| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.150557 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104775 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0835827 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0832836 |
| NDRG1 | N-myc downstream regulated 1 | 0.0817921 |
| RPS12 | ribosomal protein S12 | 0.0703392 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.065714 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0615133 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0609652 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0608205 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0570601 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0559839 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0557135 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0529716 |
| ENO1 | enolase 1, (alpha) | 0.0529588 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0515866 |
| RPS3 | ribosomal protein S3 | 0.0493941 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0476202 |
| MCL1 | myeloid cell leukemia 1 | 0.0467519 |
| LDHA | lactate dehydrogenase A | 0.0464991 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0460907 |
| RACK1 | receptor for activated C kinase 1 | 0.043161 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0431019 |
| FTL | ferritin, light polypeptide | 0.0402633 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0357774 |
| RPS17 | ribosomal protein S17 | 0.0352309 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.035111 |
| RPL37A | ribosomal protein L37a | 0.0333379 |
| TSC22D2 | TSC22 domain family, member 2 | 0.033001 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0326472 |
| INTS6 | integrator complex subunit 6 | 0.0324157 |
| RPL35A | ribosomal protein L35a | 0.0314635 |
| EGR1 | early growth response 1 | 0.031353 |
| CD109 | CD109 molecule | 0.0305872 |
| RPL30 | ribosomal protein L30 | 0.0302431 |
| DSPP | dentin sialophosphoprotein | 0.0296224 |
| SET | SET nuclear proto-oncogene | 0.0291941 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0289666 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0271574 |
| GOLGB1 | golgin B1 | 0.0271531 |
| HDAC9 | histone deacetylase 9 | 0.0266954 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0264049 |
| RPL9 | ribosomal protein L9 | 0.0263262 |
| RPS2 | ribosomal protein S2 | 0.0262361 |
| RPL7 | ribosomal protein L7 | 0.0261026 |
| TPM3 | tropomyosin 3 | 0.0260911 |
| RPL11 | ribosomal protein L11 | 0.0256515 |
| RPS8 | ribosomal protein S8 | 0.025434 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0250705 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0247403 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0240176 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0239804 |
| FAM13A | family with sequence similarity 13, member A | 0.0237687 |
| CANX | calnexin | 0.0236451 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0236061 |
| RPL3 | ribosomal protein L3 | 0.0232943 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0231396 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.023124 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.022829 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0225587 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0224387 |
| SGMS2 | sphingomyelin synthase 2 | 0.0222984 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0219979 |
| VEGFA | vascular endothelial growth factor A | 0.0217185 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0216968 |
| NABP1 | nucleic acid binding protein 1 | 0.0216081 |
| PCBP2 | poly(rC) binding protein 2 | 0.0215828 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0213855 |
| SPAG9 | sperm associated antigen 9 | 0.0213492 |
| YBX1 | Y box binding protein 1 | 0.0208989 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0205025 |
| HSPA8 | heat shock 70kDa protein 8 | 0.020435 |
| FLNB | filamin B, beta | 0.0201269 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0199132 |
| RPS13 | ribosomal protein S13 | 0.0195889 |
| DST | dystonin | 0.0195028 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0194797 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0194629 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0193367 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0193286 |
| PCM1 | pericentriolar material 1 | 0.0191082 |
| ARRDC3 | arrestin domain containing 3 | 0.0189817 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0187309 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0184873 |
| RPS27 | ribosomal protein S27 | 0.0184838 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0184199 |
| MSN | moesin | 0.0183042 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0182579 |
| EFNA5 | ephrin-A5 | 0.018201 |
| IRS2 | insulin receptor substrate 2 | 0.0180902 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0180328 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0180109 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0176578 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0174335 |
| KIAA1217 | KIAA1217 | 0.0173796 |
| RPL23 | ribosomal protein L23 | 0.0171716 |
| FNIP1 | folliculin interacting protein 1 | 0.0171036 |
| BRD2 | bromodomain containing 2 | 0.0167663 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0167488 |
| NRDC | nardilysin convertase | 0.01673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174226 |
