 0.849
ERBB3 erb-b2 receptor tyrosine kinase 3 0.849
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.849
NLRP4 NLR family, pyrin domain containing 4 0.846
MRNIP MRN complex interacting protein 0.846
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 0.845
CABIN1 calcineurin binding protein 1 0.845
FBRSL1 fibrosin-like 1 0.842
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 0.842
RBM24 RNA binding motif protein 24 0.84
ERCC5 excision repair cross-complementation group 5 0.84
JUN jun proto-oncogene 0.839
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.839
FBXO5 F-box protein 5 0.836
HOXD13 homeobox D13 0.835
IL2 interleukin 2 0.835
ALKBH5 AlkB family member 5, RNA demethylase 0.835
CXCL9 chemokine (C-X-C motif) ligand 9 0.833
NME1-NME2 NME1-NME2 readthrough 0.832
OR1N1 olfactory receptor, family 1, subfamily N, member 1 0.83
SENP6 SUMO1/sentrin specific peptidase 6 0.829
MPPE1 metallophosphoesterase 1 0.828
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.827
CDK8 cyclin-dependent kinase 8 0.825
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 0.824
TNF tumor necrosis factor 0.824
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.824
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 0.823
OR6C4 olfactory receptor, family 6, subfamily C, member 4 0.823
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.817
SEPTIN3 septin 3 0.817
BAX BCL2-associated X protein 0.814
RBM10 RNA binding motif protein 10 0.813
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.813
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.812
CENPF centromere protein F, 350/400kDa 0.811
ZUP1 zinc finger containing ubiquitin peptidase 1 0.811
CETN3 centrin, EF-hand protein, 3 0.808
METTL3 methyltransferase like 3 0.808
CALML3 calmodulin-like 3 0.807
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.807
OR10A7 olfactory receptor, family 10, subfamily A, member 7 0.806
DNTT DNA nucleotidylexotransferase 0.805
MAP6 microtubule-associated protein 6 0.803
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.803
CCNG1 cyclin G1 0.803
CD68 CD68 molecule 0.801
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 0.801
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 0.8
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.799
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.797
UBA2 ubiquitin-like modifier activating enzyme 2 0.797
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.797
TERF2IP telomeric repeat binding factor 2, interacting protein 0.797
P3H1 prolyl 3-hydroxylase 1 0.797
CALML6 calmodulin-like 6 0.794
CALML4 calmodulin-like 4 0.794
CALML5 calmodulin-like 5 0.793
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.793
CD80 CD80 molecule 0.791
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.791
LRP1B low density lipoprotein receptor-related protein 1B 0.79
ENDOV endonuclease V 0.789
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.789
FAM83B family with sequence similarity 83, member B 0.788
SHLD2 shieldin complex subunit 2 0.788
HAT1 histone acetyltransferase 1 0.787
GREM1 gremlin 1, DAN family BMP antagonist 0.783
DEDD death effector domain containing 0.782
IRF1 interferon regulatory factor 1 0.782
POLRMT polymerase (RNA) mitochondrial (DNA directed) 0.781
SAMD9 sterile alpha motif domain containing 9 0.779
TRRAP transformation/transcription domain-associated protein 0.779
CENPX centromere protein X 0.779
LMNB2 lamin B2 0.777
ZBTB1 zinc finger and BTB domain containing 1 0.777
UBE2H ubiquitin-conjugating enzyme E2H 0.776
ATMIN ATM interactor 0.775
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.774
TERF2 telomeric repeat binding factor 2 0.772
MYB v-myb avian myeloblastosis viral oncogene homolog 0.772
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.77
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.769
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.767
NASP nuclear autoantigenic sperm protein (histone-binding) 0.766
AXIN2 axin 2 0.766
HELLS helicase, lymphoid-specific 0.766
UBXN7 UBX domain protein 7 0.764
EAPP E2F-associated phosphoprotein 0.764
ASTE1 asteroid homolog 1 (Drosophila) 0.763
KMT2A lysine (K)-specific methyltransferase 2A 0.763
CDKN3 cyclin-dependent kinase inhibitor 3 0.761
NCAPD2 non-SMC condensin I complex, subunit D2 0.761
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component 0.76
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.758
