| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.22313 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.136629 |
| LAMB3 | laminin, beta 3 | 0.127435 |
| MCL1 | myeloid cell leukemia 1 | 0.122709 |
| EFNA5 | ephrin-A5 | 0.114939 |
| EGFR | epidermal growth factor receptor | 0.1132 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.109451 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.109085 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.106906 |
| FLNB | filamin B, beta | 0.100281 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0965202 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.086838 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0842855 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.082486 |
| TPM3 | tropomyosin 3 | 0.0807195 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0802167 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0752219 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0746264 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0720821 |
| TRRAP | transformation/transcription domain-associated protein | 0.0716698 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0699848 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0695304 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0689764 |
| DSPP | dentin sialophosphoprotein | 0.0676507 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0659964 |
| FMNL2 | formin-like 2 | 0.0652743 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.06195 |
| LDHA | lactate dehydrogenase A | 0.0612545 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0593352 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0575834 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0559841 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0542386 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0535659 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0534096 |
| RPS12 | ribosomal protein S12 | 0.0523576 |
| PGK1 | phosphoglycerate kinase 1 | 0.0523033 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0521783 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0507921 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0507907 |
| ENO1 | enolase 1, (alpha) | 0.0492708 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0491475 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0467015 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0461831 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0461546 |
| MXD1 | MAX dimerization protein 1 | 0.0460715 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0457223 |
| DIAPH1 | diaphanous-related formin 1 | 0.0452435 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0451213 |
| SMAD3 | SMAD family member 3 | 0.0449654 |
| EZR | ezrin | 0.0448191 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0447275 |
| TGM2 | transglutaminase 2 | 0.0444607 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.042539 |
| BMP6 | bone morphogenetic protein 6 | 0.0424454 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.041107 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0408707 |
| HMGA2 | high mobility group AT-hook 2 | 0.0406412 |
| TLN1 | talin 1 | 0.0404897 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0403508 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0402853 |
| LAMC2 | laminin, gamma 2 | 0.0401358 |
| SGMS2 | sphingomyelin synthase 2 | 0.039854 |
| CLMP | CXADR-like membrane protein | 0.0394689 |
| MSN | moesin | 0.0394138 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0389332 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0384269 |
| FAM107B | family with sequence similarity 107, member B | 0.037466 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0371746 |
| GOLGB1 | golgin B1 | 0.0363179 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0362909 |
| SP100 | SP100 nuclear antigen | 0.0361565 |
| PLEC | plectin | 0.0361243 |
| B2M | beta-2-microglobulin | 0.0361096 |
| RIOK3 | RIO kinase 3 | 0.0359638 |
| PMM2 | phosphomannomutase 2 | 0.0353536 |
| SET | SET nuclear proto-oncogene | 0.0352702 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0351482 |
| EFNB2 | ephrin-B2 | 0.0345845 |
| VIM | vimentin | 0.0339377 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0339142 |
| RPL37A | ribosomal protein L37a | 0.0338563 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0334854 |
| FTL | ferritin, light polypeptide | 0.0333288 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0333274 |
| INTS6 | integrator complex subunit 6 | 0.033288 |
| CD44 | CD44 molecule (Indian blood group) | 0.0332425 |
| PARD3 | par-3 family cell polarity regulator | 0.0331676 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0331154 |
| MMP1 | matrix metallopeptidase 1 | 0.0330406 |
| TXNRD1 | thioredoxin reductase 1 | 0.0326714 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0323836 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0323451 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0322392 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0321874 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320349 |
| SFTPA2 | surfactant protein A2 | 0.0320018 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0315699 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0315303 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0310722 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0306589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0790758 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0734077 |
