| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.0866271 |
| LAMB3 | laminin, beta 3 | 0.0865918 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0780672 |
| MCL1 | myeloid cell leukemia 1 | 0.0636647 |
| ENO1 | enolase 1, (alpha) | 0.061093 |
| CP | ceruloplasmin (ferroxidase) | 0.0589505 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0547925 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0543005 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0521006 |
| LDHA | lactate dehydrogenase A | 0.0516312 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491699 |
| NDRG1 | N-myc downstream regulated 1 | 0.0488072 |
| FAM107B | family with sequence similarity 107, member B | 0.0470245 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0459581 |
| CFB | complement factor B | 0.045432 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0444658 |
| B2M | beta-2-microglobulin | 0.0441091 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0436036 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0434682 |
| RPL37A | ribosomal protein L37a | 0.0412794 |
| RPS12 | ribosomal protein S12 | 0.0410301 |
| DTNA | dystrobrevin, alpha | 0.0409959 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0404988 |
| CSTB | cystatin B (stefin B) | 0.0398547 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0387104 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0371192 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0367836 |
| EGR1 | early growth response 1 | 0.0361758 |
| LAMC2 | laminin, gamma 2 | 0.0361285 |
| GOLGB1 | golgin B1 | 0.0341445 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0337008 |
| RPL35A | ribosomal protein L35a | 0.0321432 |
| SP100 | SP100 nuclear antigen | 0.0319592 |
| SFTPA2 | surfactant protein A2 | 0.0312684 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310529 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.03102 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0307709 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0301201 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0291388 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0288855 |
| EGFR | epidermal growth factor receptor | 0.0286669 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0285754 |
| SGMS2 | sphingomyelin synthase 2 | 0.0285737 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0285226 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0284563 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0281361 |
| EFNA5 | ephrin-A5 | 0.0280127 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0276731 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0270209 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0268872 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0268235 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0266185 |
| INTS6 | integrator complex subunit 6 | 0.0263328 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0259157 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0258406 |
| LCN2 | lipocalin 2 | 0.0257973 |
| NRG3 | neuregulin 3 | 0.0257931 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0256134 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0255757 |
| HDAC9 | histone deacetylase 9 | 0.025424 |
| DSPP | dentin sialophosphoprotein | 0.0252449 |
| RPS8 | ribosomal protein S8 | 0.0252019 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0249489 |
| SMAD3 | SMAD family member 3 | 0.0244252 |
| RPS3 | ribosomal protein S3 | 0.0242513 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.024219 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0240411 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0240211 |
| ASPH | aspartate beta-hydroxylase | 0.0238752 |
| KYNU | kynureninase | 0.0237024 |
| GRB10 | growth factor receptor-bound protein 10 | 0.023691 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.022566 |
| SQSTM1 | sequestosome 1 | 0.0223809 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0223647 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0222305 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0222007 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0221556 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0221171 |
| PHF3 | PHD finger protein 3 | 0.0218809 |
| HKDC1 | hexokinase domain containing 1 | 0.0216302 |
| NABP1 | nucleic acid binding protein 1 | 0.0215647 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0214585 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0212973 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.021296 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0211098 |
| HLA-A | major histocompatibility complex, class I, A | 0.0210478 |
| JUN | jun proto-oncogene | 0.0210316 |
| RPS17 | ribosomal protein S17 | 0.0210162 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0208155 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0206575 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0204813 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0201789 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0201321 |
| RPL23 | ribosomal protein L23 | 0.0199518 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0198269 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0196353 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0195403 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0192843 |
