| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0704734 |
| TMC5 | transmembrane channel-like 5 | 0.058047 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.054813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0542382 |
| LMO7 | LIM domain 7 | 0.0509798 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0509005 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.050187 |
| FTL | ferritin, light polypeptide | 0.0475548 |
| RPS12 | ribosomal protein S12 | 0.0464278 |
| ENO1 | enolase 1, (alpha) | 0.0439036 |
| DSPP | dentin sialophosphoprotein | 0.0436966 |
| GDA | guanine deaminase | 0.0435999 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.043376 |
| SMAD3 | SMAD family member 3 | 0.0426334 |
| SEPTIN9 | septin 9 | 0.041506 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0413232 |
| ANXA1 | annexin A1 | 0.0402691 |
| SET | SET nuclear proto-oncogene | 0.0386206 |
| MYOF | myoferlin | 0.0378632 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0363986 |
| LDHA | lactate dehydrogenase A | 0.0354446 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0352961 |
| KRT18 | keratin 18, type I | 0.0352226 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0341418 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0339017 |
| PGK1 | phosphoglycerate kinase 1 | 0.0337995 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0331058 |
| NDRG1 | N-myc downstream regulated 1 | 0.0328071 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0324912 |
| ANXA11 | annexin A11 | 0.0321876 |
| DST | dystonin | 0.03198 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0304974 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0295306 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0292271 |
| ANKRD12 | ankyrin repeat domain 12 | 0.028927 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0289223 |
| AHR | aryl hydrocarbon receptor | 0.0280338 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0280291 |
| RPL35A | ribosomal protein L35a | 0.0278518 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0275931 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0271122 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0265424 |
| EZR | ezrin | 0.0255276 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0252401 |
| TFG | TRK-fused gene | 0.0252177 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0251837 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0251276 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0251172 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.024399 |
| RPS19 | ribosomal protein S19 | 0.0242278 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0240751 |
| SLTM | SAFB-like, transcription modulator | 0.0238464 |
| RPL23 | ribosomal protein L23 | 0.0237147 |
| RPL37A | ribosomal protein L37a | 0.0233817 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.0228781 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0227185 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0225441 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0222039 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0217327 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0214124 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210705 |
| ASPH | aspartate beta-hydroxylase | 0.0209851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0209681 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0209477 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0207382 |
| RPS27 | ribosomal protein S27 | 0.0206098 |
| TXNRD1 | thioredoxin reductase 1 | 0.0201359 |
| B2M | beta-2-microglobulin | 0.0196788 |
| RPS3 | ribosomal protein S3 | 0.0196618 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0195711 |
| HMGA1 | high mobility group AT-hook 1 | 0.0194882 |
| SFTPA2 | surfactant protein A2 | 0.0194057 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0193949 |
| LIMA1 | LIM domain and actin binding 1 | 0.0193338 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0193204 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0192714 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0192698 |
| EFNA5 | ephrin-A5 | 0.0190423 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0189569 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0187625 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.018668 |
| CLTC | clathrin, heavy chain (Hc) | 0.0185956 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.018358 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0182834 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0182275 |
| RPL30 | ribosomal protein L30 | 0.0179939 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0176654 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0175285 |
| ITGA6 | integrin, alpha 6 | 0.0174415 |
| RPS17 | ribosomal protein S17 | 0.0173371 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0172973 |
| FAM120A | family with sequence similarity 120A | 0.0170218 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0170046 |
| LIPH | lipase, member H | 0.0169144 |
| YBX1 | Y box binding protein 1 | 0.0169095 |
| JMJD1C | jumonji domain containing 1C | 0.0169016 |
| CALR | calreticulin | 0.0167778 |
| CTSB | cathepsin B | 0.0167453 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0166782 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0166463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.196032 |
| NPSR1 | neuropeptide S receptor 1 | -0.192955 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.099227 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0680946 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0645722 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0632817 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0592148 |
| PTMA | prothymosin, alpha | -0.0504288 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0467842 |
| EMP1 | epithelial membrane protein 1 | -0.0454271 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0397811 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.036483 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0346835 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0335472 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0321436 |
| H1-0 | H1.0 linker histone | -0.0309915 |
| S100A6 | S100 calcium binding protein A6 | -0.0283099 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0278584 |
| DEK | DEK proto-oncogene | -0.0272046 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0257559 |
| RRBP1 | ribosome binding protein 1 | -0.0256018 |
| KRT8 | keratin 8, type II | -0.0252824 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0248331 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0248032 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0243287 |
| RPS24 | ribosomal protein S24 | -0.0239004 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0235447 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.023439 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0233432 |
| ACTG1 | actin gamma 1 | -0.0231481 |
| ANXA2 | annexin A2 | -0.0231364 |
| CD2AP | CD2-associated protein | -0.0229577 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0227667 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0222343 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0222061 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0220728 |
| PRKCA | protein kinase C, alpha | -0.0218431 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0216911 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0215543 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0213669 |
| DIAPH2 | diaphanous-related formin 2 | -0.0212839 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0210952 |
| INSIG1 | insulin induced gene 1 | -0.02044 |
| RBM39 | RNA binding motif protein 39 | -0.0202826 |
| AGR2 | anterior gradient 2 | -0.0201421 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0200177 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0198852 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0194252 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0194111 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0193415 |
| MSI2 | musashi RNA-binding protein 2 | -0.0191827 |
| POF1B | premature ovarian failure, 1B | -0.0191654 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0185084 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0185069 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0183361 |
| HLA-C | major histocompatibility complex, class I, C | -0.018286 |
| RNF213 | ring finger protein 213 | -0.0182766 |
| TMEM123 | transmembrane protein 123 | -0.018245 |
| S100A10 | S100 calcium binding protein A10 | -0.0180968 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0180357 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0179383 |
| TFRC | transferrin receptor | -0.0177421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.017333 |
| ABHD17C | abhydrolase domain containing 17C | -0.0173186 |
| DENND1A | DENN/MADD domain containing 1A | -0.0172216 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0171809 |
| THOC2 | THO complex 2 | -0.017079 |
| PRSS3 | protease, serine, 3 | -0.0170715 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.016911 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0168822 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.016786 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0164547 |
| VCL | vinculin | -0.0162576 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0162306 |
| PHF14 | PHD finger protein 14 | -0.0160575 |
| TGFA | transforming growth factor, alpha | -0.0158696 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0158433 |
| HM13 | histocompatibility (minor) 13 | -0.0157471 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0157388 |
| POTEF | POTE ankyrin domain family, member F | -0.0157126 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0156591 |
| SSH2 | slingshot protein phosphatase 2 | -0.0156025 |
| CBX3 | chromobox homolog 3 | -0.0155895 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0154061 |
| TNRC18 | trinucleotide repeat containing 18 | -0.015365 |
| FUS | FUS RNA binding protein | -0.0152519 |
| KRT7 | keratin 7, type II | -0.0152146 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0151528 |
| HLA-B | major histocompatibility complex, class I, B | -0.0151089 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0151017 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0148754 |
| MTAP | methylthioadenosine phosphorylase | -0.014833 |
| NFIB | nuclear factor I/B | -0.0147647 |
| EXOC4 | exocyst complex component 4 | -0.0147456 |
| FASN | fatty acid synthase | -0.014546 |
| AUTS2 | autism susceptibility candidate 2 | -0.0145395 |
| PLCB4 | phospholipase C, beta 4 | -0.0142485 |
| CNKSR3 | CNKSR family member 3 | -0.014239 |
| GLG1 | golgi glycoprotein 1 | -0.0141329 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0141322 |
