| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erdafitinib _LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.129923 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.110466 |
| LDHA | lactate dehydrogenase A | 0.0876955 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0742785 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0742594 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0629549 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0586116 |
| ASPH | aspartate beta-hydroxylase | 0.0576694 |
| ENO1 | enolase 1, (alpha) | 0.057141 |
| MCL1 | myeloid cell leukemia 1 | 0.0558097 |
| NDRG1 | N-myc downstream regulated 1 | 0.054979 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0525688 |
| FMNL2 | formin-like 2 | 0.0517613 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.050276 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0502416 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0486177 |
| RPL23 | ribosomal protein L23 | 0.0457267 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0447624 |
| TPM3 | tropomyosin 3 | 0.0439204 |
| PKM | pyruvate kinase, muscle | 0.04233 |
| RPS2 | ribosomal protein S2 | 0.0415641 |
| VIM | vimentin | 0.0410122 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0407877 |
| RPL7 | ribosomal protein L7 | 0.0405774 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0403176 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0398209 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0383292 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0379049 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0377713 |
| PCBP2 | poly(rC) binding protein 2 | 0.0363314 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0355853 |
| RPS12 | ribosomal protein S12 | 0.0354307 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0348596 |
| ITGA6 | integrin, alpha 6 | 0.0344679 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333123 |
| POTEF | POTE ankyrin domain family, member F | 0.0331385 |
| SET | SET nuclear proto-oncogene | 0.0329943 |
| RPS8 | ribosomal protein S8 | 0.0313248 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0310022 |
| MKI67 | marker of proliferation Ki-67 | 0.0308612 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0287035 |
| YBX1 | Y box binding protein 1 | 0.0276698 |
| RPL3 | ribosomal protein L3 | 0.0266719 |
| RPS4X | ribosomal protein S4, X-linked | 0.026668 |
| FOXP1 | forkhead box P1 | 0.0261715 |
| EGR1 | early growth response 1 | 0.026134 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0260148 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0256625 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0255105 |
| CENPF | centromere protein F, 350/400kDa | 0.0251424 |
| RPL30 | ribosomal protein L30 | 0.025123 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0250085 |
| RACK1 | receptor for activated C kinase 1 | 0.024097 |
| OCA2 | oculocutaneous albinism II | 0.0240842 |
| RPS17 | ribosomal protein S17 | 0.0237634 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0236234 |
| ARFGEF3 | ARFGEF family member 3 | 0.0227082 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0226034 |
| CD44 | CD44 molecule (Indian blood group) | 0.0222812 |
| IPO7 | importin 7 | 0.0222774 |
| SFTPA2 | surfactant protein A2 | 0.0220291 |
| HMGA2 | high mobility group AT-hook 2 | 0.0218539 |
| RPLP0 | ribosomal protein, large, P0 | 0.0217189 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0216572 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0216561 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0216072 |
| NAV1 | neuron navigator 1 | 0.021443 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0213971 |
| FLNA | filamin A, alpha | 0.0213714 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0210293 |
| INTS6 | integrator complex subunit 6 | 0.0208165 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0206921 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0205621 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0203763 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0203224 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0202469 |
| SCRN1 | secernin 1 | 0.02013 |
| RPS27 | ribosomal protein S27 | 0.0201222 |
| STC1 | stanniocalcin 1 | 0.020036 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0198327 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0195976 |
| RAD51B | RAD51 paralog B | 0.0195861 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0194756 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0192933 |
| FOSL1 | FOS-like antigen 1 | 0.0192176 |
| CCDC80 | coiled-coil domain containing 80 | 0.0191469 |
| RPS7 | ribosomal protein S7 | 0.0191353 |
| EGFR | epidermal growth factor receptor | 0.0189157 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0187063 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0183345 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0180847 |
| PCDH11X | protocadherin 11 X-linked | 0.0180085 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178337 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0176177 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0173441 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0169063 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0167319 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0167182 |
| GOLGB1 | golgin B1 | 0.0166361 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0166082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153027 |
| MMP12 | matrix metallopeptidase 12 | -0.118854 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0725977 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0670306 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.055231 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0517947 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0498598 |
| RBM39 | RNA binding motif protein 39 | -0.0498352 |
| PTMA | prothymosin, alpha | -0.0485813 |
| PTK2 | protein tyrosine kinase 2 | -0.0455512 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0453675 |
| CD109 | CD109 molecule | -0.0443243 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0442764 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0442194 |
| PARD3 | par-3 family cell polarity regulator | -0.0439083 |
| ACTG1 | actin gamma 1 | -0.0414492 |
| ZNF292 | zinc finger protein 292 | -0.0405116 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0404867 |
| SPAG9 | sperm associated antigen 9 | -0.040093 |
| ANXA2 | annexin A2 | -0.0394796 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0387332 |
| TMSB10 | thymosin beta 10 | -0.0369935 |
| CDK17 | cyclin-dependent kinase 17 | -0.0369829 |
| HAS2 | hyaluronan synthase 2 | -0.0367667 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0362604 |
| QKI | QKI, KH domain containing, RNA binding | -0.0360991 |
| WDR45B | WD repeat domain 45B | -0.0360623 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0356577 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0353809 |
| NF1 | neurofibromin 1 | -0.03395 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0338305 |
| WDR43 | WD repeat domain 43 | -0.0335401 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0333516 |
| YBX3 | Y box binding protein 3 | -0.0321575 |
| ATP13A3 | ATPase type 13A3 | -0.0319665 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0314894 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0312055 |
| TLE4 | transducin-like enhancer of split 4 | -0.0310744 |
| NUP58 | nucleoporin 58 | -0.0303853 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0300919 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0300351 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0299091 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0285542 |
| USP3 | ubiquitin specific peptidase 3 | -0.0283623 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0278502 |
| THOC2 | THO complex 2 | -0.0275036 |
| RNF145 | ring finger protein 145 | -0.0271367 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0270921 |
| MED13L | mediator complex subunit 13-like | -0.0270792 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0268085 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0267917 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.026634 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0264844 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0263157 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0262597 |
| HDAC9 | histone deacetylase 9 | -0.025964 |
| HELZ | helicase with zinc finger | -0.0258937 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0255367 |
| GNAS | GNAS complex locus | -0.0254228 |
| RASA2 | RAS p21 protein activator 2 | -0.0251873 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0251647 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0248573 |
| CAVIN1 | caveolae associated protein 1 | -0.0247865 |
| NTM | neurotrimin | -0.0245731 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0242408 |
| RPS24 | ribosomal protein S24 | -0.0242345 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0240415 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0240355 |
| TMEM263 | transmembrane protein 263 | -0.0240253 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0239657 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0235918 |
| NOP58 | NOP58 ribonucleoprotein | -0.0233869 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0232407 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0230863 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0230471 |
| POU2F1 | POU class 2 homeobox 1 | -0.0230007 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0228346 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0228162 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0228005 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0226523 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0224891 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0224383 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0223884 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0223647 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0223491 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0222733 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.022145 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0220997 |
| RTN4 | reticulon 4 | -0.0219566 |
| SBF2 | SET binding factor 2 | -0.0219075 |
| FAM193A | family with sequence similarity 193, member A | -0.0218631 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0218304 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0217971 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0214297 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0211018 |
| PTCHD4 | patched domain containing 4 | -0.0210656 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0209417 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0208921 |
| CDK12 | cyclin-dependent kinase 12 | -0.0204764 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0203529 |
