| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.194084 |
| B2M | beta-2-microglobulin | 0.162946 |
| LMO7 | LIM domain 7 | 0.110726 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0974794 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0974488 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0935631 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0872064 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0826182 |
| ENO1 | enolase 1, (alpha) | 0.082262 |
| MYO1E | myosin IE | 0.0771379 |
| LDHA | lactate dehydrogenase A | 0.0762826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0733104 |
| SMAD3 | SMAD family member 3 | 0.0718487 |
| FTL | ferritin, light polypeptide | 0.0706821 |
| RUNX1 | runt-related transcription factor 1 | 0.0705979 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0688261 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0602853 |
| EPHB2 | EPH receptor B2 | 0.0602593 |
| DSPP | dentin sialophosphoprotein | 0.0588967 |
| CALR | calreticulin | 0.0564537 |
| RPL23 | ribosomal protein L23 | 0.0563668 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0562217 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0561417 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0559385 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0554348 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0526539 |
| SFTPA2 | surfactant protein A2 | 0.0520858 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0500887 |
| SET | SET nuclear proto-oncogene | 0.0498966 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0495085 |
| EREG | epiregulin | 0.048229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0472602 |
| RPL35A | ribosomal protein L35a | 0.0469805 |
| NDRG1 | N-myc downstream regulated 1 | 0.0464402 |
| RND3 | Rho family GTPase 3 | 0.045297 |
| DST | dystonin | 0.0448004 |
| RPS12 | ribosomal protein S12 | 0.0446717 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.044581 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0445593 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0442149 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0423002 |
| MT2A | metallothionein 2A | 0.0422773 |
| KYNU | kynureninase | 0.0421214 |
| PDZD8 | PDZ domain containing 8 | 0.0419448 |
| HKDC1 | hexokinase domain containing 1 | 0.04138 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0409576 |
| CSTB | cystatin B (stefin B) | 0.040833 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0393653 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0379096 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0377656 |
| TMSB10 | thymosin beta 10 | 0.037169 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0367794 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0358752 |
| RPS8 | ribosomal protein S8 | 0.035681 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0354967 |
| RPS3 | ribosomal protein S3 | 0.03477 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0345479 |
| RPL11 | ribosomal protein L11 | 0.0343522 |
| ASPH | aspartate beta-hydroxylase | 0.0326712 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0324974 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0323091 |
| RPL26 | ribosomal protein L26 | 0.0321069 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320773 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0316677 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0315329 |
| CD46 | CD46 molecule, complement regulatory protein | 0.030964 |
| RPL30 | ribosomal protein L30 | 0.030312 |
| RPL37A | ribosomal protein L37a | 0.0301741 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.029968 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0299663 |
| EPCAM | epithelial cell adhesion molecule | 0.0299551 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0299213 |
| MUC13 | mucin 13, cell surface associated | 0.0297224 |
| TRIM2 | tripartite motif containing 2 | 0.0292166 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0290605 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0290114 |
| TPM3 | tropomyosin 3 | 0.0289746 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0289686 |
| FAT1 | FAT atypical cadherin 1 | 0.0289123 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0287837 |
| MCL1 | myeloid cell leukemia 1 | 0.0287304 |
| ITM2B | integral membrane protein 2B | 0.02864 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0280173 |
| CDHR2 | cadherin-related family member 2 | 0.0279831 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0278243 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0276655 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0274481 |
| PCBP2 | poly(rC) binding protein 2 | 0.0273848 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.027072 |
| RACK1 | receptor for activated C kinase 1 | 0.0269792 |
| DUSP16 | dual specificity phosphatase 16 | 0.0268362 |
| TXNRD1 | thioredoxin reductase 1 | 0.0264934 |
| ANXA1 | annexin A1 | 0.0263809 |
| RPL7 | ribosomal protein L7 | 0.0263036 |
| MYO5B | myosin VB | 0.0262065 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0260303 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0257238 |
| RPS17 | ribosomal protein S17 | 0.0257082 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0256945 |
| YAP1 | Yes-associated protein 1 | 0.0254737 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XAF1 | XIAP associated factor 1 | -0.11535 |
| LYZ | lysozyme | -0.115162 |
