| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Erlotinib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.059076 |
| VIM | vimentin | 0.0502677 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0406026 |
| TMSB10 | thymosin beta 10 | 0.0363702 |
| CDH13 | cadherin 13 | 0.0348294 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0338896 |
| POTEF | POTE ankyrin domain family, member F | 0.0327012 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319406 |
| RACK1 | receptor for activated C kinase 1 | 0.0310592 |
| RPL35A | ribosomal protein L35a | 0.0309778 |
| RPL26 | ribosomal protein L26 | 0.0306124 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0297901 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0276576 |
| GOLGA4 | golgin A4 | 0.0271883 |
| CENPF | centromere protein F, 350/400kDa | 0.0270688 |
| RPLP1 | ribosomal protein, large, P1 | 0.0269668 |
| RPLP0 | ribosomal protein, large, P0 | 0.0269151 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0267524 |
| CBX3 | chromobox homolog 3 | 0.0262305 |
| CCND1 | cyclin D1 | 0.0258285 |
| S100A6 | S100 calcium binding protein A6 | 0.0243684 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0243182 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0227811 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0215832 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0206999 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0204464 |
| TMSB4X | thymosin beta 4, X-linked | 0.0201004 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.019323 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0189908 |
| RPS3 | ribosomal protein S3 | 0.0189324 |
| RPL37A | ribosomal protein L37a | 0.018114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0181014 |
| TOX | thymocyte selection-associated high mobility group box | 0.0177292 |
| RPL31 | ribosomal protein L31 | 0.0172182 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0170208 |
| RPS24 | ribosomal protein S24 | 0.0165687 |
| SOD1 | superoxide dismutase 1, soluble | 0.0164132 |
| RPS8 | ribosomal protein S8 | 0.0159951 |
| RPL30 | ribosomal protein L30 | 0.0159227 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0155852 |
| PODXL | podocalyxin-like | 0.0155608 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0154818 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0153262 |
| RPL27 | ribosomal protein L27 | 0.014941 |
| KIF5B | kinesin family member 5B | 0.0146219 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.014614 |
| RPS6 | ribosomal protein S6 | 0.0144939 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0144754 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0143741 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0143267 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0140958 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.0140643 |
| LDHB | lactate dehydrogenase B | 0.0138329 |
| RPLP2 | ribosomal protein, large, P2 | 0.0134251 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0133338 |
| RPS23 | ribosomal protein S23 | 0.0130624 |
| RPS12 | ribosomal protein S12 | 0.0127959 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0127562 |
| RPL34 | ribosomal protein L34 | 0.0125329 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0125085 |
| FADS2 | fatty acid desaturase 2 | 0.0124972 |
| KRT18 | keratin 18, type I | 0.0122841 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0120892 |
| ZFP36 | ZFP36 ring finger protein | 0.0120439 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0120203 |
| RPS25 | ribosomal protein S25 | 0.0120112 |
| SUCNR1 | succinate receptor 1 | 0.0119342 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0118622 |
| RPL23 | ribosomal protein L23 | 0.0117595 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0117156 |
| RPS21 | ribosomal protein S21 | 0.0115754 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.0114135 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0113674 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0112046 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0112002 |
| RPL27A | ribosomal protein L27a | 0.0110811 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0110782 |
| RPL35 | ribosomal protein L35 | 0.0110369 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.0110182 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0109205 |
| SGO2 | shugoshin 2 | 0.0109203 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0109202 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0108591 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.010792 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0107069 |
| SLK | STE20-like kinase | 0.0106795 |
| GLCCI1 | glucocorticoid induced 1 | 0.0106712 |
| RPS16 | ribosomal protein S16 | 0.0106514 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0106399 |
| DSTN | destrin (actin depolymerizing factor) | 0.0106239 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 0.0106059 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0105944 |
| KAZN | kazrin, periplakin interacting protein | 0.0105791 |
| RPS4X | ribosomal protein S4, X-linked | 0.0105617 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0104874 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0104501 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0104423 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0103955 |
| RPL12 | ribosomal protein L12 | 0.0103927 |
