| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.157088 |
| RPS12 | ribosomal protein S12 | 0.153176 |
| RPL35A | ribosomal protein L35a | 0.129339 |
| ENO1 | enolase 1, (alpha) | 0.121318 |
| SFTPA2 | surfactant protein A2 | 0.120763 |
| RPS3 | ribosomal protein S3 | 0.0950759 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0950238 |
| RPL37A | ribosomal protein L37a | 0.0916584 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0888166 |
| LDHA | lactate dehydrogenase A | 0.0860349 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0774089 |
| RPS16 | ribosomal protein S16 | 0.0749628 |
| FTL | ferritin, light polypeptide | 0.0727999 |
| RPS8 | ribosomal protein S8 | 0.069169 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0677962 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0676577 |
| RPS17 | ribosomal protein S17 | 0.0666586 |
| INTS6 | integrator complex subunit 6 | 0.0665195 |
| RPLP1 | ribosomal protein, large, P1 | 0.065812 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0643472 |
| SET | SET nuclear proto-oncogene | 0.0617717 |
| DST | dystonin | 0.0611112 |
| RPL30 | ribosomal protein L30 | 0.0601479 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0583399 |
| VIM | vimentin | 0.0567409 |
| MT2A | metallothionein 2A | 0.0554466 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0554243 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0553726 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0520663 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0518473 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0518444 |
| EGFR | epidermal growth factor receptor | 0.0514985 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0505784 |
| RPL11 | ribosomal protein L11 | 0.0504324 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0501785 |
| RPL31 | ribosomal protein L31 | 0.0490632 |
| YBX1 | Y box binding protein 1 | 0.048548 |
| RPL26 | ribosomal protein L26 | 0.0477105 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0464622 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0462956 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0461607 |
| RACK1 | receptor for activated C kinase 1 | 0.0459486 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0451139 |
| RPS27 | ribosomal protein S27 | 0.0428606 |
| RPL23 | ribosomal protein L23 | 0.0425413 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0424299 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0415141 |
| EGR1 | early growth response 1 | 0.0413193 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0412213 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0408685 |
| PGK1 | phosphoglycerate kinase 1 | 0.0406395 |
| RPL7 | ribosomal protein L7 | 0.0399945 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0394399 |
| RPS27A | ribosomal protein S27a | 0.0394202 |
| GOLGB1 | golgin B1 | 0.0384731 |
| RPS2 | ribosomal protein S2 | 0.0383237 |
| RPL37 | ribosomal protein L37 | 0.0381653 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0380026 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0373412 |
| RPS13 | ribosomal protein S13 | 0.0372309 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0358312 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0354819 |
| PKM | pyruvate kinase, muscle | 0.0345375 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0338814 |
| RPS20 | ribosomal protein S20 | 0.0332125 |
| RPL12 | ribosomal protein L12 | 0.0329015 |
| RPS19 | ribosomal protein S19 | 0.0328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0324555 |
| ANGPTL4 | angiopoietin-like 4 | 0.0323254 |
| NDRG1 | N-myc downstream regulated 1 | 0.0322727 |
| MORF4L2 | mortality factor 4 like 2 | 0.0315915 |
| B2M | beta-2-microglobulin | 0.0312885 |
| CTBP2 | C-terminal binding protein 2 | 0.0312529 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0309478 |
| FAT1 | FAT atypical cadherin 1 | 0.0302478 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0301479 |
| MCL1 | myeloid cell leukemia 1 | 0.0301069 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0298562 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0290494 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0289894 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0284601 |
| TLN1 | talin 1 | 0.0282694 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0275418 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.027167 |
| CALR | calreticulin | 0.0268539 |
| HLA-A | major histocompatibility complex, class I, A | 0.0268447 |
| TPM3 | tropomyosin 3 | 0.0262526 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0260163 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0257292 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256457 |
| RPL9 | ribosomal protein L9 | 0.0254266 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.025321 |
| MLEC | malectin | 0.0249954 |
| RPL5 | ribosomal protein L5 | 0.0248192 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0247197 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0245992 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0244532 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0243557 |
| FLNB | filamin B, beta | 0.0242429 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0242341 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | -0.168535 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142149 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.139963 |