CIZ1 CDKN1A interacting zinc finger protein 1 0.758
UBE2C ubiquitin-conjugating enzyme E2C 0.757
IFNW1 interferon, omega 1 0.756
OR4D5 olfactory receptor, family 4, subfamily D, member 5 0.755
RNF7 ring finger protein 7 0.754
FAT4 FAT atypical cadherin 4 0.753
CD86 CD86 molecule 0.752
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.752
FAT1 FAT atypical cadherin 1 0.751
IL6 interleukin 6 0.751
OR56A4 olfactory receptor, family 56, subfamily A, member 4 0.75
OR5D14 olfactory receptor, family 5, subfamily D, member 14 0.749
UBE2A ubiquitin-conjugating enzyme E2A 0.749
FANCB Fanconi anemia, complementation group B 0.748
DCLRE1B DNA cross-link repair 1B 0.748
CREBBP CREB binding protein 0.748
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.746
DCK deoxycytidine kinase 0.745
TMC6 transmembrane channel-like 6 0.743
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.742
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.741
TMSB15C thymosin beta 15C 0.741
SLC38A3 solute carrier family 38, member 3 0.74
SMAD9 SMAD family member 9 0.74
CHD6 chromodomain helicase DNA binding protein 6 0.74
REXO2 RNA exonuclease 2 0.74
MAU2 MAU2 sister chromatid cohesion factor 0.739
UFD1 ubiquitin recognition factor in ER associated degradation 1 0.739
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.736
CCR8 chemokine (C-C motif) receptor 8 0.736
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.736
GNAS GNAS complex locus 0.734
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.733
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 0.733
SEM1 SEM1 26S proteasome subunit 0.733
WDR87 WD repeat domain 87 0.731
TSPYL5 TSPY-like 5 0.73
NFYB nuclear transcription factor Y, beta 0.729
RRM1 ribonucleotide reductase M1 0.729
HDAC3 histone deacetylase 3 0.728
SLC35G6 solute carrier family 35, member G6 0.728
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.726
CKMT1B creatine kinase, mitochondrial 1B 0.726
DRC11 dynein regulatory complex subunit 11 0.725
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 0.724
H3C13 H3 clustered histone 13 0.724
CBR4 carbonyl reductase 4 0.722
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.722
KRTAP9-9 keratin associated protein 9-9 0.721
CKB creatine kinase, brain 0.721
RPS20 ribosomal protein S20 0.72
ELOB elongin B 0.72
CDCA5 cell division cycle associated 5 0.719
CKM creatine kinase, muscle 0.718
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.717
UBE2S ubiquitin-conjugating enzyme E2S 0.717
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 0.716
SMAD2 SMAD family member 2 0.716
OBI1 ORC ubiquitin ligase 1 0.716
CIP2A cellular inhibitor of PP2A 0.714
TSPYL1 TSPY-like 1 0.713
CHKA choline kinase alpha 0.713
INS insulin 0.713
ACVR1B activin A receptor, type IB 0.713
OR5AR1 olfactory receptor, family 5, subfamily AR, member 1 (gene/pseudogene) 0.71
RASAL3 RAS protein activator like 3 0.71
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.709
TREX1 three prime repair exonuclease 1 0.706
PAX8 paired box 8 0.705
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.705
ERI3 ERI1 exoribonuclease family member 3 0.705
IGF1 insulin-like growth factor 1 (somatomedin C) 0.703
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.702
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.702
ELOA2 elongin A2 0.702
GTF3A general transcription factor IIIA 0.7
CD36 CD36 molecule (thrombospondin receptor) 0.7
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.7
TET1 tet methylcytosine dioxygenase 1 0.699
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.698
CCNO cyclin O 0.698
CSF1R colony stimulating factor 1 receptor 0.697
SLTM SAFB-like, transcription modulator 0.697
FIGNL1 fidgetin-like 1 0.696
KMT5B lysine methyltransferase 5B 0.696
CCNB2 cyclin B2 0.693
DPH1 diphthamide biosynthesis 1 0.692
OR10G2 olfactory receptor, family 10, subfamily G, member 2 0.69
JAK2 Janus kinase 2 0.689
OR10G8 olfactory receptor, family 10, subfamily G, member 8 0.689
LARP1 La ribonucleoprotein domain family, member 1 0.687
BIVM-ERCC5 BIVM-ERCC5 readthrough 0.686
IGF2 insulin-like growth factor 2 0.685
POLR1H RNA polymerase I subunit H 0.685
SPDL1 spindle apparatus coiled-coil protein 1 0.684
ZNF395 zinc finger protein 395 0.683
ANO1 anoctamin 1, calcium activated chloride channel 0.683
ELOC elongin C 0.683
PHF20 PHD finger protein 20 0.682
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.682
ZBED1 zinc finger, BED-type containing 1 0.682
