| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0950546 |
| LDHA | lactate dehydrogenase A | 0.0918118 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0826389 |
| KRT18 | keratin 18, type I | 0.0761753 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.074569 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0736283 |
| RPS12 | ribosomal protein S12 | 0.0685581 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0674971 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.065485 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0628363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0624106 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0542183 |
| ASPH | aspartate beta-hydroxylase | 0.0532691 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0524089 |
| LMO7 | LIM domain 7 | 0.0459561 |
| RPL3 | ribosomal protein L3 | 0.0441949 |
| DSPP | dentin sialophosphoprotein | 0.0407589 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0380522 |
| MYO5B | myosin VB | 0.0369518 |
| DST | dystonin | 0.0358682 |
| NDRG1 | N-myc downstream regulated 1 | 0.0344071 |
| CANX | calnexin | 0.0338171 |
| RPL4 | ribosomal protein L4 | 0.0327258 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0324246 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0322461 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0309566 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304577 |
| RPS17 | ribosomal protein S17 | 0.0303564 |
| TPM3 | tropomyosin 3 | 0.03002 |
| SQSTM1 | sequestosome 1 | 0.0295431 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0287251 |
| ENO1 | enolase 1, (alpha) | 0.0286415 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0278845 |
| EGFR | epidermal growth factor receptor | 0.0275294 |
| SFTPA2 | surfactant protein A2 | 0.0275274 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0270386 |
| SET | SET nuclear proto-oncogene | 0.0269225 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0269202 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0267817 |
| SLTM | SAFB-like, transcription modulator | 0.0257326 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0256335 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0252086 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0251601 |
| CALR | calreticulin | 0.0247151 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0241748 |
| PDZD8 | PDZ domain containing 8 | 0.0241562 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0240155 |
| INTS6 | integrator complex subunit 6 | 0.0234683 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0230814 |
| UTRN | utrophin | 0.0229499 |
| RPL7 | ribosomal protein L7 | 0.0228917 |
| MYO1E | myosin IE | 0.0227754 |
| ARRDC3 | arrestin domain containing 3 | 0.0227746 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0226893 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0226867 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.022607 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0225552 |
| KRT8 | keratin 8, type II | 0.0224412 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0219076 |
| RPS7 | ribosomal protein S7 | 0.0214899 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0212787 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0202313 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0198537 |
| RPS27 | ribosomal protein S27 | 0.0198342 |
| IPO7 | importin 7 | 0.0196448 |
| RPS2 | ribosomal protein S2 | 0.0195714 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0195255 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0194537 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0190474 |
| RPS18 | ribosomal protein S18 | 0.0189663 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0186147 |
| PGM3 | phosphoglucomutase 3 | 0.0185268 |
| LRRC23 | leucine rich repeat containing 23 | 0.0185142 |
| WWOX | WW domain containing oxidoreductase | 0.0184755 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0183764 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0182588 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0179186 |
| MCL1 | myeloid cell leukemia 1 | 0.0178914 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0178271 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0176799 |
| GOLGB1 | golgin B1 | 0.0176636 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0174761 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0167439 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0165921 |
| MORF4L2 | mortality factor 4 like 2 | 0.0165005 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0163614 |
| FAT1 | FAT atypical cadherin 1 | 0.016144 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0161384 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0161267 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0160359 |
| RPS3A | ribosomal protein S3A | 0.0157963 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0155822 |
| MLEC | malectin | 0.0155737 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0155034 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.015497 |
| RND3 | Rho family GTPase 3 | 0.0151587 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0146333 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0145733 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0145657 |