| ACTG1 | actin gamma 1 | -0.114085 |
| TMSB10 | thymosin beta 10 | -0.0987997 |
| PTMA | prothymosin, alpha | -0.0974175 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0969563 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0755447 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0619513 |
| CCND1 | cyclin D1 | -0.0615919 |
| S100A6 | S100 calcium binding protein A6 | -0.0601948 |
| FN1 | fibronectin 1 | -0.0597606 |
| LMO7 | LIM domain 7 | -0.0596802 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0588424 |
| CD2AP | CD2-associated protein | -0.0552676 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0495359 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0487566 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0468843 |
| AHNAK | AHNAK nucleoprotein | -0.0413428 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0394658 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0391427 |
| TMSB4X | thymosin beta 4, X-linked | -0.0389688 |
| S100A10 | S100 calcium binding protein A10 | -0.0386225 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0375491 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0330192 |
| RRBP1 | ribosome binding protein 1 | -0.0318888 |
| RBM25 | RNA binding motif protein 25 | -0.0315478 |
| H1-0 | H1.0 linker histone | -0.0301599 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0296191 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0294385 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0291728 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0291421 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.028717 |
| KRT7 | keratin 7, type II | -0.0284666 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0280865 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0275142 |
| LMNA | lamin A/C | -0.0274238 |
| SDC4 | syndecan 4 | -0.0272548 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0268192 |
| POTEF | POTE ankyrin domain family, member F | -0.0266013 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0265915 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265886 |
| MYO6 | myosin VI | -0.0265335 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0263577 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0262514 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.026222 |
| HLA-B | major histocompatibility complex, class I, B | -0.0257492 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0256892 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0253594 |
| FAM3C | family with sequence similarity 3, member C | -0.0251611 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.025145 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0242525 |
| FAM162A | family with sequence similarity 162, member A | -0.023757 |
| DSG2 | desmoglein 2 | -0.0236752 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0222286 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0221954 |
| GNAS | GNAS complex locus | -0.0220494 |
| TMEM123 | transmembrane protein 123 | -0.0219613 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0216826 |
| F11R | F11 receptor | -0.0216345 |
| UBC | ubiquitin C | -0.0216256 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0214593 |
| MAP4 | microtubule-associated protein 4 | -0.021103 |
| ANTXR2 | anthrax toxin receptor 2 | -0.021037 |
| OGA | O-GlcNAcase | -0.0210076 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.020596 |
| ANXA2 | annexin A2 | -0.0203252 |
| RPS21 | ribosomal protein S21 | -0.0200801 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0200337 |
| CAVIN1 | caveolae associated protein 1 | -0.0199972 |
| SLMAP | sarcolemma associated protein | -0.0199615 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0195592 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0194743 |
| TMEM263 | transmembrane protein 263 | -0.0194224 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0193274 |
| USP3 | ubiquitin specific peptidase 3 | -0.0192729 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0191631 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0190297 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0190141 |
| WASF2 | WAS protein family, member 2 | -0.0189359 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0188844 |
| RPL34 | ribosomal protein L34 | -0.0188244 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0186426 |
| CDCP1 | CUB domain containing protein 1 | -0.0183887 |
| FRMD5 | FERM domain containing 5 | -0.0181065 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0180961 |
| CALU | calumenin | -0.0176936 |
| DEK | DEK proto-oncogene | -0.0176369 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0175261 |
| TPM4 | tropomyosin 4 | -0.0174513 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0170091 |
| TXNRD1 | thioredoxin reductase 1 | -0.0169753 |
| RASA2 | RAS p21 protein activator 2 | -0.0169288 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0169036 |
| RASAL2 | RAS protein activator like 2 | -0.016869 |
| CCNI | cyclin I | -0.0167919 |
| S100A11 | S100 calcium binding protein A11 | -0.0167867 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0167526 |
| RBM39 | RNA binding motif protein 39 | -0.0167239 |
| MT2A | metallothionein 2A | -0.016444 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0163762 |
| RPS24 | ribosomal protein S24 | -0.0163475 |