| RACK1 | receptor for activated C kinase 1 | 0.0191489 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.019134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128891 |
| MT1X | metallothionein 1X | -0.0894712 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0880709 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0533654 |
| TMSB10 | thymosin beta 10 | -0.0518479 |
| AHNAK | AHNAK nucleoprotein | -0.0485129 |
| PTMA | prothymosin, alpha | -0.0460986 |
| MT2A | metallothionein 2A | -0.0456184 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438947 |
| MMP7 | matrix metallopeptidase 7 | -0.0419962 |
| POTEF | POTE ankyrin domain family, member F | -0.0417258 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0412541 |
| ACTG1 | actin gamma 1 | -0.0366648 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.032842 |
| CD2AP | CD2-associated protein | -0.0326497 |
| RTN4 | reticulon 4 | -0.0317847 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0315326 |
| WDR45B | WD repeat domain 45B | -0.0302622 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0290757 |
| PLAUR | plasminogen activator, urokinase receptor | -0.027451 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0261271 |
| FTL | ferritin, light polypeptide | -0.0246774 |
| FAM162A | family with sequence similarity 162, member A | -0.023855 |
| RPS21 | ribosomal protein S21 | -0.0234825 |
| MYOF | myoferlin | -0.0230089 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0228791 |
| JUP | junction plakoglobin | -0.022427 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0219506 |
| CDCP1 | CUB domain containing protein 1 | -0.0216395 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0212374 |
| DSG2 | desmoglein 2 | -0.0208532 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.020609 |
| PFKP | phosphofructokinase, platelet | -0.0200451 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0199627 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0197985 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0197663 |
| RRBP1 | ribosome binding protein 1 | -0.0190935 |
| MACC1 | metastasis associated in colon cancer 1 | -0.019085 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0190308 |
| CD47 | CD47 molecule | -0.0189655 |
| RNF149 | ring finger protein 149 | -0.0189046 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0188612 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0187041 |
| ZNF292 | zinc finger protein 292 | -0.0185572 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0183799 |
| NCKAP5 | NCK-associated protein 5 | -0.0179516 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0177283 |
| MAP1B | microtubule-associated protein 1B | -0.0176744 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0175522 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0175026 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0174942 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0174611 |
| RPS23 | ribosomal protein S23 | -0.0172845 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0172104 |
| RBM39 | RNA binding motif protein 39 | -0.0171598 |
| CCNI | cyclin I | -0.0170192 |
| ACTN4 | actinin, alpha 4 | -0.0169785 |
| LMNA | lamin A/C | -0.0169334 |
| ITGA6 | integrin, alpha 6 | -0.0169142 |
| UBC | ubiquitin C | -0.0165422 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0163162 |
| RBM25 | RNA binding motif protein 25 | -0.0162211 |
| DEK | DEK proto-oncogene | -0.0160722 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0159903 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0157201 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.015575 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0154992 |
| TAPBP | TAP binding protein (tapasin) | -0.0153488 |
| H1-0 | H1.0 linker histone | -0.0152715 |
| EMP1 | epithelial membrane protein 1 | -0.0152555 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0152532 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.015203 |
| S100A6 | S100 calcium binding protein A6 | -0.015086 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0149652 |
| NRP1 | neuropilin 1 | -0.0148738 |
| BCL2L1 | BCL2-like 1 | -0.0148557 |
| PLAU | plasminogen activator, urokinase | -0.0148553 |
| CCNL1 | cyclin L1 | -0.0147986 |
| TUBB | tubulin, beta class I | -0.0147968 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0147893 |
| ABI1 | abl-interactor 1 | -0.0147752 |
| INSIG1 | insulin induced gene 1 | -0.0147415 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0145232 |
| OSMR | oncostatin M receptor | -0.014507 |
| RLF | rearranged L-myc fusion | -0.014482 |
| RASA2 | RAS p21 protein activator 2 | -0.0144371 |
| FERMT1 | fermitin family member 1 | -0.0144269 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0143516 |
| EHBP1 | EH domain binding protein 1 | -0.0143054 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0142872 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0141675 |
| CSNK1E | casein kinase 1, epsilon | -0.0141218 |
| ZNF654 | zinc finger protein 654 | -0.0140203 |
| FOSL1 | FOS-like antigen 1 | -0.013986 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0139717 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0139072 |
| PRR11 | proline rich 11 | -0.0137422 |
| SVIL | supervillin | -0.0136856 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.013681 |
| DIAPH1 | diaphanous-related formin 1 | -0.0136147 |
