| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.142116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0956405 |
| LDHA | lactate dehydrogenase A | 0.0879712 |
| CSTB | cystatin B (stefin B) | 0.0773396 |
| CD44 | CD44 molecule (Indian blood group) | 0.076096 |
| DST | dystonin | 0.0730547 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0649391 |
| TPM3 | tropomyosin 3 | 0.0584654 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0554306 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0544289 |
| FLNB | filamin B, beta | 0.0504928 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0497965 |
| RUNX1 | runt-related transcription factor 1 | 0.0483609 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0433241 |
| HDAC9 | histone deacetylase 9 | 0.042635 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0402913 |
| CENPF | centromere protein F, 350/400kDa | 0.0396229 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.038198 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0378536 |
| MAP1B | microtubule-associated protein 1B | 0.0373458 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0372988 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0365864 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0346072 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0324942 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0323705 |
| SET | SET nuclear proto-oncogene | 0.0316535 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0310003 |
| APP | amyloid beta (A4) precursor protein | 0.0298212 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0297779 |
| MT2A | metallothionein 2A | 0.0296982 |
| NDRG1 | N-myc downstream regulated 1 | 0.0290546 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0288016 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0287947 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.028716 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0284566 |
| FBN1 | fibrillin 1 | 0.028014 |
| ENO1 | enolase 1, (alpha) | 0.0277761 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0277552 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0275005 |
| CANX | calnexin | 0.0268605 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0268518 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266947 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0258755 |
| SFTPA2 | surfactant protein A2 | 0.0254693 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254512 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0249794 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0249491 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0248785 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0246605 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0244784 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0243457 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.024229 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0240879 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0239745 |
| FNIP1 | folliculin interacting protein 1 | 0.0238399 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0238191 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0235511 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0232029 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0230672 |
| RND3 | Rho family GTPase 3 | 0.0227101 |
| LOC112694756 | uncharaterized LOC112694756 | 0.022663 |
| ARRDC3 | arrestin domain containing 3 | 0.0225583 |
| NAV2 | neuron navigator 2 | 0.0223156 |
| MKI67 | marker of proliferation Ki-67 | 0.0222138 |
| LOX | lysyl oxidase | 0.0220371 |
| MSN | moesin | 0.0218267 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.021738 |
| RTN4 | reticulon 4 | 0.021639 |
| ATP13A3 | ATPase type 13A3 | 0.0216287 |
| ZNF292 | zinc finger protein 292 | 0.0216207 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0214642 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0213802 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0213199 |
| ANXA5 | annexin A5 | 0.0210707 |
| DSPP | dentin sialophosphoprotein | 0.0210514 |
| ERBIN | erbb2 interacting protein | 0.021002 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0209312 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0208391 |
| ZNF148 | zinc finger protein 148 | 0.0207799 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0202989 |
| GLIS3 | GLIS family zinc finger 3 | 0.0200212 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0198213 |
| ANO6 | anoctamin 6 | 0.0194575 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0191368 |
| KIF5B | kinesin family member 5B | 0.0191024 |
| MB21D2 | Mab-21 domain containing 2 | 0.0190839 |
| RPS12 | ribosomal protein S12 | 0.0189176 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0187876 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0187774 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0187172 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0187125 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0185542 |
| OGA | O-GlcNAcase | 0.0182795 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0181327 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0181296 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0181114 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0181005 |
| MEF2A | myocyte enhancer factor 2A | 0.0179763 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.017892 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0178688 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.160011 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.13354 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133287 |
| TMSB10 | thymosin beta 10 | -0.11783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0902247 |
| PLAT | plasminogen activator, tissue | -0.0885646 |
| PTMA | prothymosin, alpha | -0.0875305 |
| HLA-B | major histocompatibility complex, class I, B | -0.0834918 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0812199 |
| LMNA | lamin A/C | -0.0651288 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0639631 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0597243 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0588871 |
| CAVIN1 | caveolae associated protein 1 | -0.0580317 |
| COL5A1 | collagen, type V, alpha 1 | -0.0553474 |
| S100A10 | S100 calcium binding protein A10 | -0.0521342 |
| CCND1 | cyclin D1 | -0.0453606 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0453071 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0421439 |
| HLA-C | major histocompatibility complex, class I, C | -0.0410181 |
| RPS24 | ribosomal protein S24 | -0.0363082 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.035734 |
| ACTG1 | actin gamma 1 | -0.0343957 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0338359 |
| AHNAK | AHNAK nucleoprotein | -0.0317287 |
| S100A6 | S100 calcium binding protein A6 | -0.0311267 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0296269 |
| KRT81 | keratin 81, type II | -0.0291851 |
| FN1 | fibronectin 1 | -0.0290381 |
| PRSS23 | protease, serine, 23 | -0.0289343 |
| CUX1 | cut-like homeobox 1 | -0.0276658 |
| MX2 | MX dynamin-like GTPase 2 | -0.0267195 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0261847 |
| CDH13 | cadherin 13 | -0.0254799 |
| RPL28 | ribosomal protein L28 | -0.0246022 |
| SUCNR1 | succinate receptor 1 | -0.0243789 |
| RPS15 | ribosomal protein S15 | -0.0240478 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0233458 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0230331 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0228999 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0225 |
| NAV1 | neuron navigator 1 | -0.0222036 |
| COL1A1 | collagen, type I, alpha 1 | -0.0220121 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0218757 |
| RRBP1 | ribosome binding protein 1 | -0.0218419 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0217761 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0210947 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0209538 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0205687 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0204527 |
| RPLP2 | ribosomal protein, large, P2 | -0.0204332 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0201577 |
| RPL35A | ribosomal protein L35a | -0.0197543 |
| RPL38 | ribosomal protein L38 | -0.0196564 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0196497 |
| LRRC17 | leucine rich repeat containing 17 | -0.0194838 |
| RPS6 | ribosomal protein S6 | -0.0192972 |
| CD99 | CD99 molecule | -0.0190882 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0186155 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0184426 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.01809 |
| FTL | ferritin, light polypeptide | -0.0179771 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0178398 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0175515 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0175349 |
| MTDH | metadherin | -0.0174924 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0174806 |
| THY1 | Thy-1 cell surface antigen | -0.0174609 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0174492 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0171106 |
| SLC38A1 | solute carrier family 38, member 1 | -0.017105 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0170293 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0170119 |
| CD81 | CD81 molecule | -0.0166632 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0164668 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0164174 |
| INTS6 | integrator complex subunit 6 | -0.0162654 |
| SEC61G | Sec61 gamma subunit | -0.0162214 |
| MAP4 | microtubule-associated protein 4 | -0.0160151 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0159256 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0159032 |
| THBS2 | thrombospondin 2 | -0.0158942 |
| CYTH3 | cytohesin 3 | -0.0158374 |
| RPS11 | ribosomal protein S11 | -0.0156674 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0156089 |
| RPS23 | ribosomal protein S23 | -0.0155377 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0153938 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0153168 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0152129 |
| SERF2 | small EDRK-rich factor 2 | -0.0150347 |
| H3-3B | H3.3 histone B | -0.0148693 |
| RPS21 | ribosomal protein S21 | -0.0148083 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0146432 |
| CTSD | cathepsin D | -0.0144666 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0143742 |
| IL7R | interleukin 7 receptor | -0.0143366 |
| DCLK2 | doublecortin-like kinase 2 | -0.0140457 |
| HM13 | histocompatibility (minor) 13 | -0.0138718 |
| TNS3 | tensin 3 | -0.0138043 |
| IER3 | immediate early response 3 | -0.013351 |