| RPS17 | ribosomal protein S17 | 0.0103828 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.259288 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.217737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174155 |
| LOX | lysyl oxidase | -0.147009 |
| NDRG1 | N-myc downstream regulated 1 | -0.13403 |
| PLAT | plasminogen activator, tissue | -0.121221 |
| CD44 | CD44 molecule (Indian blood group) | -0.109078 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.106164 |
| FBN1 | fibrillin 1 | -0.101773 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0999898 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0889645 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0811536 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0669949 |
| NAV1 | neuron navigator 1 | -0.0647707 |
| CALR | calreticulin | -0.0631509 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0630949 |
| COL5A1 | collagen, type V, alpha 1 | -0.0629869 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.062416 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0602221 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0599952 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0599946 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0599942 |
| THBS2 | thrombospondin 2 | -0.0590893 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0574481 |
| COL5A2 | collagen, type V, alpha 2 | -0.0564848 |
| AHNAK | AHNAK nucleoprotein | -0.0562889 |
| FSTL1 | follistatin-like 1 | -0.0552554 |
| COL3A1 | collagen, type III, alpha 1 | -0.0543137 |
| CTSB | cathepsin B | -0.0521748 |
| APP | amyloid beta (A4) precursor protein | -0.0521295 |
| PKM | pyruvate kinase, muscle | -0.0514819 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0500024 |
| ANXA2 | annexin A2 | -0.0472577 |
| FLNA | filamin A, alpha | -0.0465074 |
| MB21D2 | Mab-21 domain containing 2 | -0.0463109 |
| LOXL2 | lysyl oxidase-like 2 | -0.0455938 |
| PGK1 | phosphoglycerate kinase 1 | -0.0448272 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0439207 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0429368 |
| COL1A2 | collagen, type I, alpha 2 | -0.0425675 |
| SETD5 | SET domain containing 5 | -0.0422979 |
| RUNX1 | runt-related transcription factor 1 | -0.0420473 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0408702 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0401556 |
| MYO9B | myosin IXB | -0.0401285 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0396914 |
| SFTPA2 | surfactant protein A2 | -0.0396602 |
| HLA-B | major histocompatibility complex, class I, B | -0.0394614 |
| FLNB | filamin B, beta | -0.039258 |
| CLTC | clathrin, heavy chain (Hc) | -0.0378744 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0378645 |
| OGA | O-GlcNAcase | -0.0369924 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0368588 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0348085 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.034624 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0336677 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0335496 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0335326 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0333764 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0333397 |
| GLIS3 | GLIS family zinc finger 3 | -0.0333369 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0329717 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0328158 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0326319 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0325261 |
| CD99 | CD99 molecule | -0.0319231 |
| TXNIP | thioredoxin interacting protein | -0.031599 |
| PTMA | prothymosin, alpha | -0.0313329 |
| MAP4 | microtubule-associated protein 4 | -0.0311275 |
| UBC | ubiquitin C | -0.0304925 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0304481 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0303056 |
| TMOD1 | tropomodulin 1 | -0.0296217 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0295725 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0294705 |
| LAMB1 | laminin, beta 1 | -0.0293974 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0288297 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0287885 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0285198 |
| ZNF207 | zinc finger protein 207 | -0.0283799 |
| XPO1 | exportin 1 | -0.0283729 |
| RTN4 | reticulon 4 | -0.028299 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0282426 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0279415 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.027758 |
| SP3 | Sp3 transcription factor | -0.0277193 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0273624 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0272827 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0272572 |
| TENM3 | teneurin transmembrane protein 3 | -0.0269893 |
| LMNA | lamin A/C | -0.0268252 |
| SVIL | supervillin | -0.0267003 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0265689 |
| HELZ | helicase with zinc finger | -0.026404 |
| PLEC | plectin | -0.026377 |
| JMJD1C | jumonji domain containing 1C | -0.0263361 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0261577 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0261017 |
| ADAR | adenosine deaminase, RNA-specific | -0.0258786 |
| FAM13B | family with sequence similarity 13, member B | -0.0258353 |
