| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erdafitinib perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erdafitinib _hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.277359 |
| COL6A3 | collagen, type VI, alpha 3 | 0.265557 |
| STC1 | stanniocalcin 1 | 0.185103 |
| VIM | vimentin | 0.146718 |
| INHBA | inhibin, beta A | 0.115303 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.1059 |
| CD44 | CD44 molecule (Indian blood group) | 0.0991979 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0956201 |
| MMP1 | matrix metallopeptidase 1 | 0.0876631 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0845528 |
| ASPH | aspartate beta-hydroxylase | 0.0774204 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0654717 |
| MYO10 | myosin X | 0.0650139 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0634311 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0632151 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0628962 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0611948 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0576339 |
| ENO1 | enolase 1, (alpha) | 0.056905 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0542143 |
| CALU | calumenin | 0.054175 |
| LDHA | lactate dehydrogenase A | 0.0539656 |
| DST | dystonin | 0.0536672 |
| LOX | lysyl oxidase | 0.0521 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0508571 |
| CALR | calreticulin | 0.0480161 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0456148 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0455635 |
| HMGA2 | high mobility group AT-hook 2 | 0.0451602 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0431939 |
| COL1A2 | collagen, type I, alpha 2 | 0.0430656 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0429909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0426311 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0421659 |
| NDRG1 | N-myc downstream regulated 1 | 0.0419669 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.041652 |
| B2M | beta-2-microglobulin | 0.0416061 |
| FAM13A | family with sequence similarity 13, member A | 0.0405158 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0397901 |
| CANX | calnexin | 0.038847 |
| HLA-B | major histocompatibility complex, class I, B | 0.0380426 |
| LOXL2 | lysyl oxidase-like 2 | 0.0379416 |
| GLIS3 | GLIS family zinc finger 3 | 0.0378466 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0374012 |
| RUNX1 | runt-related transcription factor 1 | 0.0372731 |
| COL1A1 | collagen, type I, alpha 1 | 0.0370989 |
| NAV1 | neuron navigator 1 | 0.0367698 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0362055 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0343717 |
| EMP1 | epithelial membrane protein 1 | 0.0341719 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0331213 |
| COL4A2 | collagen, type IV, alpha 2 | 0.032058 |
| FBN1 | fibrillin 1 | 0.0319269 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0317713 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0317235 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0316206 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0316179 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0314066 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0309003 |
| COL3A1 | collagen, type III, alpha 1 | 0.0308869 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0308527 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0308193 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0300331 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0299289 |
| SNX9 | sorting nexin 9 | 0.0292131 |
| FOXP1 | forkhead box P1 | 0.0292109 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0291821 |
| MCL1 | myeloid cell leukemia 1 | 0.0288652 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0287458 |
| DSPP | dentin sialophosphoprotein | 0.0284817 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0284211 |
| MAP1B | microtubule-associated protein 1B | 0.0280553 |
| ANO6 | anoctamin 6 | 0.027225 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267615 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0267593 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0264303 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.026419 |
| PGK1 | phosphoglycerate kinase 1 | 0.0264089 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0261307 |
| FAT1 | FAT atypical cadherin 1 | 0.025379 |
| SFTPA2 | surfactant protein A2 | 0.0251438 |
| COL5A2 | collagen, type V, alpha 2 | 0.0250541 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0250528 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0249729 |
| TPM3 | tropomyosin 3 | 0.0249451 |
| PCBP3 | poly(rC) binding protein 3 | 0.0246106 |
| EGFR | epidermal growth factor receptor | 0.0244745 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0243841 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0242615 |
| CTSB | cathepsin B | 0.0238746 |
| TPM4 | tropomyosin 4 | 0.0236709 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0236065 |
| FMNL2 | formin-like 2 | 0.0235654 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0231798 |
| AHNAK | AHNAK nucleoprotein | 0.0229102 |
| FRMD4A | FERM domain containing 4A | 0.0228424 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0224309 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0218136 |
| FRMD6 | FERM domain containing 6 | 0.0215337 |
| SMAD3 | SMAD family member 3 | 0.0214648 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0185336 |