| PTMA | prothymosin, alpha | -0.114995 |
| VCL | vinculin | -0.0929868 |
| AHNAK | AHNAK nucleoprotein | -0.0899174 |
| ACTN4 | actinin, alpha 4 | -0.0876451 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0832037 |
| RTN4 | reticulon 4 | -0.0755671 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0700936 |
| FBL | fibrillarin | -0.0638751 |
| CD44 | CD44 molecule (Indian blood group) | -0.0611977 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0585047 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0582778 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0542497 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.053697 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0536911 |
| JMJD1C | jumonji domain containing 1C | -0.0493835 |
| ACTG1 | actin gamma 1 | -0.0410969 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0406236 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0381606 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0375057 |
| LMNA | lamin A/C | -0.0357132 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0353785 |
| TMEM41B | transmembrane protein 41B | -0.034993 |
| CDCP1 | CUB domain containing protein 1 | -0.0349484 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0347367 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.034566 |
| TMEM123 | transmembrane protein 123 | -0.0336836 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0318476 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.031577 |
| CTSD | cathepsin D | -0.0313256 |
| ANLN | anillin, actin binding protein | -0.0309099 |
| PDE10A | phosphodiesterase 10A | -0.0302847 |
| DEK | DEK proto-oncogene | -0.0294475 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0294278 |
| CCND1 | cyclin D1 | -0.0285789 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.028258 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0274415 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0270852 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0268636 |
| TXNRD1 | thioredoxin reductase 1 | -0.0267143 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0266772 |
| FOSL1 | FOS-like antigen 1 | -0.0265978 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.025758 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0254146 |
| FHL2 | four and a half LIM domains 2 | -0.0249558 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0249103 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0246217 |
| ATP13A3 | ATPase type 13A3 | -0.0244327 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.023832 |
| ANXA2 | annexin A2 | -0.023715 |
| NUP98 | nucleoporin 98kDa | -0.0237068 |
| PYGB | phosphorylase, glycogen; brain | -0.0234809 |
| VMP1 | vacuole membrane protein 1 | -0.0231648 |
| AFAP1 | actin filament associated protein 1 | -0.0230274 |
| OSMR | oncostatin M receptor | -0.02302 |
| SEPTIN10 | septin 10 | -0.0230056 |
| KLF6 | Kruppel-like factor 6 | -0.0228595 |
| UBC | ubiquitin C | -0.0226178 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0224866 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0222988 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0222904 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0221853 |
| THOC2 | THO complex 2 | -0.0221437 |
| MYO10 | myosin X | -0.0218763 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0217894 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0217812 |
| CBX3 | chromobox homolog 3 | -0.0216528 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0212661 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211874 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0211833 |
| WDR45B | WD repeat domain 45B | -0.0211548 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0210045 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0209012 |
| RBM39 | RNA binding motif protein 39 | -0.0209002 |
| YBX3 | Y box binding protein 3 | -0.0207377 |
| MED13L | mediator complex subunit 13-like | -0.0205699 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0205351 |
| RPS24 | ribosomal protein S24 | -0.0204565 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0204364 |
| TPX2 | TPX2, microtubule-associated | -0.0203984 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0202814 |
| RNF38 | ring finger protein 38 | -0.0202277 |
| RASAL2 | RAS protein activator like 2 | -0.0201265 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0200936 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0200314 |
| CDC42SE2 | CDC42 small effector 2 | -0.0199937 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0199548 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0198924 |
| TMSB10 | thymosin beta 10 | -0.0197199 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.019679 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0196524 |
| TUBB | tubulin, beta class I | -0.0196445 |
| CDK19 | cyclin-dependent kinase 19 | -0.0193808 |
| RBM25 | RNA binding motif protein 25 | -0.0193669 |
| ZNF217 | zinc finger protein 217 | -0.0189874 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0189782 |
| CD2AP | CD2-associated protein | -0.0188003 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0187958 |
