| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.247142 |
| ENO1 | enolase 1, (alpha) | 0.174995 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1699 |
| FAT1 | FAT atypical cadherin 1 | 0.157368 |
| LDHA | lactate dehydrogenase A | 0.147732 |
| NDRG1 | N-myc downstream regulated 1 | 0.106477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.098239 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0972419 |
| KRT18 | keratin 18, type I | 0.09084 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.087886 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0744607 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0683105 |
| EPCAM | epithelial cell adhesion molecule | 0.0663456 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0645861 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0635702 |
| TPM3 | tropomyosin 3 | 0.0598965 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0572499 |
| SET | SET nuclear proto-oncogene | 0.0555022 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0527143 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0521552 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0517698 |
| PGK1 | phosphoglycerate kinase 1 | 0.051095 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0506563 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0493912 |
| KRT8 | keratin 8, type II | 0.0488683 |
| MT2A | metallothionein 2A | 0.043918 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0438122 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0431611 |
| SFTPA2 | surfactant protein A2 | 0.0426099 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0409456 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0403917 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0403473 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0398773 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0397088 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0396223 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0387609 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0382794 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0375125 |
| CANX | calnexin | 0.0374112 |
| CALR | calreticulin | 0.0370137 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0368534 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0366617 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0360196 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0358903 |
| INTS6 | integrator complex subunit 6 | 0.0358891 |
| EZR | ezrin | 0.0355865 |
| KIF5B | kinesin family member 5B | 0.0347978 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.034304 |
| TENM3 | teneurin transmembrane protein 3 | 0.033134 |
| TPI1 | triosephosphate isomerase 1 | 0.0327786 |
| MKI67 | marker of proliferation Ki-67 | 0.0327203 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0324424 |
| DST | dystonin | 0.0319298 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0309983 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.030922 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0297177 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0295977 |
| JUN | jun proto-oncogene | 0.0295772 |
| IPO7 | importin 7 | 0.0293188 |
| ARRDC3 | arrestin domain containing 3 | 0.0291863 |
| RPL3 | ribosomal protein L3 | 0.0289967 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0286476 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0286331 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0281407 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0281366 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0279446 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0277629 |
| CNN3 | calponin 3, acidic | 0.0272654 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0272235 |
| MLEC | malectin | 0.0271008 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0268815 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.026789 |
| LRRC23 | leucine rich repeat containing 23 | 0.0261566 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.025015 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0246171 |
| RRM2 | ribonucleotide reductase M2 | 0.0245194 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0236062 |
| RACK1 | receptor for activated C kinase 1 | 0.0235437 |
| MCL1 | myeloid cell leukemia 1 | 0.0234947 |
| ANXA2 | annexin A2 | 0.0234675 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0233589 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0233373 |
| PLEC | plectin | 0.023245 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0226942 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0226668 |
| FLNB | filamin B, beta | 0.0226068 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.0225865 |
| FN1 | fibronectin 1 | 0.0223988 |
| SVIL | supervillin | 0.0221811 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.022168 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0219695 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0219655 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.021965 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0215763 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0212999 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0210796 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0210569 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0209105 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.020797 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.020762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281574 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106402 |
| RPS6 | ribosomal protein S6 | -0.101013 |
| PTMA | prothymosin, alpha | -0.0921522 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0905025 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0855356 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0632095 |
| GOLGA4 | golgin A4 | -0.0588307 |
| SETD5 | SET domain containing 5 | -0.0574287 |
| ARF4 | ADP-ribosylation factor 4 | -0.0543164 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0525057 |
| NF1 | neurofibromin 1 | -0.0524239 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0511746 |
| RPS24 | ribosomal protein S24 | -0.0491567 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0488734 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0483042 |
| RPLP2 | ribosomal protein, large, P2 | -0.0473649 |
| AHNAK | AHNAK nucleoprotein | -0.0468495 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0458536 |
| RAD51B | RAD51 paralog B | -0.044778 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0445952 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438613 |
| GLG1 | golgi glycoprotein 1 | -0.0438508 |
| FDPS | farnesyl diphosphate synthase | -0.0436156 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0435393 |
| LDLR | low density lipoprotein receptor | -0.0434366 |
| RPS15 | ribosomal protein S15 | -0.0411588 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0394843 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0391146 |
| HM13 | histocompatibility (minor) 13 | -0.0389315 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0389267 |
| RPS13 | ribosomal protein S13 | -0.0388991 |
| TMSB10 | thymosin beta 10 | -0.0384754 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0381381 |
| RPS10 | ribosomal protein S10 | -0.0381133 |
| PTK2 | protein tyrosine kinase 2 | -0.0370473 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0369288 |
| VMP1 | vacuole membrane protein 1 | -0.0369174 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0367869 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0366291 |
| RPS29 | ribosomal protein S29 | -0.036543 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0363571 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0363541 |
| CDK19 | cyclin-dependent kinase 19 | -0.0363516 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.036172 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0358987 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0358529 |
| RPL19 | ribosomal protein L19 | -0.0354939 |
| BBX | bobby sox homolog (Drosophila) | -0.0350843 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0348158 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0343275 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0342323 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0342138 |
| RPL34 | ribosomal protein L34 | -0.0341107 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0334882 |
| PRELID2 | PRELI domain containing 2 | -0.0334654 |
| RPL37A | ribosomal protein L37a | -0.0329545 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.032544 |
| CD2AP | CD2-associated protein | -0.0324653 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0322809 |
| SRP54 | signal recognition particle 54kDa | -0.0320321 |
| RPS23 | ribosomal protein S23 | -0.0315636 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0314524 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0310906 |
| CCNI | cyclin I | -0.0310639 |
| RPL38 | ribosomal protein L38 | -0.030929 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0305898 |
| RBM39 | RNA binding motif protein 39 | -0.0305703 |
| COG6 | component of oligomeric golgi complex 6 | -0.0303833 |
| WDR45B | WD repeat domain 45B | -0.030331 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0302332 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0300489 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0298118 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0297227 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296091 |
| ZNF638 | zinc finger protein 638 | -0.0293255 |
| TMEM41B | transmembrane protein 41B | -0.02931 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0290865 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0290028 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0283384 |
| RPL15 | ribosomal protein L15 | -0.0282168 |
| RPS19 | ribosomal protein S19 | -0.0281876 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0280846 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0276826 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0274495 |
| ZNF207 | zinc finger protein 207 | -0.0272146 |
| NOP58 | NOP58 ribonucleoprotein | -0.0267939 |
| SEC24D | SEC24 family member D | -0.0266767 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0266587 |
| RPS14 | ribosomal protein S14 | -0.026588 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0264534 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0264113 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0262892 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0262155 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0262062 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0260142 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0260064 |
| EP300 | E1A binding protein p300 | -0.025855 |
| RPS25 | ribosomal protein S25 | -0.0257475 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0257281 |