FLT3 fms-related tyrosine kinase 3 0.682
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.681
LYRM4 LYR motif containing 4 0.681
PPP4R3B protein phosphatase 4 regulatory subunit 3B 0.68
CDC25B cell division cycle 25B 0.679
GRWD1 glutamate-rich WD repeat containing 1 0.679
ANXA5 annexin A5 0.675
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.675
DMAP1 DNA methyltransferase 1 associated protein 1 0.674
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 0.674
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.672
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.672
USP43 ubiquitin specific peptidase 43 0.672
POT1 protection of telomeres 1 0.671
HMGB1 high mobility group box 1 0.669
BFAR bifunctional apoptosis regulator 0.668
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 0.668
RRAD Ras-related associated with diabetes 0.666
TG thyroglobulin 0.665
SAPCD2 suppressor APC domain containing 2 0.665
B2M beta-2-microglobulin 0.664
ISG15 ISG15 ubiquitin-like modifier 0.663
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.662
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.662
NME6 NME/NM23 nucleoside diphosphate kinase 6 0.661
FOXO1 forkhead box O1 0.66
GTF2H2C GTF2H2 family member C 0.66
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.659
EP400 E1A binding protein p400 0.656
ERBB4 erb-b2 receptor tyrosine kinase 4 0.656
USP11 ubiquitin specific peptidase 11 0.655
BRD4 bromodomain containing 4 0.655
CD40 CD40 molecule, TNF receptor superfamily member 5 0.655
PCNX2 pecanex 2 0.654
CD276 CD276 molecule 0.653
TTC28 tetratricopeptide repeat domain 28 0.652
MGME1 mitochondrial genome maintenance exonuclease 1 0.652
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.652
IPO13 importin 13 0.652
CD27 CD27 molecule 0.646
TBK1 TANK-binding kinase 1 0.645
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 0.644
STAT1 signal transducer and activator of transcription 1, 91kDa 0.644
PGPEP1L pyroglutamyl-peptidase I-like 0.642
CRYBG1 crystallin beta-gamma domain containing 1 0.64
CD200 CD200 molecule 0.638
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.636
KMT5C lysine methyltransferase 5C 0.636
SHOC1 shortage in chiasmata 1 0.634
KRTAP4-8 keratin associated protein 4-8 0.633
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.633
KEAP1 kelch-like ECH-associated protein 1 0.63
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.63
NF2 neurofibromin 2 (merlin) 0.629
FOXG1 forkhead box G1 0.628
DCAF17 DDB1 and CUL4 associated factor 17 0.624
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.623
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.623
ZNF655 zinc finger protein 655 0.622
EXO5 exonuclease 5 0.622
SUGCT succinyl-CoA:glutarate-CoA transferase 0.621
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.621
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.62
OR52B2 olfactory receptor, family 52, subfamily B, member 2 0.62
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.619
CXCL13 chemokine (C-X-C motif) ligand 13 0.619
FECH ferrochelatase 0.618
STAG2 stromal antigen 2 0.618
GZMM granzyme M (lymphocyte met-ase 1) 0.615
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.614
CUL5 cullin 5 0.611
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.61
SPOP speckle-type POZ protein 0.609
PRMT5 protein arginine methyltransferase 5 0.609
MAK16 MAK16 homolog (S. cerevisiae) 0.609
HAUS6 HAUS augmin-like complex, subunit 6 0.608
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.608
STAG3 stromal antigen 3 0.607
DHFR2 dihydrofolate reductase 2 0.606
PTTG1 pituitary tumor-transforming 1 0.605
HIRA histone cell cycle regulator 0.604
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.604
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.603
GNPDA1 glucosamine-6-phosphate deaminase 1 0.603
KDM4D lysine (K)-specific demethylase 4D 0.602
METTL14 methyltransferase like 14 0.602
WRAP53 WD repeat containing, antisense to TP53 0.602
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.602
ACD adrenocortical dysplasia homolog (mouse) 0.6
UBE2B ubiquitin-conjugating enzyme E2B 0.6
CD44 CD44 molecule (Indian blood group) 0.6
CUL3 cullin 3 0.6
TASOR transcription activation suppressor 0.6
OR7E24 olfactory receptor, family 7, subfamily E, member 24 0.599
POTEC POTE ankyrin domain family, member C 0.599
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.599
CTAG1B cancer/testis antigen 1B 0.598