| PTMA | prothymosin, alpha | -0.0716932 |
| LMO7 | LIM domain 7 | -0.0683399 |
| TMSB10 | thymosin beta 10 | -0.0635716 |
| S100A4 | S100 calcium binding protein A4 | -0.0552984 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0497464 |
| POTEF | POTE ankyrin domain family, member F | -0.0497259 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0482127 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0472966 |
| MUC17 | mucin 17, cell surface associated | -0.0450492 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0432621 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0428536 |
| ACTG1 | actin gamma 1 | -0.0423923 |
| CD2AP | CD2-associated protein | -0.0384193 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0378265 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0375748 |
| PERP | PERP, TP53 apoptosis effector | -0.0355456 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0313581 |
| RTN4 | reticulon 4 | -0.029328 |
| AHNAK | AHNAK nucleoprotein | -0.0288775 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0277322 |
| MYOF | myoferlin | -0.0276323 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.02688 |
| S100A10 | S100 calcium binding protein A10 | -0.026681 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0265762 |
| NEK7 | NIMA-related kinase 7 | -0.0259476 |
| VCL | vinculin | -0.025946 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0255168 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0254204 |
| ANLN | anillin, actin binding protein | -0.0250724 |
| PRSS3 | protease, serine, 3 | -0.0248665 |
| WASF2 | WAS protein family, member 2 | -0.0240815 |
| ITGB4 | integrin, beta 4 | -0.024036 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0236225 |
| FOSL1 | FOS-like antigen 1 | -0.0231874 |
| MIDN | midnolin | -0.0230048 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0228064 |
| NCOA3 | nuclear receptor coactivator 3 | -0.022341 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0219469 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0215452 |
| RPS21 | ribosomal protein S21 | -0.0214432 |
| SQSTM1 | sequestosome 1 | -0.02126 |
| NPSR1 | neuropeptide S receptor 1 | -0.0211814 |
| THOC2 | THO complex 2 | -0.0210142 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0208989 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0206342 |
| EMP1 | epithelial membrane protein 1 | -0.0206129 |
| RPS24 | ribosomal protein S24 | -0.0203632 |
| GNAS | GNAS complex locus | -0.0202872 |
| TOP1 | topoisomerase (DNA) I | -0.0202246 |
| ETNK1 | ethanolamine kinase 1 | -0.0202166 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0201831 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0200418 |
| PLAT | plasminogen activator, tissue | -0.019793 |
| TMEM263 | transmembrane protein 263 | -0.0196264 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.019383 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0193373 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0193105 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.019149 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0191361 |
| KRT8 | keratin 8, type II | -0.0189139 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0182954 |
| RRBP1 | ribosome binding protein 1 | -0.0181601 |
| IRF1 | interferon regulatory factor 1 | -0.0181392 |
| ZNF292 | zinc finger protein 292 | -0.0180711 |
| IER3 | immediate early response 3 | -0.0180612 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0179423 |
| DSG2 | desmoglein 2 | -0.0178148 |
| RPL34 | ribosomal protein L34 | -0.0178026 |
| RBM25 | RNA binding motif protein 25 | -0.0177933 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0177095 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0176582 |
| PLAC8 | placenta-specific 8 | -0.0174667 |
| LYZ | lysozyme | -0.0173098 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0171557 |
| TJP2 | tight junction protein 2 | -0.0168875 |
| VCAN | versican | -0.0168664 |
| MCU | mitochondrial calcium uniporter | -0.0168575 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0166212 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0165816 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0164304 |
| TSPAN3 | tetraspanin 3 | -0.0163193 |
| MYO6 | myosin VI | -0.016016 |
| RPS23 | ribosomal protein S23 | -0.0159775 |
| JUP | junction plakoglobin | -0.0159313 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0158217 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0156777 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0156611 |
| PON2 | paraoxonase 2 | -0.0156532 |
| OXR1 | oxidation resistance 1 | -0.0156202 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0156201 |
| ANXA11 | annexin A11 | -0.0155486 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0154669 |
| RHEB | Ras homolog enriched in brain | -0.0154073 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.015259 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0151804 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0149569 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0149011 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0148942 |
