| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.151391 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.105281 |
| FAT1 | FAT atypical cadherin 1 | 0.092857 |
| LDHA | lactate dehydrogenase A | 0.081478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.068441 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0681615 |
| KRT18 | keratin 18, type I | 0.0675417 |
| RPS12 | ribosomal protein S12 | 0.0643657 |
| ASPH | aspartate beta-hydroxylase | 0.0575795 |
| ENO1 | enolase 1, (alpha) | 0.0574414 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.052094 |
| EGFR | epidermal growth factor receptor | 0.047279 |
| DSPP | dentin sialophosphoprotein | 0.0461975 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0448501 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0433213 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0422588 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0419928 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.04083 |
| MYO1E | myosin IE | 0.0404824 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0404738 |
| TPM4 | tropomyosin 4 | 0.0390189 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0360255 |
| SET | SET nuclear proto-oncogene | 0.0354645 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0347733 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0347392 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0341468 |
| TPM3 | tropomyosin 3 | 0.0334523 |
| RPS8 | ribosomal protein S8 | 0.0323059 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0319391 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0314958 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0314898 |
| RAD51B | RAD51 paralog B | 0.0311401 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0308543 |
| MLEC | malectin | 0.0307263 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0305457 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0305404 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0299653 |
| SMYD3 | SET and MYND domain containing 3 | 0.029866 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0297827 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0289299 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0286526 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0285952 |
| RPL37A | ribosomal protein L37a | 0.028309 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.028023 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0279808 |
| FHIT | fragile histidine triad | 0.02729 |
| MT2A | metallothionein 2A | 0.0268101 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0264068 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0263739 |
| ITGA6 | integrin, alpha 6 | 0.0261665 |
| MUC13 | mucin 13, cell surface associated | 0.0258792 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.025532 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0255139 |
| LAMA4 | laminin, alpha 4 | 0.024945 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0247968 |
| INTS6 | integrator complex subunit 6 | 0.0240993 |
| RPS17 | ribosomal protein S17 | 0.0240585 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.024051 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0240212 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0239519 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0234724 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232861 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0232293 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0231639 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0225082 |
| KRT8 | keratin 8, type II | 0.0224841 |
| RPL9 | ribosomal protein L9 | 0.0224296 |
| SFTPA2 | surfactant protein A2 | 0.0222379 |
| TUBB4B | tubulin, beta 4B class IVb | 0.022157 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0219623 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0218975 |
| RPL3 | ribosomal protein L3 | 0.0216512 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0216509 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0215912 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0212448 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.021202 |
| RNF217 | ring finger protein 217 | 0.0210202 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0209145 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0207059 |
| NPSR1 | neuropeptide S receptor 1 | 0.0202986 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.01996 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0198275 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0197605 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0197557 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.019692 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0196367 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0193774 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.01907 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.018936 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0189303 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0189177 |
| MCL1 | myeloid cell leukemia 1 | 0.0188976 |
| LMO7 | LIM domain 7 | 0.0188578 |
| CALR | calreticulin | 0.0188491 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0187861 |
| SVIL | supervillin | 0.0187571 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.018405 |
| SLTM | SAFB-like, transcription modulator | 0.0182189 |
| SLK | STE20-like kinase | 0.0180585 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.017977 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.264801 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.248291 |
| PTMA | prothymosin, alpha | -0.0850304 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0642673 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0640655 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0605149 |
| GOLGA4 | golgin A4 | -0.0596271 |
| RNF145 | ring finger protein 145 | -0.051026 |
| GDF15 | growth differentiation factor 15 | -0.0500937 |
| WDR45B | WD repeat domain 45B | -0.0500036 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0492128 |
| RBM39 | RNA binding motif protein 39 | -0.0490495 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0463358 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0453887 |
| FAM13A | family with sequence similarity 13, member A | -0.042869 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0425382 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0418163 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0409883 |
| MED13L | mediator complex subunit 13-like | -0.0408995 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0407771 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0401758 |
| TXNIP | thioredoxin interacting protein | -0.0399771 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0392773 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0378638 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0373113 |
| GPHN | gephyrin | -0.0368204 |
| PIGR | polymeric immunoglobulin receptor | -0.0349033 |
| USP3 | ubiquitin specific peptidase 3 | -0.033483 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0332589 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0324021 |
| RPS6 | ribosomal protein S6 | -0.0318216 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305401 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0302089 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0297935 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0297148 |
| COG5 | component of oligomeric golgi complex 5 | -0.029587 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0289484 |
| SETD5 | SET domain containing 5 | -0.0289331 |
| RRBP1 | ribosome binding protein 1 | -0.02893 |
| S100P | S100 calcium binding protein P | -0.0281362 |
| ANXA2 | annexin A2 | -0.027943 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0270354 |
| RNF43 | ring finger protein 43 | -0.0264444 |
| TFG | TRK-fused gene | -0.0263649 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0261624 |
| PRRC1 | proline-rich coiled-coil 1 | -0.026101 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258741 |
| EREG | epiregulin | -0.0257389 |
| RLF | rearranged L-myc fusion | -0.0255442 |
| OGA | O-GlcNAcase | -0.0254397 |
| TMSB10 | thymosin beta 10 | -0.025248 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0251894 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0245645 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0242878 |
| AHNAK | AHNAK nucleoprotein | -0.0239865 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0238735 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0238454 |
| H1-0 | H1.0 linker histone | -0.0238076 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0236025 |
| NOP58 | NOP58 ribonucleoprotein | -0.0235281 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0232404 |
| ATF4 | activating transcription factor 4 | -0.023116 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0228166 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0227757 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0227348 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0226511 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0224877 |
| FNBP1L | formin binding protein 1-like | -0.0224633 |
| GSK3B | glycogen synthase kinase 3 beta | -0.02225 |
| HELZ | helicase with zinc finger | -0.0221894 |
| SRP54 | signal recognition particle 54kDa | -0.0220429 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0220084 |
| RPS24 | ribosomal protein S24 | -0.0219388 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0217673 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0217631 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0215013 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0211687 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0211661 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0210806 |
| CCNI | cyclin I | -0.0210648 |
| COPA | coatomer protein complex, subunit alpha | -0.0209598 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.020954 |
| INSIG1 | insulin induced gene 1 | -0.0209197 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0206978 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0206932 |
| LMAN1 | lectin, mannose-binding, 1 | -0.020579 |
| NF1 | neurofibromin 1 | -0.0204077 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0203135 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0200099 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0200039 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0199527 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0197581 |
| AGR2 | anterior gradient 2 | -0.0197034 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0196828 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0195256 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0195252 |
| HDLBP | high density lipoprotein binding protein | -0.019452 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0193711 |
| NEMF | nuclear export mediator factor | -0.0193255 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.019309 |
