| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erdafitinib _NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.241447 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.238608 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.202352 |
| VIM | vimentin | 0.107821 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0889659 |
| TMSB10 | thymosin beta 10 | 0.0849084 |
| TPM3 | tropomyosin 3 | 0.0845814 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0775589 |
| PTMA | prothymosin, alpha | 0.0700434 |
| TPI1 | triosephosphate isomerase 1 | 0.0695525 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0676888 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0670895 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0612985 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0605276 |
| LDHA | lactate dehydrogenase A | 0.0589922 |
| KRT18 | keratin 18, type I | 0.0536655 |
| RAD51B | RAD51 paralog B | 0.052574 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0521531 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0520937 |
| ATP11A | ATPase, class VI, type 11A | 0.050791 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0506286 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0492099 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0488521 |
| ENO1 | enolase 1, (alpha) | 0.0485172 |
| UBC | ubiquitin C | 0.04838 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0475845 |
| RPS8 | ribosomal protein S8 | 0.0454594 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0447806 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0442339 |
| RPLP1 | ribosomal protein, large, P1 | 0.0438082 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0434475 |
| GRAMD1B | GRAM domain containing 1B | 0.0427974 |
| RPL37 | ribosomal protein L37 | 0.0416478 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0413413 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0403237 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0397548 |
| DSPP | dentin sialophosphoprotein | 0.0387856 |
| RPL23 | ribosomal protein L23 | 0.0379072 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0373053 |
| RPS19 | ribosomal protein S19 | 0.037119 |
| RPS2 | ribosomal protein S2 | 0.0367336 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0365208 |
| RPLP0 | ribosomal protein, large, P0 | 0.0362434 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0362031 |
| PKM | pyruvate kinase, muscle | 0.0353742 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0351347 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0345338 |
| PGK1 | phosphoglycerate kinase 1 | 0.0343008 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0339911 |
| SET | SET nuclear proto-oncogene | 0.0338518 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0334529 |
| RPS4X | ribosomal protein S4, X-linked | 0.0332525 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0331146 |
| YBX1 | Y box binding protein 1 | 0.0330246 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0327474 |
| MACROD2 | MACRO domain containing 2 | 0.0321384 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0320207 |
| PFN1 | profilin 1 | 0.031944 |
| RANBP2 | RAN binding protein 2 | 0.03193 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0316397 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0314761 |
| MYOF | myoferlin | 0.0310995 |
| MORF4L2 | mortality factor 4 like 2 | 0.0306782 |
| RPS21 | ribosomal protein S21 | 0.0304642 |
| LDHB | lactate dehydrogenase B | 0.0304375 |
| RPL11 | ribosomal protein L11 | 0.0303178 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0297008 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0294986 |
| YBX3 | Y box binding protein 3 | 0.0293314 |
| PYGL | phosphorylase, glycogen, liver | 0.0292679 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0292387 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0288333 |
| STAG2 | stromal antigen 2 | 0.0283453 |
| RRM2 | ribonucleotide reductase M2 | 0.0283155 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0282624 |
| GPHN | gephyrin | 0.0282185 |
| RPS27 | ribosomal protein S27 | 0.028039 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0274819 |
| STC1 | stanniocalcin 1 | 0.0273063 |
| SMYD3 | SET and MYND domain containing 3 | 0.0272755 |
| RPL36 | ribosomal protein L36 | 0.0269985 |
| CANX | calnexin | 0.0269374 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0269247 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0268155 |
| MSH2 | mutS homolog 2 | 0.0266088 |
| CEP250 | centrosomal protein 250kDa | 0.0263069 |
| GLO1 | glyoxalase I | 0.026282 |
| HDLBP | high density lipoprotein binding protein | 0.026268 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0262235 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0261765 |
| KLF6 | Kruppel-like factor 6 | 0.0261255 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0258326 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0257565 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0257217 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0256223 |
| MSH6 | mutS homolog 6 | 0.0255666 |
| RPL8 | ribosomal protein L8 | 0.025132 |
| RPL26 | ribosomal protein L26 | 0.0248641 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0247343 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0246518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0502569 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.040558 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0375405 |