| ANXA1 | annexin A1 | 0.0145026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.242953 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.190561 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171204 |
| PTMA | prothymosin, alpha | -0.131954 |
| RPS6 | ribosomal protein S6 | -0.120118 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.109003 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.10482 |
| TMSB10 | thymosin beta 10 | -0.101918 |
| CALB1 | calbindin 1, 28kDa | -0.0956611 |
| ACTG1 | actin gamma 1 | -0.0873306 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0856778 |
| RPLP0 | ribosomal protein, large, P0 | -0.0843284 |
| FLNB | filamin B, beta | -0.0822131 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.070009 |
| PLAC8 | placenta-specific 8 | -0.069821 |
| RPS24 | ribosomal protein S24 | -0.0668323 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0631115 |
| RPL35A | ribosomal protein L35a | -0.0593991 |
| RPS23 | ribosomal protein S23 | -0.059271 |
| MSI2 | musashi RNA-binding protein 2 | -0.0569695 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0546982 |
| ITGA6 | integrin, alpha 6 | -0.052678 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0522056 |
| POTEF | POTE ankyrin domain family, member F | -0.0489557 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0483979 |
| RPL13A | ribosomal protein L13a | -0.0482682 |
| VCL | vinculin | -0.0478976 |
| TRIM2 | tripartite motif containing 2 | -0.0468221 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0467484 |
| RPL19 | ribosomal protein L19 | -0.0461647 |
| MYOF | myoferlin | -0.0449422 |
| RBM25 | RNA binding motif protein 25 | -0.0441865 |
| RPLP2 | ribosomal protein, large, P2 | -0.0441162 |
| RPS21 | ribosomal protein S21 | -0.043094 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0428802 |
| RPS13 | ribosomal protein S13 | -0.0428307 |
| RPS29 | ribosomal protein S29 | -0.0420547 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0411016 |
| RPL9 | ribosomal protein L9 | -0.04081 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0398909 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0396298 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0393945 |
| RPS3 | ribosomal protein S3 | -0.0393045 |
| GDF15 | growth differentiation factor 15 | -0.0389882 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0385971 |
| GOLGA4 | golgin A4 | -0.0385476 |
| RPS25 | ribosomal protein S25 | -0.0384698 |
| ETNK1 | ethanolamine kinase 1 | -0.0382861 |
| PKP2 | plakophilin 2 | -0.0373529 |
| RPL28 | ribosomal protein L28 | -0.0372731 |
| RPL27A | ribosomal protein L27a | -0.0371949 |
| SETD5 | SET domain containing 5 | -0.0370297 |
| FOXO1 | forkhead box O1 | -0.0370237 |
| RPS16 | ribosomal protein S16 | -0.036971 |
| HLA-B | major histocompatibility complex, class I, B | -0.0362927 |
| PRSS3 | protease, serine, 3 | -0.0362854 |
| CCNI | cyclin I | -0.0358248 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0357617 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0355556 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0347388 |
| S100A6 | S100 calcium binding protein A6 | -0.0345068 |
| RPL34 | ribosomal protein L34 | -0.0342901 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0339121 |
| TCF12 | transcription factor 12 | -0.0337669 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0336629 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0334058 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0328988 |
| RPS11 | ribosomal protein S11 | -0.0325974 |
| NKTR | natural killer cell triggering receptor | -0.0325316 |
| FOXP1 | forkhead box P1 | -0.0322916 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0317558 |
| PCDHB16 | protocadherin beta 16 | -0.0315947 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0310134 |
| USP3 | ubiquitin specific peptidase 3 | -0.030707 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0306361 |
| THOC2 | THO complex 2 | -0.0305693 |
| CLDN4 | claudin 4 | -0.0302777 |
| RPL5 | ribosomal protein L5 | -0.0302525 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0299831 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0299481 |
| SHROOM3 | shroom family member 3 | -0.0298258 |
| DSG3 | desmoglein 3 | -0.0297462 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0297354 |
| SLMAP | sarcolemma associated protein | -0.0296264 |
| RPS27A | ribosomal protein S27a | -0.0295957 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.02934 |
| MED13L | mediator complex subunit 13-like | -0.0288495 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0287678 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0284076 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283797 |
| PERP | PERP, TP53 apoptosis effector | -0.0283394 |
| GPHN | gephyrin | -0.0282788 |
| NF1 | neurofibromin 1 | -0.0282602 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0282036 |
| RIGI | RNA sensor RIG-I | -0.0280485 |
| RPS5 | ribosomal protein S5 | -0.0279351 |
| RPLP1 | ribosomal protein, large, P1 | -0.0279218 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0278688 |
| CCNG1 | cyclin G1 | -0.0272334 |
| PDE8A | phosphodiesterase 8A | -0.0272105 |
