| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.246259 |
| STC1 | stanniocalcin 1 | 0.146137 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.132334 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.131788 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.117556 |
| VIM | vimentin | 0.111731 |
| ENO1 | enolase 1, (alpha) | 0.111126 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.108712 |
| LDHA | lactate dehydrogenase A | 0.0893579 |
| HLA-B | major histocompatibility complex, class I, B | 0.0830815 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0830053 |
| CD44 | CD44 molecule (Indian blood group) | 0.0805403 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.076557 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0757845 |
| NDRG1 | N-myc downstream regulated 1 | 0.0737335 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0727739 |
| EGR1 | early growth response 1 | 0.0722972 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0697546 |
| FTL | ferritin, light polypeptide | 0.0693905 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0644369 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0640222 |
| SFTPA2 | surfactant protein A2 | 0.0635924 |
| HLA-A | major histocompatibility complex, class I, A | 0.063549 |
| HDAC9 | histone deacetylase 9 | 0.0635138 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0625256 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0618372 |
| FAT1 | FAT atypical cadherin 1 | 0.061827 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0613283 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0610656 |
| CALR | calreticulin | 0.0604025 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0598725 |
| RND3 | Rho family GTPase 3 | 0.0560209 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0546123 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0545675 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0533283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0522053 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0520612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.051927 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0517198 |
| MCL1 | myeloid cell leukemia 1 | 0.0513576 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0511753 |
| INHBA | inhibin, beta A | 0.0501181 |
| SMAD3 | SMAD family member 3 | 0.0496412 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0490107 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.04816 |
| SP100 | SP100 nuclear antigen | 0.0478599 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0463417 |
| MMP2 | matrix metallopeptidase 2 | 0.0461997 |
| LOXL2 | lysyl oxidase-like 2 | 0.0460696 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0460512 |
| RPS17 | ribosomal protein S17 | 0.0459085 |
| COL1A2 | collagen, type I, alpha 2 | 0.0454001 |
| RPS8 | ribosomal protein S8 | 0.0447867 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.043469 |
| HLA-E | major histocompatibility complex, class I, E | 0.0432829 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0431973 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.04268 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0420023 |
| NAV2 | neuron navigator 2 | 0.0416482 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0407714 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0407385 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0398767 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.038771 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0385727 |
| SQSTM1 | sequestosome 1 | 0.0382697 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0378816 |
| DST | dystonin | 0.0372728 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.037266 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0370325 |
| RPL37A | ribosomal protein L37a | 0.0364268 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0360747 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.036026 |
| VEGFA | vascular endothelial growth factor A | 0.0359436 |
| RPL35A | ribosomal protein L35a | 0.0357522 |
| IL6 | interleukin 6 | 0.0356312 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0354941 |
| RPS12 | ribosomal protein S12 | 0.0350055 |
| ARRDC3 | arrestin domain containing 3 | 0.0347109 |
| TWIST2 | twist family bHLH transcription factor 2 | 0.0342798 |
| JUN | jun proto-oncogene | 0.0342788 |
| AGBL1 | ATP/GTP binding protein-like 1 | 0.0341144 |
| CTSB | cathepsin B | 0.0340501 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0339434 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0339317 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0335469 |
| TPM3 | tropomyosin 3 | 0.033288 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0324866 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0323918 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0322337 |
| CD109 | CD109 molecule | 0.0320907 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.031941 |
| RLF | rearranged L-myc fusion | 0.0319115 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0317367 |
| HMGA2 | high mobility group AT-hook 2 | 0.0317253 |
| RPL12 | ribosomal protein L12 | 0.0314124 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0307429 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303314 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0301636 |
| RPL26 | ribosomal protein L26 | 0.029986 |
| ANGPTL4 | angiopoietin-like 4 | 0.0298083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.1468 |
| MT2A | metallothionein 2A | -0.1048 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0745325 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.067569 |
| COL1A1 | collagen, type I, alpha 1 | -0.0473514 |
| FRMD4A | FERM domain containing 4A | -0.0418843 |
| COL7A1 | collagen, type VII, alpha 1 | -0.041699 |
| SETD5 | SET domain containing 5 | -0.0389836 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0368166 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0354014 |
| AHNAK | AHNAK nucleoprotein | -0.0353242 |
| CENPF | centromere protein F, 350/400kDa | -0.0346266 |
| TMEM263 | transmembrane protein 263 | -0.0345912 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0343101 |
| POTEF | POTE ankyrin domain family, member F | -0.032991 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0326665 |
| TPX2 | TPX2, microtubule-associated | -0.0307918 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0290225 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0285506 |
| TNS3 | tensin 3 | -0.0279766 |
| TFG | TRK-fused gene | -0.0278102 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0275216 |
| RAD51B | RAD51 paralog B | -0.0272662 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.025815 |
| SEC24D | SEC24 family member D | -0.0252647 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0250645 |
| DIAPH3 | diaphanous-related formin 3 | -0.0248852 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0242998 |
| MSN | moesin | -0.0239955 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0236794 |
| RRBP1 | ribosome binding protein 1 | -0.0235569 |
| NKTR | natural killer cell triggering receptor | -0.0234072 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0231283 |
| RBM39 | RNA binding motif protein 39 | -0.0226667 |
| RAB2A | RAB2A, member RAS oncogene family | -0.022349 |
| CENPE | centromere protein E, 312kDa | -0.0222682 |
| DOCK10 | dedicator of cytokinesis 10 | -0.0217275 |
| SGO2 | shugoshin 2 | -0.0216569 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.021483 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0213466 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0212888 |
| FAM20C | family with sequence similarity 20, member C | -0.0212152 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0211735 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0210447 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207696 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0205174 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0202778 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0201784 |
| CDC27 | cell division cycle 27 | -0.0197258 |
| TENM4 | teneurin transmembrane protein 4 | -0.019668 |
| VCL | vinculin | -0.0196148 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0193974 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0192972 |
| KIF4A | kinesin family member 4A | -0.0192962 |
| ZNF292 | zinc finger protein 292 | -0.0192126 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0191975 |
| GLIS3 | GLIS family zinc finger 3 | -0.01889 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0184718 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0184568 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0175876 |
| TMEM39A | transmembrane protein 39A | -0.0175122 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.017511 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0174485 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0174479 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0173782 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0172969 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.017292 |
| RBM6 | RNA binding motif protein 6 | -0.0169712 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0169528 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0169431 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0167932 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0167019 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0166588 |
| AFAP1 | actin filament associated protein 1 | -0.0166194 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0165128 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0163161 |
| CKAP2 | cytoskeleton associated protein 2 | -0.016237 |
| KIAA1328 | KIAA1328 | -0.0161189 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0159906 |
| GNAS | GNAS complex locus | -0.0158146 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0157086 |
| GOLGA3 | golgin A3 | -0.0156594 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0156139 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0155141 |
| ANLN | anillin, actin binding protein | -0.0154907 |
| NUMB | numb homolog (Drosophila) | -0.0152782 |
| MKI67 | marker of proliferation Ki-67 | -0.0151764 |
| KNL1 | kinetochore scaffold 1 | -0.0151306 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0151003 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0150646 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0149973 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0149567 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.014704 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0147013 |
| CDCA2 | cell division cycle associated 2 | -0.0146922 |
| HMGB1 | high mobility group box 1 | -0.014598 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0145781 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0145173 |
| CDH13 | cadherin 13 | -0.0144528 |
| H1-0 | H1.0 linker histone | -0.014355 |
