| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.362043 |
| LDHA | lactate dehydrogenase A | 0.178198 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.14977 |
| ASPH | aspartate beta-hydroxylase | 0.0963857 |
| ENO1 | enolase 1, (alpha) | 0.091687 |
| MKI67 | marker of proliferation Ki-67 | 0.0861441 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0828286 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0790877 |
| CD44 | CD44 molecule (Indian blood group) | 0.0690673 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0666167 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.066517 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0645075 |
| CANX | calnexin | 0.0642436 |
| CENPF | centromere protein F, 350/400kDa | 0.0632424 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0606736 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0582085 |
| CALR | calreticulin | 0.0576621 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0520203 |
| KYNU | kynureninase | 0.0516169 |
| DST | dystonin | 0.0511914 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0501839 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0485416 |
| ANLN | anillin, actin binding protein | 0.048238 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0479464 |
| SMAD3 | SMAD family member 3 | 0.0444526 |
| PGK1 | phosphoglycerate kinase 1 | 0.0439635 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0438404 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0434929 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0416103 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.041458 |
| TXNRD1 | thioredoxin reductase 1 | 0.0406407 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0398033 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0397318 |
| APP | amyloid beta (A4) precursor protein | 0.0386091 |
| SQSTM1 | sequestosome 1 | 0.0382198 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.038102 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0379328 |
| MAP1B | microtubule-associated protein 1B | 0.0378147 |
| B2M | beta-2-microglobulin | 0.0369681 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.036836 |
| SFTPA2 | surfactant protein A2 | 0.0367396 |
| SET | SET nuclear proto-oncogene | 0.0354961 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0343921 |
| IL6ST | interleukin 6 signal transducer | 0.0332148 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330181 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0327085 |
| VCL | vinculin | 0.0321265 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0321129 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0318101 |
| STC1 | stanniocalcin 1 | 0.0309825 |
| YBX1 | Y box binding protein 1 | 0.0308428 |
| NAV2 | neuron navigator 2 | 0.0307954 |
| RPL23 | ribosomal protein L23 | 0.0305527 |
| PTK2 | protein tyrosine kinase 2 | 0.0303357 |
| TPI1 | triosephosphate isomerase 1 | 0.0299534 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0299397 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0297469 |
| ATP13A3 | ATPase type 13A3 | 0.0295888 |
| TPM3 | tropomyosin 3 | 0.0292263 |
| ACTN4 | actinin, alpha 4 | 0.0289624 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.028939 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0283289 |
| RPL7 | ribosomal protein L7 | 0.0283021 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0282451 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0282399 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0278143 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0277452 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0267915 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0266031 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0262291 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0261145 |
| PCBP2 | poly(rC) binding protein 2 | 0.0258022 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0256185 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0255452 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253813 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0253403 |
| GPC6 | glypican 6 | 0.0248464 |
| PRELID2 | PRELI domain containing 2 | 0.0248034 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0247101 |
| PKM | pyruvate kinase, muscle | 0.0246471 |
| NDRG1 | N-myc downstream regulated 1 | 0.0246401 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0243263 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0241137 |
| RPL3 | ribosomal protein L3 | 0.0239443 |
| GLIS3 | GLIS family zinc finger 3 | 0.0231213 |
| TPR | translocated promoter region, nuclear basket protein | 0.0231097 |
| WWOX | WW domain containing oxidoreductase | 0.0230956 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0229064 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0227783 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0222732 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0219865 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.021844 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0216485 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0216038 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0215299 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0215216 |
| SCRN1 | secernin 1 | 0.021477 |