| RNF213 | ring finger protein 213 | -0.113168 |
| NPSR1 | neuropeptide S receptor 1 | -0.11169 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.104976 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.104345 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.100639 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0864047 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0834819 |
| RIGI | RNA sensor RIG-I | -0.0795409 |
| PLSCR2 | phospholipid scramblase 2 | -0.0784523 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0738201 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0693779 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.06868 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0676063 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0674672 |
| SP100 | SP100 nuclear antigen | -0.0669824 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0669644 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0639326 |
| ANXA2 | annexin A2 | -0.0628808 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0623854 |
| TXNIP | thioredoxin interacting protein | -0.0622493 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0613914 |
| PLSCR1 | phospholipid scramblase 1 | -0.0600469 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0594518 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0575648 |
| PRKCA | protein kinase C, alpha | -0.0574487 |
| WDR45B | WD repeat domain 45B | -0.0540472 |
| MUC20 | mucin 20, cell surface associated | -0.0513054 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0496545 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0486481 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0469905 |
| SSH2 | slingshot protein phosphatase 2 | -0.0466367 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0464494 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0445456 |
| APOL1 | apolipoprotein L, 1 | -0.0438049 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0432476 |
| PHF3 | PHD finger protein 3 | -0.0432446 |
| POF1B | premature ovarian failure, 1B | -0.0423598 |
| VCL | vinculin | -0.0423383 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0421272 |
| INTS6 | integrator complex subunit 6 | -0.041784 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0404929 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0403301 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0387525 |
| PMP22 | peripheral myelin protein 22 | -0.0383879 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0376692 |
| MX2 | MX dynamin-like GTPase 2 | -0.0373095 |
| PTMA | prothymosin, alpha | -0.0370047 |
| APOL6 | apolipoprotein L, 6 | -0.0367709 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0367246 |
| H1-0 | H1.0 linker histone | -0.0363453 |
| POU2F2 | POU class 2 homeobox 2 | -0.0354363 |
| TNS4 | tensin 4 | -0.0352567 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0346394 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0344997 |
| HLA-B | major histocompatibility complex, class I, B | -0.0343266 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0341289 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.033826 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0336583 |
| AHNAK | AHNAK nucleoprotein | -0.0333784 |
| ACTG1 | actin gamma 1 | -0.0329304 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.032799 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0325022 |
| CTSD | cathepsin D | -0.0319785 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0317834 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0314724 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.031354 |
| HLA-C | major histocompatibility complex, class I, C | -0.0310697 |
| MAP7 | microtubule-associated protein 7 | -0.0296431 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0294962 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0294145 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0292881 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0286588 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0284975 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0284665 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0283469 |
| EGR1 | early growth response 1 | -0.0283419 |
| NF1 | neurofibromin 1 | -0.0283337 |
| ABLIM1 | actin binding LIM protein 1 | -0.0282904 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0280699 |
| TFRC | transferrin receptor | -0.0277695 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0274986 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0273901 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0273548 |
| WASF2 | WAS protein family, member 2 | -0.0270204 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0268682 |
| NABP1 | nucleic acid binding protein 1 | -0.0268521 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0268233 |
| EZR | ezrin | -0.026263 |
| TRIM56 | tripartite motif containing 56 | -0.0261564 |
| ARHGAP27 | Rho GTPase activating protein 27 | -0.0256221 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0255975 |
| MX1 | MX dynamin-like GTPase 1 | -0.0253918 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0251673 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0249633 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0248789 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0247126 |
| FOXO3 | forkhead box O3 | -0.0246738 |
| VMP1 | vacuole membrane protein 1 | -0.0245735 |