FLT1 fms-related tyrosine kinase 1 0.598
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.598
NUF2 NUF2, NDC80 kinetochore complex component 0.595
DBF4B DBF4 zinc finger B 0.595
ANXA6 annexin A6 0.595
PTCH1 patched 1 0.594
KDM1A lysine (K)-specific demethylase 1A 0.594
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.594
RUVBL1 RuvB-like AAA ATPase 1 0.594
PYDC1 PYD (pyrin domain) containing 1 0.594
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 0.593
E2F4 E2F transcription factor 4, p107/p130-binding 0.592
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.591
YTHDC2 YTH domain containing 2 0.591
FAM3D family with sequence similarity 3, member D 0.591
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.59
CLCF1 cardiotrophin-like cytokine factor 1 0.59
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.59
WT1 Wilms tumor 1 0.59
OR4C3 olfactory receptor, family 4, subfamily C, member 3 0.59
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.589
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 0.588
CRB2 crumbs family member 2 0.588
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.587
FMR1 fragile X mental retardation 1 0.586
LDHA lactate dehydrogenase A 0.586
IGF1R insulin-like growth factor 1 receptor 0.586
HSPA8 heat shock 70kDa protein 8 0.586
USP36 ubiquitin specific peptidase 36 0.585
EXOG endo/exonuclease (5'-3'), endonuclease G-like 0.585
GLI1 GLI family zinc finger 1 0.585
UBE2D1 ubiquitin-conjugating enzyme E2D 1 0.582
PTTG2 pituitary tumor-transforming 2 0.581
BCL2L1 BCL2-like 1 0.58
PRDM2 PR domain containing 2, with ZNF domain 0.58
CDC5L cell division cycle 5-like 0.579
SENP8 SUMO/sentrin specific peptidase family member 8 0.579
FUBP1 far upstream element (FUSE) binding protein 1 0.578
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.578
GTF2B general transcription factor IIB 0.578
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 0.577
IGSF11 immunoglobulin superfamily, member 11 0.577
APIP APAF1 interacting protein 0.577
ELOA elongin A 0.576
OR52I2 olfactory receptor, family 52, subfamily I, member 2 0.575
RBBP7 retinoblastoma binding protein 7 0.574
AGO4 argonaute RISC catalytic component 4 0.572
SOX9 SRY (sex determining region Y)-box 9 0.572
ZNF630 zinc finger protein 630 0.571
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.571
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.569
SNAI1 snail family zinc finger 1 0.569
SOX2 SRY (sex determining region Y)-box 2 0.568
NMT1 N-myristoyltransferase 1 0.567
RBMY1D RNA binding motif protein, Y-linked, family 1, member D 0.567
RSPO1 R-spondin 1 0.567
CHAF1B chromatin assembly factor 1, subunit B (p60) 0.566
CCL2 chemokine (C-C motif) ligand 2 0.566
TCF25 transcription factor 25 (basic helix-loop-helix) 0.566
SMAD3 SMAD family member 3 0.564
TERB2 telomere repeat binding bouquet formation protein 2 0.561
TOMM34 translocase of outer mitochondrial membrane 34 0.56
RNF111 ring finger protein 111 0.559
ADAR adenosine deaminase, RNA-specific 0.559
TMEM200B transmembrane protein 200B 0.558
ANAPC1 anaphase promoting complex subunit 1 0.558
IGFBP1 insulin-like growth factor binding protein 1 0.558
CCDC66 coiled-coil domain containing 66 0.558
CCNC cyclin C 0.557
KIF2C kinesin family member 2C 0.557
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.557
CHD1L chromodomain helicase DNA binding protein 1-like 0.556
TSC2 tuberous sclerosis 2 0.555
HBD hemoglobin, delta 0.555
ACIN1 apoptotic chromatin condensation inducer 1 0.554
CSNK1G1 casein kinase 1, gamma 1 0.553
NEK11 NIMA-related kinase 11 0.553
DDA1 DET1 and DDB1 associated 1 0.551
USP37 ubiquitin specific peptidase 37 0.55
FOXO3 forkhead box O3 0.55
DCAF1 DDB1 and CUL4 associated factor 1 0.549
MC3R melanocortin 3 receptor 0.548
CNOT4 CCR4-NOT transcription complex, subunit 4 0.547
EWSR1 EWS RNA-binding protein 1 0.547
BRWD3 bromodomain and WD repeat domain containing 3 0.547
PLEKHS1 pleckstrin homology domain containing, family S member 1 0.547
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.547
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.547
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.545
TBC1D12 TBC1 domain family, member 12 0.544
IL10 interleukin 10 0.543
ZNF605 zinc finger protein 605 0.542
VCF2 VCP nuclear cofactor family member 2 0.542
UBD ubiquitin D 0.541
ABRAXAS1 abraxas 1, BRCA1 A complex subunit 0.54
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 0.539
CCND2 cyclin D2 0.537