| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.149186 |
| COL6A3 | collagen, type VI, alpha 3 | 0.121835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104873 |
| LDHA | lactate dehydrogenase A | 0.100698 |
| SFTPA2 | surfactant protein A2 | 0.0976537 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0822114 |
| ENO1 | enolase 1, (alpha) | 0.0802016 |
| CD44 | CD44 molecule (Indian blood group) | 0.078681 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0760036 |
| CDH13 | cadherin 13 | 0.0747615 |
| NDRG1 | N-myc downstream regulated 1 | 0.0742915 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0739189 |
| HDAC9 | histone deacetylase 9 | 0.0733607 |
| VCAN | versican | 0.0720085 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0657217 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0651128 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0640455 |
| CALR | calreticulin | 0.0619947 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0597833 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0593729 |
| PGK1 | phosphoglycerate kinase 1 | 0.0576692 |
| RND3 | Rho family GTPase 3 | 0.0551901 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0544751 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0524308 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0509297 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0486441 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0477251 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0460195 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0455694 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0445078 |
| SQSTM1 | sequestosome 1 | 0.0417468 |
| GOLGB1 | golgin B1 | 0.0414583 |
| PDE10A | phosphodiesterase 10A | 0.0401095 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0380327 |
| ZC3H11D | zinc finger CCCH-type containing 11D | 0.0368821 |
| RPS12 | ribosomal protein S12 | 0.0358351 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0355935 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.035321 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0348672 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0347987 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0344673 |
| DST | dystonin | 0.0343475 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0341153 |
| SMAD3 | SMAD family member 3 | 0.033755 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0330613 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0328482 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0327001 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326249 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.032044 |
| MORF4L2 | mortality factor 4 like 2 | 0.031986 |
| DTNA | dystrobrevin, alpha | 0.0317058 |
| VIM | vimentin | 0.0314995 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0312111 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0310986 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0310547 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0305971 |
| SYNJ2 | synaptojanin 2 | 0.0304787 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.029944 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0298695 |
| KIAA1217 | KIAA1217 | 0.0297722 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.029462 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0291901 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.029057 |
| FNIP1 | folliculin interacting protein 1 | 0.0284797 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0283717 |
| RUNX1 | runt-related transcription factor 1 | 0.02809 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0280408 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0277578 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0276263 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.027599 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0274618 |
| MCL1 | myeloid cell leukemia 1 | 0.0268538 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0267852 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0267228 |
| ASPH | aspartate beta-hydroxylase | 0.0263511 |
| HMGA2 | high mobility group AT-hook 2 | 0.0255041 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.025338 |
| NRXN3 | neurexin 3 | 0.0251092 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0251079 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0248894 |
| BPTF | bromodomain PHD finger transcription factor | 0.0244406 |
| TMEM132D | transmembrane protein 132D | 0.0243952 |
| UST | uronyl-2-sulfotransferase | 0.0241027 |
| B2M | beta-2-microglobulin | 0.0240625 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.024042 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0239915 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0237673 |
| KYNU | kynureninase | 0.0234766 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0234523 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0233463 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.023273 |
| NONO | non-POU domain containing, octamer-binding | 0.0232255 |
| NAV1 | neuron navigator 1 | 0.023167 |
| ATXN1 | ataxin 1 | 0.0231565 |
| GPC6 | glypican 6 | 0.0230797 |
| EXOC4 | exocyst complex component 4 | 0.0230476 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0229839 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0229618 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0228614 |
| ANXA1 | annexin A1 | 0.0228504 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0871916 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0848698 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0774883 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0672227 |
| RTN4 | reticulon 4 | -0.0491899 |
| FN1 | fibronectin 1 | -0.0429367 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0415921 |
| CADM1 | cell adhesion molecule 1 | -0.0382946 |
| PTMA | prothymosin, alpha | -0.0382853 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0371419 |
| WDR45B | WD repeat domain 45B | -0.0343956 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0337656 |
| RPS6 | ribosomal protein S6 | -0.0327506 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.028243 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0268259 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0259568 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0252531 |
| TAPBP | TAP binding protein (tapasin) | -0.0251917 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0250944 |
| CCNL1 | cyclin L1 | -0.0250932 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0249488 |
| COL1A1 | collagen, type I, alpha 1 | -0.024227 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0240463 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0235996 |
| ATP13A3 | ATPase type 13A3 | -0.0232623 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0232042 |
| RPS24 | ribosomal protein S24 | -0.0231821 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0231625 |
| CTSD | cathepsin D | -0.0226257 |
| SBF2 | SET binding factor 2 | -0.0221739 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.022108 |
| FTL | ferritin, light polypeptide | -0.0217427 |
| HLA-B | major histocompatibility complex, class I, B | -0.0217307 |
| ZNF292 | zinc finger protein 292 | -0.0214596 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0213995 |
| QKI | QKI, KH domain containing, RNA binding | -0.0212048 |
| TMEM41B | transmembrane protein 41B | -0.0208552 |
| SETD5 | SET domain containing 5 | -0.020755 |
| ARF4 | ADP-ribosylation factor 4 | -0.0203094 |
| HELZ | helicase with zinc finger | -0.02002 |
| FRMD4A | FERM domain containing 4A | -0.0199796 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0198538 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0195662 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.01939 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0192227 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0189921 |
| TUBB | tubulin, beta class I | -0.018842 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0187427 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0187346 |
| NABP1 | nucleic acid binding protein 1 | -0.018611 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0185936 |
| DSTN | destrin (actin depolymerizing factor) | -0.0185783 |
| TMEM123 | transmembrane protein 123 | -0.0179781 |
| DIAPH3 | diaphanous-related formin 3 | -0.0176872 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0176578 |
| PHF21A | PHD finger protein 21A | -0.017366 |
| BICC1 | BicC family RNA binding protein 1 | -0.0173442 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0169407 |
| TXNIP | thioredoxin interacting protein | -0.016859 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0167673 |
| RNF149 | ring finger protein 149 | -0.016726 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0165673 |
| ACTG1 | actin gamma 1 | -0.0163815 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0163247 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0162779 |
| TBC1D12 | TBC1 domain family, member 12 | -0.016199 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0159967 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0159759 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0159561 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0158561 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0158298 |
| MED14 | mediator complex subunit 14 | -0.0157461 |
| FAM162A | family with sequence similarity 162, member A | -0.0156388 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0155886 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0154819 |
| TPX2 | TPX2, microtubule-associated | -0.0154214 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0152688 |
| NKTR | natural killer cell triggering receptor | -0.0151279 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0149052 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.014881 |
| ZFR | zinc finger RNA binding protein | -0.0145432 |
| NEK7 | NIMA-related kinase 7 | -0.0143369 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0140726 |
| RBM6 | RNA binding motif protein 6 | -0.0140632 |
| VCL | vinculin | -0.0139751 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0139219 |
| CDCP1 | CUB domain containing protein 1 | -0.0138936 |
| WASF2 | WAS protein family, member 2 | -0.0137811 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0136319 |
| SPAG9 | sperm associated antigen 9 | -0.0136042 |
| SEPTIN7 | septin 7 | -0.0133768 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0133091 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0132812 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0132717 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0131079 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.013073 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0130258 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0130107 |
| DEK | DEK proto-oncogene | -0.0130003 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.012986 |
