| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.156441 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.113635 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.11299 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.108447 |
| SFTPA2 | surfactant protein A2 | 0.105351 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0955295 |
| HMGA2 | high mobility group AT-hook 2 | 0.0939784 |
| ASPH | aspartate beta-hydroxylase | 0.0929628 |
| STC2 | stanniocalcin 2 | 0.0809389 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0769122 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0734834 |
| ENO1 | enolase 1, (alpha) | 0.0731464 |
| B2M | beta-2-microglobulin | 0.0714844 |
| NRG1 | neuregulin 1 | 0.0694342 |
| PLIN2 | perilipin 2 | 0.0653486 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0625395 |
| MYOF | myoferlin | 0.0622527 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0600122 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0595531 |
| EFNA5 | ephrin-A5 | 0.0569575 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0555994 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0550318 |
| FTL | ferritin, light polypeptide | 0.0545707 |
| MCL1 | myeloid cell leukemia 1 | 0.0537413 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0531168 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0494194 |
| MT2A | metallothionein 2A | 0.0458078 |
| FAM13A | family with sequence similarity 13, member A | 0.0454989 |
| RPS12 | ribosomal protein S12 | 0.0451944 |
| FLNB | filamin B, beta | 0.0440293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0438584 |
| VIM | vimentin | 0.0419406 |
| CALR | calreticulin | 0.0411485 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0410987 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.040424 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0403462 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0390866 |
| RAI14 | retinoic acid induced 14 | 0.0384819 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.038263 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0380775 |
| CTBP2 | C-terminal binding protein 2 | 0.0380693 |
| TMSB10 | thymosin beta 10 | 0.0379693 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0379426 |
| INTS6 | integrator complex subunit 6 | 0.0376045 |
| RPL37A | ribosomal protein L37a | 0.0375418 |
| FAT1 | FAT atypical cadherin 1 | 0.0366685 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0350909 |
| S100A10 | S100 calcium binding protein A10 | 0.0340793 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0339407 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.033803 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0330745 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0329594 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.03273 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0324349 |
| AEBP2 | AE binding protein 2 | 0.0319626 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0315775 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.03155 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.031035 |
| DST | dystonin | 0.0308563 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0306986 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0306919 |
| RACK1 | receptor for activated C kinase 1 | 0.0303749 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0300941 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.029961 |
| RND3 | Rho family GTPase 3 | 0.0287862 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0287777 |
| LYST | lysosomal trafficking regulator | 0.0280835 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0279587 |
| DUSP6 | dual specificity phosphatase 6 | 0.0279394 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0277241 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0277182 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0273967 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0273748 |
| RPS27 | ribosomal protein S27 | 0.027263 |
| LMNA | lamin A/C | 0.0272426 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0272215 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0271145 |
| OXR1 | oxidation resistance 1 | 0.0270239 |
| TPM3 | tropomyosin 3 | 0.0269508 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0268889 |
| EZR | ezrin | 0.0265226 |
| RPL35A | ribosomal protein L35a | 0.026104 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0260366 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.026017 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0259454 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0258065 |
| RPS8 | ribosomal protein S8 | 0.0257523 |
| LOXL2 | lysyl oxidase-like 2 | 0.0253209 |
| PKM | pyruvate kinase, muscle | 0.0253015 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.025162 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0251232 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0249135 |
| DSTN | destrin (actin depolymerizing factor) | 0.0249036 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0248747 |
| CADM1 | cell adhesion molecule 1 | 0.0248457 |
| RPL31 | ribosomal protein L31 | 0.0247972 |