| FTL | ferritin, light polypeptide | -0.0183977 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0171999 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0165414 |
| ADM | adrenomedullin | -0.0163786 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0160972 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0127755 |
| RPL35A | ribosomal protein L35a | -0.0119539 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0107068 |
| NKTR | natural killer cell triggering receptor | -0.01054 |
| NPTX1 | neuronal pentraxin I | -0.00984833 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0092453 |
| GPHN | gephyrin | -0.00871896 |
| DIAPH2 | diaphanous-related formin 2 | -0.00834545 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00826733 |
| POTEF | POTE ankyrin domain family, member F | -0.00822459 |
| RPS21 | ribosomal protein S21 | -0.00816227 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00812507 |
| NCKAP5 | NCK-associated protein 5 | -0.00805438 |
| PER1 | period circadian clock 1 | -0.00801524 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00781151 |
| G0S2 | G0/G1 switch 2 | -0.00779322 |
| RPL37A | ribosomal protein L37a | -0.00753674 |
| RPS16 | ribosomal protein S16 | -0.00750142 |
| HELZ | helicase with zinc finger | -0.00742244 |
| RBM39 | RNA binding motif protein 39 | -0.00738786 |
| HMGA1 | high mobility group AT-hook 1 | -0.00736074 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.00735613 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.00728251 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.00703912 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00699997 |
| RPS6 | ribosomal protein S6 | -0.00699991 |
| RPS24 | ribosomal protein S24 | -0.00695921 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00685456 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.00685112 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00677705 |
| USP3 | ubiquitin specific peptidase 3 | -0.00674853 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.00673245 |
| GSK3B | glycogen synthase kinase 3 beta | -0.00671475 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.00670884 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00669422 |
| SERTAD2 | SERTA domain containing 2 | -0.00666343 |
| CDK13 | cyclin-dependent kinase 13 | -0.00663586 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00653212 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00645923 |
| THOC2 | THO complex 2 | -0.00643002 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00621098 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00619532 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00614236 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.00611611 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | -0.00593906 |
| NREP | neuronal regeneration related protein | -0.0058599 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00582646 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.00568587 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00568462 |
| HDAC5 | histone deacetylase 5 | -0.00567193 |
| ANK2 | ankyrin 2, neuronal | -0.00562885 |
| TPP2 | tripeptidyl peptidase II | -0.00561992 |
| MEF2A | myocyte enhancer factor 2A | -0.00556328 |
| FAM162A | family with sequence similarity 162, member A | -0.00555778 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.005509 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.00548129 |
| CHMP2B | charged multivesicular body protein 2B | -0.00547282 |
| CD109 | CD109 molecule | -0.00539559 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.00535249 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00534845 |
| IFI44 | interferon-induced protein 44 | -0.00533462 |
| STX12 | syntaxin 12 | -0.0053305 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0053188 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.00531046 |
| DCP1A | decapping mRNA 1A | -0.00528977 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.00527043 |
| CCDC18 | coiled-coil domain containing 18 | -0.00527029 |
| ZNF432 | zinc finger protein 432 | -0.0052696 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00525075 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.00523942 |
| GRAMD1B | GRAM domain containing 1B | -0.00522021 |
| RPS27A | ribosomal protein S27a | -0.00521585 |
| RCOR1 | REST corepressor 1 | -0.00520473 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00519873 |
| PSEN1 | presenilin 1 | -0.00519496 |
| MSI2 | musashi RNA-binding protein 2 | -0.00517746 |
| RBPMS | RNA binding protein with multiple splicing | -0.00517484 |
| MEMO1 | mediator of cell motility 1 | -0.00516787 |
| FNIP2 | folliculin interacting protein 2 | -0.00511974 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 | -0.00511518 |
| WTAP | Wilms tumor 1 associated protein | -0.00509252 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.00509032 |
| NUP214 | nucleoporin 214kDa | -0.00508915 |
| CCNL1 | cyclin L1 | -0.00508733 |
| RPS25 | ribosomal protein S25 | -0.00508206 |
| RPL21 | ribosomal protein L21 | -0.00507638 |
| UFM1 | ubiquitin-fold modifier 1 | -0.00507363 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | -0.00502573 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.00501949 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.00501902 |
| OTUD5 | OTU deubiquitinase 5 | -0.00501796 |
| SNX1 | sorting nexin 1 | -0.00501665 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.00500011 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00499642 |