| NABP1 | nucleic acid binding protein 1 | -0.0369627 |
| NF1 | neurofibromin 1 | -0.0346825 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0323926 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0322922 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0314839 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0310237 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0301156 |
| CCDC91 | coiled-coil domain containing 91 | -0.0300392 |
| EXOC4 | exocyst complex component 4 | -0.0295618 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0290274 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0284524 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0257607 |
| USP34 | ubiquitin specific peptidase 34 | -0.025631 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0253225 |
| RNF145 | ring finger protein 145 | -0.0242781 |
| PTK2 | protein tyrosine kinase 2 | -0.0227639 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0227536 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0226454 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0223043 |
| ETNK1 | ethanolamine kinase 1 | -0.0220803 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0217865 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.02153 |
| CDK17 | cyclin-dependent kinase 17 | -0.0214687 |
| HDAC8 | histone deacetylase 8 | -0.020824 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0202441 |
| THOC2 | THO complex 2 | -0.0201606 |
| ZNF644 | zinc finger protein 644 | -0.0197991 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0197454 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0196554 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0193933 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0191742 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0189091 |
| NOTCH2 | notch 2 | -0.0188978 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0186402 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0183638 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0183604 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0183463 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0181085 |
| CCNL1 | cyclin L1 | -0.018074 |
| ZNF638 | zinc finger protein 638 | -0.0180052 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0179382 |
| COG5 | component of oligomeric golgi complex 5 | -0.0178508 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0177326 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0177318 |
| RNF213 | ring finger protein 213 | -0.0175233 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0174522 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0174422 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.017401 |
| BRD4 | bromodomain containing 4 | -0.0172438 |
| EGR1 | early growth response 1 | -0.0172228 |
| TAPBP | TAP binding protein (tapasin) | -0.0171444 |
| PPHLN1 | periphilin 1 | -0.0166322 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0164728 |
| WDR43 | WD repeat domain 43 | -0.0164333 |
| FNIP1 | folliculin interacting protein 1 | -0.0162834 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0161248 |
| COPA | coatomer protein complex, subunit alpha | -0.0161196 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0159946 |
| TMEM165 | transmembrane protein 165 | -0.0158259 |
| RBM39 | RNA binding motif protein 39 | -0.0157009 |
| XPO6 | exportin 6 | -0.0156012 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0152987 |
| POGZ | pogo transposable element with ZNF domain | -0.0152648 |
| RASA2 | RAS p21 protein activator 2 | -0.0151207 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0151088 |
| NKTR | natural killer cell triggering receptor | -0.0150977 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0150513 |
| CUL3 | cullin 3 | -0.015037 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0150108 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0146786 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0145691 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0145233 |
| ZNF148 | zinc finger protein 148 | -0.0145066 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0144987 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0144967 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0144666 |
| NLGN1 | neuroligin 1 | -0.0142965 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0142714 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0142608 |
| PCNX1 | pecanex 1 | -0.0142604 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0142263 |
| SNX9 | sorting nexin 9 | -0.0142211 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0142186 |
| SNX13 | sorting nexin 13 | -0.0141999 |
| DENND5B | DENN/MADD domain containing 5B | -0.0139964 |
| SCAF8 | SR-related CTD-associated factor 8 | -0.0139947 |
| TXNRD1 | thioredoxin reductase 1 | -0.0139548 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0139349 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0139206 |
| VCL | vinculin | -0.0138874 |
| MEF2D | myocyte enhancer factor 2D | -0.0138173 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.0137684 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0136617 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0136581 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0135963 |
| AGRN | agrin | -0.0135808 |
| KMT5B | lysine methyltransferase 5B | -0.0134581 |