| RPL26 | ribosomal protein L26 | 0.0247017 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0244502 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0243687 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0243032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128601 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.121462 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0782175 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0697235 |
| OSMR | oncostatin M receptor | -0.0484268 |
| TMEM156 | transmembrane protein 156 | -0.0438712 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.041218 |
| FN1 | fibronectin 1 | -0.041089 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0394436 |
| ETNK1 | ethanolamine kinase 1 | -0.0356632 |
| NRP1 | neuropilin 1 | -0.0330468 |
| PELO | pelota homolog (Drosophila) | -0.0306408 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0305314 |
| SMOX | spermine oxidase | -0.0302812 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0302617 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0298545 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0295118 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0294585 |
| GLIS3 | GLIS family zinc finger 3 | -0.0289361 |
| CENPF | centromere protein F, 350/400kDa | -0.0272004 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0266175 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0263938 |
| RBM39 | RNA binding motif protein 39 | -0.0260433 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0259199 |
| FOXP1 | forkhead box P1 | -0.0254796 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0251474 |
| ETV1 | ets variant 1 | -0.0250968 |
| ETV6 | ets variant 6 | -0.025063 |
| CAB39 | calcium binding protein 39 | -0.0249852 |
| FNBP1 | formin binding protein 1 | -0.0247457 |
| COPA | coatomer protein complex, subunit alpha | -0.024263 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0242041 |
| KLHL5 | kelch-like family member 5 | -0.023388 |
| SYT1 | synaptotagmin I | -0.0233866 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.022188 |
| VCL | vinculin | -0.0220316 |
| ADD3 | adducin 3 (gamma) | -0.0213347 |
| NTN4 | netrin 4 | -0.0205247 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.020399 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0201054 |
| FAM20C | family with sequence similarity 20, member C | -0.0199713 |
| NEK7 | NIMA-related kinase 7 | -0.0199185 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0197443 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0194534 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0193892 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0193413 |
| SQSTM1 | sequestosome 1 | -0.0187882 |
| ITGA1 | integrin, alpha 1 | -0.0187339 |
| KSR1 | kinase suppressor of ras 1 | -0.018713 |
| FAF2 | Fas associated factor family member 2 | -0.0185606 |
| OGA | O-GlcNAcase | -0.0185168 |
| FMN1 | formin 1 | -0.0183347 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0181988 |
| WDR45B | WD repeat domain 45B | -0.0177922 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0175384 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0172313 |
| RBM25 | RNA binding motif protein 25 | -0.0171662 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0171588 |
| RAB31 | RAB31, member RAS oncogene family | -0.0169498 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.016936 |
| MIS18BP1 | MIS18 binding protein 1 | -0.016708 |
| RUNX2 | runt-related transcription factor 2 | -0.0166961 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0164494 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0164418 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0161493 |
| RRBP1 | ribosome binding protein 1 | -0.0161105 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0157584 |
| POU2F1 | POU class 2 homeobox 1 | -0.0157342 |
| PHF12 | PHD finger protein 12 | -0.0156982 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0156626 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0155734 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0155285 |
| PCNX1 | pecanex 1 | -0.0152295 |
| USP3 | ubiquitin specific peptidase 3 | -0.0152158 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0152083 |
| DUSP5 | dual specificity phosphatase 5 | -0.0150883 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.014914 |
| CCNJL | cyclin J-like | -0.0148442 |
| SSH1 | slingshot protein phosphatase 1 | -0.0146925 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0146728 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0146262 |
| RNF145 | ring finger protein 145 | -0.0145699 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0144412 |
| CENPE | centromere protein E, 312kDa | -0.0143817 |
| RHEB | Ras homolog enriched in brain | -0.0143607 |
| THBS1 | thrombospondin 1 | -0.0143207 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0143111 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0142557 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0142472 |
| RNF24 | ring finger protein 24 | -0.0140444 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0140089 |
| ITGB5 | integrin, beta 5 | -0.0137638 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0136753 |
| RTN4 | reticulon 4 | -0.0135682 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0134937 |
| HOMER2 | homer scaffolding protein 2 | -0.0134672 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0133844 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0133686 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0132087 |
| GOLGA3 | golgin A3 | -0.0131965 |
