| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erdafitinib _SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103941 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0867346 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0795098 |
| RPS12 | ribosomal protein S12 | 0.0751655 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0641748 |
| PCBP2 | poly(rC) binding protein 2 | 0.0590129 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0514668 |
| SET | SET nuclear proto-oncogene | 0.0488642 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0475641 |
| ENO1 | enolase 1, (alpha) | 0.0460104 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0457933 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0455876 |
| RPS19 | ribosomal protein S19 | 0.0454919 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0444372 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0442618 |
| ZNF292 | zinc finger protein 292 | 0.0437746 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0421378 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0401645 |
| RPS6 | ribosomal protein S6 | 0.0398399 |
| RPS17 | ribosomal protein S17 | 0.0394252 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0392473 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.039165 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0388179 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0381705 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0379958 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0370406 |
| NDRG1 | N-myc downstream regulated 1 | 0.0370247 |
| GOLGA4 | golgin A4 | 0.0368085 |
| DSPP | dentin sialophosphoprotein | 0.0357747 |
| RPS2 | ribosomal protein S2 | 0.0355518 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0353099 |
| LDHA | lactate dehydrogenase A | 0.0346322 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0344784 |
| PCM1 | pericentriolar material 1 | 0.0342826 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.034253 |
| RPS27 | ribosomal protein S27 | 0.0341835 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0331522 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0328684 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0325862 |
| MT2A | metallothionein 2A | 0.0321482 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0320518 |
| YBX1 | Y box binding protein 1 | 0.0320341 |
| RPL3 | ribosomal protein L3 | 0.0319405 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0317487 |
| SRPK2 | SRSF protein kinase 2 | 0.0309394 |
| RPL7 | ribosomal protein L7 | 0.0305071 |
| RPL23 | ribosomal protein L23 | 0.030161 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0295708 |
| RPL37A | ribosomal protein L37a | 0.0294587 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0290646 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0280084 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0279986 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0277598 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0276947 |
| ZNF638 | zinc finger protein 638 | 0.0275965 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0275792 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0268118 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0267639 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0267174 |
| RPS8 | ribosomal protein S8 | 0.0267026 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0263508 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0260453 |
| YAP1 | Yes-associated protein 1 | 0.025948 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0257571 |
| PNN | pinin, desmosome associated protein | 0.025222 |
| TPM3 | tropomyosin 3 | 0.0251295 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0251201 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0249596 |
| SBF2 | SET binding factor 2 | 0.0249012 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0248722 |
| PKM | pyruvate kinase, muscle | 0.0246953 |
| IRS2 | insulin receptor substrate 2 | 0.0246767 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0245622 |
| MSN | moesin | 0.0243522 |
| PRPF8 | pre-mRNA processing factor 8 | 0.02435 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0239615 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0238485 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0237987 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0236841 |
| KIZ | kizuna centrosomal protein | 0.0236631 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0234266 |
| IPO7 | importin 7 | 0.0232993 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.023283 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0228114 |
| RPS3 | ribosomal protein S3 | 0.0227462 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0226497 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0221437 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0220065 |
| COG5 | component of oligomeric golgi complex 5 | 0.0219114 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0218436 |
| PTEN | phosphatase and tensin homolog | 0.0218221 |
| STK38L | serine/threonine kinase 38 like | 0.0217385 |
| CMIP | c-Maf inducing protein | 0.0216824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0216424 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0216348 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0215463 |
| DIAPH1 | diaphanous-related formin 1 | 0.0213836 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0213717 |
| RPL36 | ribosomal protein L36 | 0.0212407 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0210992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.164582 |
| CCND1 | cyclin D1 | -0.103144 |
| PTMA | prothymosin, alpha | -0.101807 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.094643 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0799639 |
| VCL | vinculin | -0.0796782 |
| ACTG1 | actin gamma 1 | -0.0783426 |
| RPS24 | ribosomal protein S24 | -0.0754003 |
| KRT8 | keratin 8, type II | -0.0648857 |
| KRT18 | keratin 18, type I | -0.0551479 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0465631 |
| AHNAK | AHNAK nucleoprotein | -0.0455453 |
| CDH13 | cadherin 13 | -0.0432267 |
| TMSB4X | thymosin beta 4, X-linked | -0.0420102 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0419281 |
| RBP1 | retinol binding protein 1, cellular | -0.0409516 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0387718 |
| NAV2 | neuron navigator 2 | -0.0380196 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.038019 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0377905 |
| TMSB10 | thymosin beta 10 | -0.0374744 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0350807 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.03092 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0304881 |
| IER3 | immediate early response 3 | -0.0301439 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.029731 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0293555 |
| H3-3B | H3.3 histone B | -0.029131 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0285622 |
| ANLN | anillin, actin binding protein | -0.0285329 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0283504 |
| TUBB | tubulin, beta class I | -0.0277913 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0277644 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0276926 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0276696 |
| INTS6 | integrator complex subunit 6 | -0.0272512 |
| CDK12 | cyclin-dependent kinase 12 | -0.0269509 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267491 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0266528 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0265439 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0262826 |
| H1-0 | H1.0 linker histone | -0.0258293 |
| TUBA1B | tubulin, alpha 1b | -0.0256773 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0248442 |
| RPL38 | ribosomal protein L38 | -0.0247145 |
| DEK | DEK proto-oncogene | -0.0244679 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0243561 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0241034 |
| KHSRP | KH-type splicing regulatory protein | -0.0239485 |
| S100A10 | S100 calcium binding protein A10 | -0.0238436 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0237583 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0233899 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0231061 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0225157 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0223711 |
| RPLP0 | ribosomal protein, large, P0 | -0.0216106 |
| TMEM123 | transmembrane protein 123 | -0.0215734 |
| HMGB1 | high mobility group box 1 | -0.0213833 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0211829 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0208941 |
| NOP56 | NOP56 ribonucleoprotein | -0.0206363 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.020631 |
| DUSP6 | dual specificity phosphatase 6 | -0.0201785 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201487 |
| TUBA1C | tubulin, alpha 1c | -0.0200303 |
| ABLIM1 | actin binding LIM protein 1 | -0.020023 |
| TFRC | transferrin receptor | -0.0199889 |
| RPL6 | ribosomal protein L6 | -0.0198963 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0197381 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0196345 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0195839 |
| LMNA | lamin A/C | -0.0192786 |
| SDC4 | syndecan 4 | -0.0190463 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0190072 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0189684 |
| RRM2 | ribonucleotide reductase M2 | -0.0185269 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0180765 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0178636 |
| UBB | ubiquitin B | -0.0177235 |
| CAVIN1 | caveolae associated protein 1 | -0.0175659 |
| S100A4 | S100 calcium binding protein A4 | -0.01741 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | -0.0173711 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0173274 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0172012 |
| NPAS2 | neuronal PAS domain protein 2 | -0.017041 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0170114 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0167754 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0166667 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.016631 |
| MKI67 | marker of proliferation Ki-67 | -0.0164048 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0163613 |
| RPS21 | ribosomal protein S21 | -0.0163046 |
| NPR2 | natriuretic peptide receptor 2 | -0.0162512 |
| APCDD1 | adenomatosis polyposis coli down-regulated 1 | -0.0161681 |
| RPL14 | ribosomal protein L14 | -0.0160167 |
| COMMD10 | COMM domain containing 10 | -0.0157955 |
| GNAS | GNAS complex locus | -0.015526 |
| MIDN | midnolin | -0.015372 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0152359 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0151678 |
