| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.1383 |
| PKM | pyruvate kinase, muscle | 0.107264 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0870972 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0815418 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0738861 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0732786 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0643949 |
| EGFR | epidermal growth factor receptor | 0.0631645 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0605623 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0521457 |
| ENO1 | enolase 1, (alpha) | 0.0489243 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0486373 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0475048 |
| PCBP2 | poly(rC) binding protein 2 | 0.0394824 |
| POTEF | POTE ankyrin domain family, member F | 0.0392175 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0378588 |
| RPL3 | ribosomal protein L3 | 0.0378299 |
| TJP1 | tight junction protein 1 | 0.0374362 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0372638 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.037094 |
| PRELID2 | PRELI domain containing 2 | 0.0356347 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0348962 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0340651 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0331422 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0330673 |
| VCL | vinculin | 0.0329445 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0320061 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0316682 |
| DUSP4 | dual specificity phosphatase 4 | 0.0308665 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0295643 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0291381 |
| GLI3 | GLI family zinc finger 3 | 0.0287775 |
| MYO5C | myosin VC | 0.0287559 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0286065 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0278 |
| PTMS | parathymosin | 0.0266876 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0265147 |
| JMJD1C | jumonji domain containing 1C | 0.026074 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0258845 |
| USP47 | ubiquitin specific peptidase 47 | 0.0255604 |
| HDAC9 | histone deacetylase 9 | 0.0255054 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0254518 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.025399 |
| PDGFC | platelet derived growth factor C | 0.0253107 |
| PARD3 | par-3 family cell polarity regulator | 0.0250605 |
| LDHA | lactate dehydrogenase A | 0.024799 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0242443 |
| B2M | beta-2-microglobulin | 0.023963 |
| ANXA3 | annexin A3 | 0.0239229 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0238415 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0235902 |
| ZNF438 | zinc finger protein 438 | 0.0233851 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0233755 |
| SMYD3 | SET and MYND domain containing 3 | 0.0232568 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0229158 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0223968 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0221679 |
| PNN | pinin, desmosome associated protein | 0.0221071 |
| EFNA5 | ephrin-A5 | 0.0218646 |
| MLEC | malectin | 0.0217515 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0217015 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0216599 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.02161 |
| MYO9A | myosin IXA | 0.0214708 |
| CCNL1 | cyclin L1 | 0.0210913 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0210319 |
| BRD2 | bromodomain containing 2 | 0.0209659 |
| LOXL3 | lysyl oxidase-like 3 | 0.0208513 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0208019 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0206599 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0206349 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0204087 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0202362 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0195333 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0194683 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0194325 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0194269 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0193977 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0192906 |
| PLK2 | polo-like kinase 2 | 0.0192805 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0192435 |
| GSE1 | Gse1 coiled-coil protein | 0.0192219 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0191626 |
| OLA1 | Obg-like ATPase 1 | 0.018891 |
| RAD51B | RAD51 paralog B | 0.0188111 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0185707 |
| NBEA | neurobeachin | 0.0184974 |
| TPM3 | tropomyosin 3 | 0.018485 |
| VMP1 | vacuole membrane protein 1 | 0.0183364 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0182776 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0182531 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0182517 |
| ANXA1 | annexin A1 | 0.0182012 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.018157 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0180862 |
| PHF14 | PHD finger protein 14 | 0.0180625 |
| ITSN2 | intersectin 2 | 0.0176413 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0176266 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0175543 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0173817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.245549 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218085 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.15467 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.110046 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0878789 |
| RPL35A | ribosomal protein L35a | -0.0697104 |
| S100A6 | S100 calcium binding protein A6 | -0.0601907 |
| ACTG1 | actin gamma 1 | -0.057372 |
| RPS6 | ribosomal protein S6 | -0.0549051 |
| RPLP2 | ribosomal protein, large, P2 | -0.0524069 |
| RPL34 | ribosomal protein L34 | -0.0504528 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0482925 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0446383 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0430987 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0383005 |
| EVI5 | ecotropic viral integration site 5 | -0.0372635 |
| RBM39 | RNA binding motif protein 39 | -0.0350541 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0344504 |
| OGA | O-GlcNAcase | -0.0338414 |
| RRBP1 | ribosome binding protein 1 | -0.0332436 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0326382 |
| FAM162A | family with sequence similarity 162, member A | -0.0318855 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0316978 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0314609 |
| RPS27A | ribosomal protein S27a | -0.0306874 |
| H3-3B | H3.3 histone B | -0.0305038 |
| GOLGA4 | golgin A4 | -0.030067 |
| RPS29 | ribosomal protein S29 | -0.030001 |
| MT2A | metallothionein 2A | -0.0291401 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0285793 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0277203 |
| USP3 | ubiquitin specific peptidase 3 | -0.0273665 |
| RPS19 | ribosomal protein S19 | -0.0271174 |
| KPNB1 | karyopherin (importin) beta 1 | -0.026975 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0268053 |
| RPL37 | ribosomal protein L37 | -0.0261866 |
| GNAS | GNAS complex locus | -0.0253173 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0252943 |
| RPS3 | ribosomal protein S3 | -0.0250909 |
| RPL37A | ribosomal protein L37a | -0.0250359 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0250183 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0242686 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239058 |
| RPL36A | ribosomal protein L36a | -0.0237419 |
| RPL32 | ribosomal protein L32 | -0.0232774 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0232526 |
| RPL13A | ribosomal protein L13a | -0.02285 |
| AHNAK | AHNAK nucleoprotein | -0.0227684 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0227174 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.022505 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0221997 |
| RPL7A | ribosomal protein L7a | -0.0216892 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0215266 |
| RPL26 | ribosomal protein L26 | -0.0215008 |
| RPS16 | ribosomal protein S16 | -0.0209591 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0208274 |
| RPS21 | ribosomal protein S21 | -0.0207085 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.020322 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.020279 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0202735 |
| RPS28 | ribosomal protein S28 | -0.0201855 |
| RPS24 | ribosomal protein S24 | -0.0200818 |
| RPS11 | ribosomal protein S11 | -0.0200623 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0198931 |
| RPS23 | ribosomal protein S23 | -0.0198823 |
| TMEM41B | transmembrane protein 41B | -0.0197865 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0195357 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0195104 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0194019 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0194001 |
| TXNL1 | thioredoxin-like 1 | -0.0193964 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0193199 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.019303 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0192764 |
| TMEM263 | transmembrane protein 263 | -0.0191995 |
| IRX2 | iroquois homeobox 2 | -0.0191214 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0189463 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0187326 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0186039 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0184663 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0183462 |
| DENND5B | DENN/MADD domain containing 5B | -0.0180807 |
| NEK7 | NIMA-related kinase 7 | -0.0180544 |
| ATXN2 | ataxin 2 | -0.017978 |
| RLF | rearranged L-myc fusion | -0.017842 |
| RPS10 | ribosomal protein S10 | -0.0176882 |
| CCDC47 | coiled-coil domain containing 47 | -0.0176848 |
| CEP95 | centrosomal protein 95kDa | -0.0175119 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0174608 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0174272 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0172899 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0171598 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0171258 |
| RPL14 | ribosomal protein L14 | -0.0170829 |
| SEC24D | SEC24 family member D | -0.0168371 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0168217 |
| RPL9 | ribosomal protein L9 | -0.0166756 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0166415 |
| TUBB | tubulin, beta class I | -0.0163808 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0163634 |
