| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Erlotinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Erlotinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0456725 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.039314 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0376507 |
| WDR43 | WD repeat domain 43 | 0.0357741 |
| SERINC1 | serine incorporator 1 | 0.0346734 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0323761 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0319357 |
| RPL27 | ribosomal protein L27 | 0.0310789 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0308528 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0296629 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0287214 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0285081 |
| RPS2 | ribosomal protein S2 | 0.0279621 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0274071 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.026984 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0252371 |
| NCKAP1 | NCK-associated protein 1 | 0.0247982 |
| CBX3 | chromobox homolog 3 | 0.0242617 |
| DPH6 | diphthamine biosynthesis 6 | 0.0241206 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0223459 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0217652 |
| PRKD1 | protein kinase D1 | 0.0217527 |
| OLA1 | Obg-like ATPase 1 | 0.0215147 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0214548 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.021073 |
| PRDX5 | peroxiredoxin 5 | 0.0210195 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0209959 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0203351 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0201161 |
| ZFP36 | ZFP36 ring finger protein | 0.0200964 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0200897 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0199436 |
| TLE4 | transducin-like enhancer of split 4 | 0.019727 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.019695 |
| TOP1 | topoisomerase (DNA) I | 0.0196504 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0194456 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0193862 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0188861 |
| RPL37A | ribosomal protein L37a | 0.0186397 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0185533 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0183509 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0183044 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0182588 |
| CLINT1 | clathrin interactor 1 | 0.0177662 |
| ITSN2 | intersectin 2 | 0.0176859 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0176454 |
| SEPTIN9 | septin 9 | 0.0174872 |
| BBX | bobby sox homolog (Drosophila) | 0.0174795 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0174051 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0173855 |
| TLK2 | tousled-like kinase 2 | 0.0172877 |
| VMP1 | vacuole membrane protein 1 | 0.0171857 |
| CRY1 | cryptochrome circadian clock 1 | 0.0171772 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0171723 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0170804 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0168994 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.016882 |
| SCRN1 | secernin 1 | 0.0168061 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0167406 |
| VCAN | versican | 0.0167143 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0165377 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0165128 |
| PHIP | pleckstrin homology domain interacting protein | 0.0165012 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0164803 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0163501 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0162648 |
| CCDC59 | coiled-coil domain containing 59 | 0.0162611 |
| REST | RE1-silencing transcription factor | 0.0161607 |
| TXNRD1 | thioredoxin reductase 1 | 0.0161597 |
| TMSB4X | thymosin beta 4, X-linked | 0.0159846 |
| KIF5B | kinesin family member 5B | 0.0159566 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0159259 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 0.0158963 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0158774 |
| ACVR1 | activin A receptor, type I | 0.0158522 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.015852 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0158246 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0157889 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0155759 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0154662 |
| LYST | lysosomal trafficking regulator | 0.0154256 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0152361 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.015101 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0150045 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0149926 |
| RACK1 | receptor for activated C kinase 1 | 0.0148754 |
| SRPK1 | SRSF protein kinase 1 | 0.0148303 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | 0.0147356 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0147136 |
| SEPTIN11 | septin 11 | 0.0146984 |
| OPTN | optineurin | 0.014661 |
| RPL30 | ribosomal protein L30 | 0.0145631 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0145562 |
| NES | nestin | 0.0145424 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0145168 |
| WAPL | WAPL cohesin release factor | 0.0145068 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0145005 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0144489 |
| TMEM59 | transmembrane protein 59 | 0.0144262 |
| TTBK2 | tau tubulin kinase 2 | 0.0144117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.436426 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.361842 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191885 |
| MEIS2 | Meis homeobox 2 | -0.0827299 |
| WDR45B | WD repeat domain 45B | -0.0765965 |
| LSAMP | limbic system-associated membrane protein | -0.0706498 |
| NDRG1 | N-myc downstream regulated 1 | -0.0705081 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0697936 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0618554 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0614279 |
| PTMA | prothymosin, alpha | -0.0601426 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0566819 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0540807 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0528487 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0514055 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0504121 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0491398 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.046539 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.044246 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0441426 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0434308 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.04299 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0425061 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0411498 |
| RNF213 | ring finger protein 213 | -0.0409032 |
| PLPP1 | phospholipid phosphatase 1 | -0.0392745 |
| NRG1 | neuregulin 1 | -0.0388399 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0387991 |
| PRKCA | protein kinase C, alpha | -0.038747 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0385835 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0382448 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0382339 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0381111 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0380374 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0373196 |
| JMJD1C | jumonji domain containing 1C | -0.0368518 |
| H3-3B | H3.3 histone B | -0.0367631 |
| FNBP1 | formin binding protein 1 | -0.0360586 |
| FMN1 | formin 1 | -0.035664 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0353628 |
| GLG1 | golgi glycoprotein 1 | -0.0352188 |
| VIM | vimentin | -0.0343433 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0340165 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0336739 |
| DTNA | dystrobrevin, alpha | -0.0328268 |
| PGK1 | phosphoglycerate kinase 1 | -0.0321485 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.031096 |
| CANX | calnexin | -0.0307744 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.030695 |
| GNAS | GNAS complex locus | -0.0303624 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0300175 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0299789 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0297938 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0297759 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.029628 |
| RPS19 | ribosomal protein S19 | -0.0291972 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0290197 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0289151 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0287853 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0285816 |
| RPL31 | ribosomal protein L31 | -0.0285223 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0284527 |
| CRH | corticotropin releasing hormone | -0.0284367 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.028307 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0281033 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0280667 |
| SETD5 | SET domain containing 5 | -0.0275888 |
| RIGI | RNA sensor RIG-I | -0.0273056 |
| PKM | pyruvate kinase, muscle | -0.0272517 |
| ASPH | aspartate beta-hydroxylase | -0.0272306 |
| OGA | O-GlcNAcase | -0.0271593 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0271076 |
| NRP1 | neuropilin 1 | -0.0267787 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.026614 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0261596 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0259519 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0257833 |
| FNBP4 | formin binding protein 4 | -0.025453 |
| RPL23 | ribosomal protein L23 | -0.0254108 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0253692 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0251468 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.025087 |
| RCOR1 | REST corepressor 1 | -0.0250511 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0250144 |
| PCBP2 | poly(rC) binding protein 2 | -0.0249703 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0245548 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0244491 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0243597 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.024278 |
| ENO1 | enolase 1, (alpha) | -0.024268 |
| CDK19 | cyclin-dependent kinase 19 | -0.0240126 |
| MX2 | MX dynamin-like GTPase 2 | -0.023986 |
| COPA | coatomer protein complex, subunit alpha | -0.0239407 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0239227 |
| USP34 | ubiquitin specific peptidase 34 | -0.0238531 |
| SP100 | SP100 nuclear antigen | -0.0236619 |
| FHIT | fragile histidine triad | -0.023654 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0236485 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0233959 |
| CCDC47 | coiled-coil domain containing 47 | -0.0230298 |