| WBP11 | WW domain binding protein 11 | 0.02142 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.021297 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0211596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.280235 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.277741 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.108895 |
| TMSB10 | thymosin beta 10 | -0.0891595 |
| FN1 | fibronectin 1 | -0.0888626 |
| MT2A | metallothionein 2A | -0.0777374 |
| FTL | ferritin, light polypeptide | -0.0621463 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.061618 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0615595 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0488306 |
| HLA-B | major histocompatibility complex, class I, B | -0.0484827 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0458951 |
| EGFR | epidermal growth factor receptor | -0.0429608 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0427882 |
| RPL28 | ribosomal protein L28 | -0.041733 |
| VIM | vimentin | -0.039826 |
| DTNA | dystrobrevin, alpha | -0.0372353 |
| CLMP | CXADR-like membrane protein | -0.0345031 |
| MT1X | metallothionein 1X | -0.0339845 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0334355 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0331864 |
| POTEF | POTE ankyrin domain family, member F | -0.031424 |
| RPS6 | ribosomal protein S6 | -0.0313029 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0298331 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0287338 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0282902 |
| MMP12 | matrix metallopeptidase 12 | -0.0279299 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0278601 |
| RPS23 | ribosomal protein S23 | -0.0270032 |
| TENM3 | teneurin transmembrane protein 3 | -0.0264763 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0263255 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0254268 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0252599 |
| PTCHD4 | patched domain containing 4 | -0.0252551 |
| HIP1 | huntingtin interacting protein 1 | -0.0241719 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.02407 |
| RPS24 | ribosomal protein S24 | -0.0236683 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0235606 |
| SEC61G | Sec61 gamma subunit | -0.0232406 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0231352 |
| HDAC9 | histone deacetylase 9 | -0.0228596 |
| NAV1 | neuron navigator 1 | -0.021177 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0211066 |
| NAV3 | neuron navigator 3 | -0.0211018 |
| EMP1 | epithelial membrane protein 1 | -0.0211003 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0203674 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0203366 |
| COPA | coatomer protein complex, subunit alpha | -0.020175 |
| CALD1 | caldesmon 1 | -0.0200464 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0200125 |
| VEGFA | vascular endothelial growth factor A | -0.0198045 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0195945 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.019547 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0194083 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0193328 |
| CFAP96 | cilia and flagella associated protein 96 | -0.0191594 |
| SEC24D | SEC24 family member D | -0.0191478 |
| CCND1 | cyclin D1 | -0.0191152 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0190505 |
| PXDN | peroxidasin | -0.0187746 |
| MYADM | myeloid-associated differentiation marker | -0.0181075 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0180583 |
| NABP1 | nucleic acid binding protein 1 | -0.0174948 |
| NBEAL1 | neurobeachin-like 1 | -0.0173914 |
| RPLP1 | ribosomal protein, large, P1 | -0.0173318 |
| OXR1 | oxidation resistance 1 | -0.0172937 |
| S100A6 | S100 calcium binding protein A6 | -0.0171602 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0170592 |
| CCNI | cyclin I | -0.0166771 |
| WDR45B | WD repeat domain 45B | -0.0166691 |
| RPS5 | ribosomal protein S5 | -0.0165915 |
| FBXO34 | F-box protein 34 | -0.016585 |
| RPS13 | ribosomal protein S13 | -0.0164913 |
| RPL37A | ribosomal protein L37a | -0.0164227 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0164018 |
| TMEM263 | transmembrane protein 263 | -0.0163114 |
| RPL27A | ribosomal protein L27a | -0.0162026 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0160903 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.0157917 |
| GPR173 | G protein-coupled receptor 173 | -0.0157458 |
| GNAS | GNAS complex locus | -0.0156812 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0155947 |
| RPLP2 | ribosomal protein, large, P2 | -0.0155448 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0155273 |
| TPM4 | tropomyosin 4 | -0.0152461 |
| FANK1 | fibronectin type III and ankyrin repeat domains 1 | -0.015231 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0152181 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0149821 |
| ASTN2 | astrotactin 2 | -0.0148642 |
| PCNX4 | pecanex 4 | -0.014832 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0147021 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.014621 |
| TTYH3 | tweety family member 3 | -0.0146099 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0146002 |
| CDK6 | cyclin-dependent kinase 6 | -0.0144661 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0144172 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0143601 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0143446 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0143409 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0143098 |
