| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.107699 |
| LMO7 | LIM domain 7 | 0.0994224 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.098581 |
| INTS6 | integrator complex subunit 6 | 0.0851152 |
| RPS12 | ribosomal protein S12 | 0.0610922 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0567452 |
| FTL | ferritin, light polypeptide | 0.0562437 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0549888 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0490832 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0475047 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0462327 |
| DST | dystonin | 0.0452505 |
| EXPH5 | exophilin 5 | 0.0452324 |
| ATXN1 | ataxin 1 | 0.0451756 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.042732 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0426707 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.040473 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0375304 |
| TXNRD1 | thioredoxin reductase 1 | 0.0373131 |
| PDZD8 | PDZ domain containing 8 | 0.0372269 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0363403 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0358226 |
| FBXO32 | F-box protein 32 | 0.0356558 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.035523 |
| SMAD3 | SMAD family member 3 | 0.0345869 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336814 |
| GOLGB1 | golgin B1 | 0.0325658 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0313642 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0306081 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0305111 |
| RPS3 | ribosomal protein S3 | 0.0303813 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0291087 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0284703 |
| ANXA1 | annexin A1 | 0.0281089 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0277511 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0268136 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0267402 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0265319 |
| PHF3 | PHD finger protein 3 | 0.0259525 |
| MCL1 | myeloid cell leukemia 1 | 0.0258449 |
| SLFN5 | schlafen family member 5 | 0.0257856 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0256009 |
| TLE4 | transducin-like enhancer of split 4 | 0.0252254 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0250938 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.024783 |
| OGA | O-GlcNAcase | 0.0246069 |
| VCL | vinculin | 0.023774 |
| NTN4 | netrin 4 | 0.0235513 |
| HYOU1 | hypoxia up-regulated 1 | 0.0233574 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232841 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0232003 |
| PLK2 | polo-like kinase 2 | 0.0225201 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0220556 |
| RASEF | RAS and EF-hand domain containing | 0.0220301 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0219238 |
| RPL4 | ribosomal protein L4 | 0.021362 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0212094 |
| RPS2 | ribosomal protein S2 | 0.0211975 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0211273 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0210993 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0208191 |
| FAT1 | FAT atypical cadherin 1 | 0.0208097 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0204756 |
| ATF3 | activating transcription factor 3 | 0.0203785 |
| SIK3 | SIK family kinase 3 | 0.0202482 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.020247 |
| RPL37A | ribosomal protein L37a | 0.0201497 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0200403 |
| RPL26 | ribosomal protein L26 | 0.0200031 |
| EFNB2 | ephrin-B2 | 0.0195812 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0195069 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0192944 |
| IPO7 | importin 7 | 0.0192443 |
| CANX | calnexin | 0.0191137 |
| HOMER1 | homer scaffolding protein 1 | 0.0190162 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.018997 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0187742 |
| SFTPA2 | surfactant protein A2 | 0.0187644 |
| RND3 | Rho family GTPase 3 | 0.0186439 |
| RPL31 | ribosomal protein L31 | 0.0185685 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0185655 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0184766 |
| EREG | epiregulin | 0.0184288 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0180088 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0177532 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0176629 |
| SET | SET nuclear proto-oncogene | 0.017495 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0174162 |
| KIF5B | kinesin family member 5B | 0.017413 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0173358 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0173082 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0172624 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0172558 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0171206 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0170431 |
| ENO1 | enolase 1, (alpha) | 0.0170404 |
| TRIB1 | tribbles pseudokinase 1 | 0.0170189 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0166916 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0166692 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0165822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181313 |
| PTMA | prothymosin, alpha | -0.135547 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107571 |
| POTEF | POTE ankyrin domain family, member F | -0.0968045 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0855772 |
| PLAUR | plasminogen activator, urokinase receptor | -0.084674 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0844683 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0833321 |
| WASF2 | WAS protein family, member 2 | -0.0821696 |
| LAMA4 | laminin, alpha 4 | -0.0816789 |
| TMSB10 | thymosin beta 10 | -0.0773495 |
| RPS6 | ribosomal protein S6 | -0.0751823 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0742736 |
| ACTG1 | actin gamma 1 | -0.0666192 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.065895 |
| LYZ | lysozyme | -0.0646414 |
| KRT19 | keratin 19, type I | -0.0612407 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0609993 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0602447 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0601704 |
| KRT8 | keratin 8, type II | -0.0601325 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0589606 |
| S100A6 | S100 calcium binding protein A6 | -0.0570791 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0563367 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0535706 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0516758 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.051346 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0493894 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0485818 |
| S100A10 | S100 calcium binding protein A10 | -0.0475508 |
| ACTN4 | actinin, alpha 4 | -0.046824 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0465426 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0463489 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0462682 |
| STK24 | serine/threonine kinase 24 | -0.0452523 |
| ANXA2 | annexin A2 | -0.044453 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0431392 |
| DIAPH2 | diaphanous-related formin 2 | -0.0429621 |
| PKM | pyruvate kinase, muscle | -0.0421734 |
| JUP | junction plakoglobin | -0.0416172 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0402085 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0392833 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0391895 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0391866 |
| RPS21 | ribosomal protein S21 | -0.0388757 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0388296 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0384405 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0383079 |
| RNF24 | ring finger protein 24 | -0.0382838 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0376766 |
| CD2AP | CD2-associated protein | -0.0373749 |
| KLK10 | kallikrein-related peptidase 10 | -0.036804 |
| DNM2 | dynamin 2 | -0.0362752 |
| ETV6 | ets variant 6 | -0.0360325 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0357685 |
| RNF213 | ring finger protein 213 | -0.0353245 |
| HMGA1 | high mobility group AT-hook 1 | -0.0352514 |
| LMNA | lamin A/C | -0.0351704 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0350168 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0347397 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0342363 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0329946 |
| AHNAK | AHNAK nucleoprotein | -0.0327714 |
| ASTN2 | astrotactin 2 | -0.0326802 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0325648 |
| EGR1 | early growth response 1 | -0.0321976 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0318931 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0318085 |
| SULF2 | sulfatase 2 | -0.0317924 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0316636 |
| ITGA6 | integrin, alpha 6 | -0.0316289 |
| RRBP1 | ribosome binding protein 1 | -0.0316025 |
| CBX3 | chromobox homolog 3 | -0.0315781 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0307687 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0304621 |
| CA12 | carbonic anhydrase XII | -0.0303254 |
| ANXA11 | annexin A11 | -0.0301023 |
| FRY | furry homolog (Drosophila) | -0.0298941 |
| RPS24 | ribosomal protein S24 | -0.0296281 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0291664 |
| RPS5 | ribosomal protein S5 | -0.029123 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0289771 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0289695 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0286598 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0286594 |
| RPL21 | ribosomal protein L21 | -0.0286243 |
| RDH13 | retinol dehydrogenase 13 (all-trans/9-cis) | -0.0285427 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0282809 |
| ZFP36 | ZFP36 ring finger protein | -0.0281852 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0280746 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0280442 |
| RPS11 | ribosomal protein S11 | -0.0280132 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0279132 |
| PATJ | PATJ crumbs cell polarity complex component | -0.027628 |
| WWC1 | WW and C2 domain containing 1 | -0.0276182 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0275968 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0272958 |
| CLDN4 | claudin 4 | -0.0272924 |
| TJP1 | tight junction protein 1 | -0.0272226 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0266784 |
