| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.448965 |
| ENO1 | enolase 1, (alpha) | 0.127815 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.124972 |
| LDHA | lactate dehydrogenase A | 0.110117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.101209 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.100814 |
| NDRG1 | N-myc downstream regulated 1 | 0.0996705 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0978352 |
| CDH13 | cadherin 13 | 0.0854665 |
| STC1 | stanniocalcin 1 | 0.0802232 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0776023 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0741053 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.071607 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0701684 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0690146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0688581 |
| PRSS23 | protease, serine, 23 | 0.0684579 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0662714 |
| HMGA2 | high mobility group AT-hook 2 | 0.0655334 |
| MT2A | metallothionein 2A | 0.0651635 |
| VIM | vimentin | 0.0634538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0586877 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0581343 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0579151 |
| PGK1 | phosphoglycerate kinase 1 | 0.0578913 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0577478 |
| CALR | calreticulin | 0.0570676 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0567398 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0536623 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0532668 |
| CD44 | CD44 molecule (Indian blood group) | 0.0525011 |
| KYNU | kynureninase | 0.0522067 |
| NRXN3 | neurexin 3 | 0.0489298 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.047437 |
| RPS12 | ribosomal protein S12 | 0.0470282 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0469448 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0461218 |
| RPL37A | ribosomal protein L37a | 0.0443806 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0421584 |
| ECE1 | endothelin converting enzyme 1 | 0.0417531 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0416773 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0410957 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0409978 |
| ATXN1 | ataxin 1 | 0.0398922 |
| RND3 | Rho family GTPase 3 | 0.0398781 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0398493 |
| ASPH | aspartate beta-hydroxylase | 0.0392797 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.039226 |
| ANO6 | anoctamin 6 | 0.0389708 |
| FTL | ferritin, light polypeptide | 0.0389448 |
| MCL1 | myeloid cell leukemia 1 | 0.0374053 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0368412 |
| INTS6 | integrator complex subunit 6 | 0.0368038 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0364388 |
| SETBP1 | SET binding protein 1 | 0.0362335 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0362208 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.035722 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0355635 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0354604 |
| DST | dystonin | 0.0344551 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0344056 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0343794 |
| EGFR | epidermal growth factor receptor | 0.0342966 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0342533 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0341575 |
| GOLGB1 | golgin B1 | 0.0338575 |
| PRELID2 | PRELI domain containing 2 | 0.0324336 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0320633 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0318806 |
| GLUL | glutamate-ammonia ligase | 0.0313762 |
| EFNA5 | ephrin-A5 | 0.0313222 |
| FNIP1 | folliculin interacting protein 1 | 0.031056 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0308537 |
| LOXL2 | lysyl oxidase-like 2 | 0.0308405 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0307546 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0304432 |
| HLA-A | major histocompatibility complex, class I, A | 0.0303671 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0296206 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0294014 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0293013 |
| MLEC | malectin | 0.0291118 |
| MYLK | myosin light chain kinase | 0.0290098 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0287582 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.028612 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0283922 |
| RPS27A | ribosomal protein S27a | 0.0278437 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.027591 |
| CANX | calnexin | 0.027423 |
| MORF4L2 | mortality factor 4 like 2 | 0.0271489 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.027118 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0270419 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0270233 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0269991 |
| MAP1B | microtubule-associated protein 1B | 0.026689 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0265575 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0263485 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0262688 |
| TLN1 | talin 1 | 0.0261743 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0260333 |
| FAM13A | family with sequence similarity 13, member A | 0.0257461 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GARS1 | glycyl-tRNA synthetase 1 | -0.0579789 |
| HLA-B | major histocompatibility complex, class I, B | -0.0546054 |
| H3-3B | H3.3 histone B | -0.0476455 |
| SETD5 | SET domain containing 5 | -0.0472821 |
| COL1A1 | collagen, type I, alpha 1 | -0.0451422 |
| SEC24D | SEC24 family member D | -0.044671 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0412837 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0379308 |
| RTN4 | reticulon 4 | -0.0360235 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0344704 |
| RNF24 | ring finger protein 24 | -0.0342413 |
| MT1X | metallothionein 1X | -0.0327502 |
| POTEF | POTE ankyrin domain family, member F | -0.0314531 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0302606 |
| SRPK2 | SRSF protein kinase 2 | -0.0300971 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0295426 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0288769 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0288714 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0275298 |
| SDC4 | syndecan 4 | -0.0267843 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0267464 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0263681 |
| TMEM263 | transmembrane protein 263 | -0.0258989 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.025776 |
| COL1A2 | collagen, type I, alpha 2 | -0.0254956 |
| MATR3 | matrin 3 | -0.0254489 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0253904 |
| CFDP1 | craniofacial development protein 1 | -0.0253579 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0252983 |
| WDR45B | WD repeat domain 45B | -0.0252153 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0250254 |
| TXNIP | thioredoxin interacting protein | -0.0249162 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0247828 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0247367 |
| VEGFA | vascular endothelial growth factor A | -0.0245638 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0240071 |
| GLG1 | golgi glycoprotein 1 | -0.0235529 |
| USP33 | ubiquitin specific peptidase 33 | -0.0234052 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0232058 |
| RPS6 | ribosomal protein S6 | -0.0231681 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0229889 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0227385 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0227136 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0222211 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0219828 |
| COG5 | component of oligomeric golgi complex 5 | -0.0219563 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0219221 |
| RNF145 | ring finger protein 145 | -0.0214874 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0211397 |
| XPO1 | exportin 1 | -0.0210795 |
| ANKRD12 | ankyrin repeat domain 12 | -0.020968 |
| FOXJ3 | forkhead box J3 | -0.0209411 |
| ZNF292 | zinc finger protein 292 | -0.0207276 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0207106 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0206776 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0205175 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0201847 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0201678 |
| RHEB | Ras homolog enriched in brain | -0.0201266 |
| CADM1 | cell adhesion molecule 1 | -0.0200445 |
| RBM39 | RNA binding motif protein 39 | -0.0200423 |
| ACTG1 | actin gamma 1 | -0.019825 |
| CRLS1 | cardiolipin synthase 1 | -0.019604 |
| ANLN | anillin, actin binding protein | -0.0195793 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0195453 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0195116 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0194098 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0192902 |
| TMEM131 | transmembrane protein 131 | -0.0188939 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0186084 |
| TNPO3 | transportin 3 | -0.0185822 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0185807 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0185522 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0184618 |
| ZNF736 | zinc finger protein 736 | -0.0184448 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0184394 |
| CDC27 | cell division cycle 27 | -0.018381 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0182715 |
| RBM25 | RNA binding motif protein 25 | -0.0182169 |
| RNF216 | ring finger protein 216 | -0.0180638 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0180591 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0180278 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0179483 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.017925 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0178479 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0177955 |
| NOP58 | NOP58 ribonucleoprotein | -0.0177804 |
| AXL | AXL receptor tyrosine kinase | -0.0177747 |
| TNPO1 | transportin 1 | -0.0177725 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0175269 |
| SNU13 | small nuclear ribonucleoprotein 13 | -0.0174617 |
| PTN | pleiotrophin | -0.0174495 |
| MOB4 | MOB family member 4, phocein | -0.0174084 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0173616 |
| NKTR | natural killer cell triggering receptor | -0.0172949 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0172422 |
| RBM6 | RNA binding motif protein 6 | -0.0172351 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0172077 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0171026 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0169766 |
